Do Biopsies leak cancer cells?

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Regular Member

Date Joined Jan 2009
Total Posts : 64
   Posted 2/2/2009 7:29 PM (GMT -6)   
Ok, I may be going nuts but why doesn't this make sense?  We get our prostates poked full of holes during biopsy and are told to wait 6-8 weeks to let the bleeding stop before treatment.  Now, if the biopsy is positive, why aren't all these little holes leaking cancer cells into our gut for those 6-8 weeks?
If this stupid disease doesn't kill me, it'll certainly drive me crazy.
Age at diagnosis 61
Resides in SW Florida
12/07 PSA 2.6  12/08 PSA 4.0
Biopsy 1/09 - 6 of 8 nodes positive 
Left - 2 of 4 positive, 15% involved, 3+4=7 Gleason
Right - 4 of 4 positive, 40% involved, 4+3=7 Gleason
DRE small nodule on right - Prostate 22.6 cc's
Planning da Vinci - searching for surgeon

Regular Member

Date Joined Apr 2008
Total Posts : 270
   Posted 2/2/2009 11:30 PM (GMT -6)   
Before I had treatment I was wondering the same thing. Everything I read indicated there is no evidence that a biopsy has ever caused cancer to spread. Regardless, being the skeptic I am I worried about this and a host of other things.

On a more practical note though, every person who has undergone treatment has had to march down the same biopsy road. That means that by far the majority who are cured or at least held in check without further spred have uncurred the same issue. In other words, the same good statistics are true and include the biopsy. Not only that why worry about it because regardless there is no alternative to the biopsy anyway. For me, I wanted to secure treatment as quick as possible so this and all other worries could be moved to the other side of treatment. Once you have the surgery the pathology report will be the best indicator of what has happened down there and what remedies need to be applied. Blessings on your doc search.

Age 61 (now 62)
Original data - pre-operation
PSA: 5.1
T1C clinical diagnosis, Needle biopsy - 10 cores, Gleason 7 = 3+4 in 1 core (40%), 7 cores Gleason 6 = 3+3 ranging from 5% to 12%
All scans negative
Lupron administered 4/9/2008 for 4 months (with idea I would undergo external beam radiation followed by seed implants - then I changed my mind).
Robotic DiVinci surgery - Dr. Fagin (Austin) May 19th
Post operative - pathology
pT2c NX MX
Gleason 3+4
Margins - negative
Extraprostatic extension - negative
seminal vesicle invasion - uninvolved
1st Post PSA <.04
2nd Post PSA <.1 10/30/2008

Tony Crispino
Veteran Member

Date Joined Dec 2006
Total Posts : 8128
   Posted 2/3/2009 12:16 AM (GMT -6)   
Tony I wouldn't sweat it...

Everyone's had one and 85% is the rate of success for containment. The fact is that no one knows. But the same question arises for all forms of treatment. Does radfiation open wholes for cancer to escape, Does surgery leak, Does Cryo Leak? No sense in worrying about that. Science has taght us that the cells need to learn how to live out of the prostate. So if they can escape, does that mean they will continue uncontrollable growth, not usually. 85% is a pretty good number.

Old Tony
Age 46 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 15, 2007
Geason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (January 13, 2009): <0.1
My Journal is at Tony's Blog  

Veteran Member

Date Joined Jul 2006
Total Posts : 681
   Posted 2/3/2009 12:45 AM (GMT -6)   
Just lask week same question / great minds
PSA up to 4.7 July 2006 , nodule noted during DRE
Biopsy 10/16/06 ,stageT2A
Aggressive Gleason 4+4=8  right side
DaVinci Surgery  January 2007
Post op confirms gleason 4+4=8
No extension or invasion identified
Few continence problems
PSA 90 day (-.01)  , (6 month -.01) , (9 month +.02) , (1 year +.02) ( 18 months +.02) (two years+.02)
One side nerve spared
success but some plaque with bimix 
born in 1941

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