??????? HRPC begins in prostate.

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Todd1963
Veteran Member


Date Joined Oct 2008
Total Posts : 3196
   Posted 1/6/2009 10:45 AM (GMT -7)   
Does HRPC start in the prostate and if this is true would it be advantages for us stage 4 guys to have the dang thing cut out while the hormones have shrunk it back to normal size? Is this a viable option? Tony you got my curiosity going on that last post. Why has my uroligist not mentioned it. How acurate is the research or is it purely speculation? Give me input. I must have input.
dx:06/03/06
Age at dx: 42 age now 45
Treated for sciatic nerve pain 6 months prior to dx.
Heavy amount of blood in urine Unable to urinate 
Lung x-ray for pnumonia revealed multiple lesions in each lung
P.S.A. at time of dx. 3216.14
Began lupron and casodex
Cat scan showed large mass in the pelvic area affecting the bladder multiple nodules in both lungs and lymph node envolvement.
Bone scan revealed possible bone involvment in the pelvic area
Biopsy 12 of 12 cores positive gleason 3+4=7
P.S.A.s since lupron 2946, 1274, 532, 5.01 1.23, .09
Begining jan 08 psa .o9, .25, .44, .86, .73, 1.34, 1.49. Doubling time is a little over 3 months
Cat Scan 12/12/08 Prostate normal size and shape. No tumors detected. Left lung clear of all nodules right lung showing only benign scar tissue. Lymph nodes normal
Bone Scan 12/24/08. Clean!!!


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 1/6/2009 11:09 AM (GMT -7)   
Get DR. Strums book (A Primer on Prostate Cancer) has plenty of info regarding about everything on PCa and such things as you asked about has information within you can read.

(withdrawing other info prior-might be to controversial)

 

Bob

Post Edited (zufus) : 1/6/2009 12:13:57 PM (GMT-7)


livinadream
Veteran Member


Date Joined Apr 2008
Total Posts : 1382
   Posted 1/6/2009 4:02 PM (GMT -7)   
Todd, I will be following this post even though I do not think I can back up and have my prostate removed.

peace to all
Dale
My PSA at diagnosis was 16.3
age 46 (current)
My gleason score from prostate was 4+5=9 and from the lymph nodes was 4+4=8
I had 44 IMRT's
Casodex
Currently on Lupron
I go to The Cancer Treatment Center of America
Married with two kids
latest PSA 5-27-08 0.11
PSA July 24th, 2008 is 0.04
PSA Dec 16th, 2008 is .06
Testosterone keeps rising, the current number is 156, up from 57 in May
cancer in 4 of 6 cores
92%
80%
37%
28%
 


dkob131
Regular Member


Date Joined Apr 2008
Total Posts : 364
   Posted 1/6/2009 4:47 PM (GMT -7)   

Todd:

I have read a few articles on this topic and it does appear that it can be a very positive result to have the prostate removed, I believe they call it "salvage surgery".  I think the studies originated out of John Hopkins, I remeber the statement that "they believe over 50% of HRPC does originate in the original tumor that is in the prostate".  If you google something like "Hormone resistant prostate cancer and salvage surgery" I'm sure you'll run across the articles I am referring to.

By the way, I live right down the street from you I think.  Lacey Washington.

David

 


 54 y.o.
 Diagnosed 4/10/08
 DRE Normal
 PSA-5.5
 Biopsy- 12 cores, 4 positive highest 4+4=8
 Bone scan, CT scan and Chest X-ray clear 4/16/08
 Urologist suggested surgery 4/16/08
 MRI on 4/24/08 clear no suggestion of lymph node   involvement.
 4/24/08 -Started on Lupron and Casodex preparing for HBRT and IMRT in late July.  This treatment will not preclude me from surgery if I change my mind.
Decide to have DaVinci surgery after another consult with surgeon.
6/19/08- DaVinci surgery at University of Washington.
6/25/08- Path report, clear margins, no noted extension
9/12/08- PSA <0.02 
12/05/08-PSA <0.02 Six months after surgery 


dkob131
Regular Member


Date Joined Apr 2008
Total Posts : 364
   Posted 1/6/2009 5:27 PM (GMT -7)   
I was wrong it is not called salvage surgery, it is called "debulking the tumor".
 
