Study of 328 men post radiations~survival indication~comparative info

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zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 1/25/2009 7:58 AM (GMT -6)   
This was from the Int. Journal of Radiation Oncology and is now dated information (2002 era is when I got the data, could be older than that). Looking at my notes I transposed on this from years ago.
 
Study of 328 men in the study as to post radiations, nadir (lowest level psa achieved) showing how they fared as to survival times with certain psa levels. Nothing is in stone on PCa, we don't know all the parameters herein of those patients...thus you cannot assess exactly how you would do. It is interesting comparitive data, might give us clue if nothing else. This is the findings on survival percentages to the good side, what we want to see and hear.
 
.5 or <      at 5yrs.,  no recurrance of PCa to 10 yrs.
.5 - 1.0     87% at  8 yrs. out
1.0 - 2.0   79% at 10 yrs. out
2.0 >        67% at 13 yrs. out
 
Also  .5 or <  92% at 10 yrs.   (first .5 above was if no increase in psa found within the first 5 years and if so those patients had no recurrance within the 10 yr. period)
 
I am not endorsing one method over another, although I question any treatments as to perfection.
Just interesting comparitive data perhaps some others have not looked into abstracts on anything. They are out there on all modalities, do look at them. Some are almost unreadable by us laypersons but don't let that stop you from trying to decern them.
 
The patients that do very well post radiations..this info may boost your spirits 90-100% (maybe). This patient group was radiations only, not combined with ADT3, which could change it all and maybe either way...PCa is bizzare.
 
 
 


 


livinadream
Veteran Member


Date Joined Apr 2008
Total Posts : 1382
   Posted 1/25/2009 10:00 AM (GMT -6)   
Not sure I understand this. So how does a person like me fit into this? I like plugging my numbers in to obtain stats.

thanks for your insight.
Dale
My PSA at diagnosis was 16.3
age 46 (current)
My gleason score from prostate was 4+5=9 and from the lymph nodes was 4+4=8
I had 44 IMRT's
Casodex
Currently on Lupron
I go to The Cancer Treatment Center of America
Married with two kids
latest PSA 5-27-08 0.11
PSA July 24th, 2008 is 0.04
PSA Dec 16th, 2008 is .06
Testosterone keeps rising, the current number is 156, up from 57 in May
cancer in 4 of 6 cores
92%
80%
37%
28%
 


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 1/25/2009 2:00 PM (GMT -6)   
Dale I love you man as a brother and so sorry you have to deal with this being so much younger, I was fairly young at 51 when diagnosed via total urinary blockage (hello to me), knew -0- about PCa back then.

No you cannot just plug in your self into this because the abstract was for men whom did only radiations (external), no drug therapies envolved. It is only meant for comparision and contrast, there are other radiation abstracts to look at and with some other variables and different set of patients. You need to search and see what group is closest to what you are dealing with to maybe have alittle more data....nothing in stone on PCa, exceptions always show up, so you can not call this totally definitive, but you do not throw them out either. It may be useful to you in planning a second protocol, or various reasons.

There is a radiation study that shows longer survival time for folks whom did ADT3 combo drugs 5-6 months prior to radiations over the folks that did only radiations (via the same machines and exposure levels) I believe it was called Bolla Study (from my memory right now). At the time I was looking down the double barrels of PCa in 2002, this seemed logically the way for me to go with basically uncureable stats to begin with, I would have lost at surgery but could have tried it, radiation can do beyond the gland and was considered pretty tolerable and not to likely for complications. I did look into surgery first, got the revelation of a life time with doc-A and doc-B: curative and 1% chance of incontinence & doc-B- no way will I do surgery on you (I had great insurance)...my stats were terrible..he was totally honest, just to make sure I got 6 more opinions (4 more via correspondence)=10 and books, tapes, internet etc. Then jumped into that plan, I don't regret the protocol, I have issues with agendas and lack of honesty that I witnessed.

Dale you will have to probably see how your results go on the current protocol, if it shows continuous psa rises, then you watch it like a hawk is good advice. There are places sometimes whereby you can get a walkin psa test and have results mailed to you and your doc, one in Michigan here is at Crittenton Hospital it costs $15 and you do not have to live here or nothing. You get the results via mail within 5 days or so. I would go often especially when I am in limbo land and had a psa rise situation, of course I also compare with the tests from my docs office, mine are faster and when I want them, who cares about $15.
Hopefully a breakthrough is coming which is long overdue and whom ever comes up with it will be enriched beyond measure.
 

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