First, I'm surprised the doctor didn't do the first injection in the office, but maybe he felt you could handle it, as you were experienced with Trimix? Caverject is the commercial name of prostaglandin/alprostadil. I have used Caverject powdered that I had to reconstitute in bacteriostatic sterile water to make the solution. The powder I had was 20mcg strength. That is the amount of drug that was in 1ml of water. So that means that you actually have 5ml's of 20mcg strength prostaglandin/alprostadil. Most of the guys injecting prostaglandin/alprostadil here do so in much smaller amounts than users of Bimix or Trimix. A little goes a long way, as it is the strongest of the 3 types. For info purposes, Trimix is next strongest, as it contains prostagandlin/alprostadil. with the Bimix drugs. Bimix is weakest, containing no prostaglandin/alprostadil.
As to pain, it's almost a general experience with guys that the prostaglandin/alprostadil causes the most trouble with pain and aching. In my case, not necessarily pain as such, but a very painful aching, if you can understand what I mean. It really aches and spreads throughout the penis, testicles and abdomen while working just great to create a usually almost rock hard erection. The aching begins shortly after injection and increases as the time goes on. This is the drug that you are most likely to have the famous over 4 hour erections with.
You say you have used Trimix before. How did you react to it, as far as results of erection and aching? This will give you an idea of what the straight stuff may do for you. I used the 20mcg strength doses by drawing around .15cc/ml (that's the 15 mark on an insulin syringe), using a .5cc or 1cc insulin syringe with a 30 ga, 5/16 inch needle. Injection technique is the same as you would use for Trimix. Since you haven't tried it before, I'd start with a low dose and work myself up. Maybe inject .05cc/ml (5 on the barrel) the first time and see what happens. Slowly move up by 5's until you find your spot. Have some real Suafed pills available- not the generic or non-epe. stuff, to help reduce the erection if it goes over the 4 hour limit.
I'm curious- if you had done Trimix before, it must have been from a different doctor? I can't see why your current one would object to Trimix. There's really no statistical way to prove his point in the literature, that I am aware of. Maybe it's something he read or heard sometime in the past.
Make sure the druggist gives you the bacteriostatic water to go with the pwoder (If you indeed do get a powder in a vial) and some info on how much to add to reconstitute the vial, if powder. If it is already liquid, keep refrirgerated, not frozen. Shelf life says 3 months, but mine went 6 months or more. As long as you practice sterile drawing technique and the liquid doesn't turn milky it should he fine.
James C. Age 61
Co-Moderator- Prostate Cancer Forum
4/07 PSA 7.6, referred to Urologist, recheck 6.7
7/07 Path report: 3 of 16 PCa, 5% involved, left lobe , GS 3/3:6.
9/07 Nerve sparing
open Retropubic Radical Prostatectomy
9/07 Post-op Path Report: GS 3+3=6 Staging pT2c, 110gms, margins clear
16 mts: ED- 50 mg Viagra 3X week, pump daily,Trimix .35ml 2X week continues
PSA's: 3 mts-.04, 6 mts.-.04, 9 mts.-.04, 12 mts.-.04, 16mts.-.04
Post Edited (James C.) : 1/23/2009 7:01:28 PM (GMT-7)