David
 54 y.o.
 Diagnosed 4/10/08
 DRE Normal
 PSA-5.5
 Biopsy- 12 cores, 4 positive highest 4+4=8
 Bone scan, CT scan and Chest X-ray clear 4/16/08
 Urologist suggested surgery 4/16/08
 MRI on 4/24/08 clear no suggestion of lymph node   involvement.
 4/24/08 -Started on Lupron and Casodex preparing for HBRT and IMRT in late July.  This treatment will not preclude me from surgery if I change my mind.
Decide to have DaVinci surgery after another consult with surgeon.
6/19/08- DaVinci surgery at University of Washington.
6/25/08- Path report, clear margins, no noted extension
9/12/08- PSA <0.02 
12/05/08-PSA <0.02 Six months after surgery 


divo
Veteran Member


Date Joined Jul 2008
Total Posts : 637
   Posted 1/6/2009 5:45 PM (GMT -7)   
Todd, We did salvage surgery or debulking the tumor...but it was after radiation, and had very difficult SEs.....However, you have not had radiation. You might look into it...Di
Husband Pete
dx Jan 2001 gleason 4 + 3 PSA 16.5
Seed implant and conformal radiation and Lupron from Jan 2001 to Jan2002
2005 Dec PSA began to rise from .5 to 8 within 6 months
Salvage surgery at MSK 9/06 Dr. Eastham
Fistula operation 2/07 MSK Dr. Wong
Many cystoscopies and ER visits with strictures
Catheter for one year....Catheter taken out Sept 07..
Total Incontinence since then....
PSA .52 3/08
AUS Operation at MSK Sept 8 2008 Dr. Sandhu
Activated Oct 28th Dr. Sandhu..MSK
Some difficulty with AUS arising Nov 10 2008
Meeting with Dr. Sandhu to discuss AUS problems and new PSA test Dec 11, 2008
PSA .6 12/08
Waiting to see if AUS gets better results
Complete hip replacement surgery coming up Jan 9, 2009


Todd1963
Veteran Member


Date Joined Oct 2008
Total Posts : 3196
   Posted 1/6/2009 7:21 PM (GMT -7)   
Thanks for the post. I do believe I will talk to my Dr. about this surgery. Perhaps it will keep my lung and bone tumors from becoming H.R. I did read somewhere however that during autopsies that when cancer had spread to other organs that it actually made its own testosterone fuel to keep it growing and growing. Much like the energiser bunny I think Todd
dx:06/03/06
Age at dx: 42 age now 45
Treated for sciatic nerve pain 6 months prior to dx.
Heavy amount of blood in urine Unable to urinate 
Lung x-ray for pnumonia revealed multiple lesions in each lung
P.S.A. at time of dx. 3216.14
Began lupron and casodex
Cat scan showed large mass in the pelvic area affecting the bladder multiple nodules in both lungs and lymph node envolvement.
Bone scan revealed possible bone involvment in the pelvic area
Biopsy 12 of 12 cores positive gleason 3+4=7
P.S.A.s since lupron 2946, 1274, 532, 5.01 1.23, .09
Begining jan 08 psa .o9, .25, .44, .86, .73, 1.34, 1.49. Doubling time is a little over 3 months
Cat Scan 12/12/08 Prostate normal size and shape. No tumors detected. Left lung clear of all nodules right lung showing only benign scar tissue. Lymph nodes normal
Bone Scan 12/24/08. Clean!!!


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 1/6/2009 7:30 PM (GMT -7)   
Hi Todd,
Some experienced responders here. HRPC will likely occur where the largest tumors can be found. In men that still have the prostate, that is a likely location. Why this is I cannot say specifically, but it is why there is salvage surgery. This does not tend to be curative surgery but rather intended to delay the onset of HRPC. In patients with extended visible mets it is not effective. But our sweet Lady Di, and DK are right...look into it...Ask your oncologists if it is right for you.

Tony
Age 46 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007 @ The City of Hope
Post-Op Pathology: Gleason 4+3=7, positive margins, Extra Prostatic Extension (EPE)
Bilateral seminal vesicle invasion (SVI); Stage pT3b, N0, Mx
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (September 17 '08): <0.1 ~ Undetectable!
 
You can visit my Journey at:
 
STAY POSITIVE!
 
 

New Topic Post Reply Printable Version
Forum Information
Currently it is Thursday, February 22, 2018 2:14 AM (GMT -7)
There are a total of 2,931,890 posts in 321,686 threads.
View Active Threads


Who's Online
This forum has 160392 registered members. Please welcome our newest member, p12live.
233 Guest(s), 2 Registered Member(s) are currently online.  Details
WeightLoss, geezernow