Confused with the result of Biopsy

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Colin45
Regular Member


Date Joined Feb 2009
Total Posts : 216
   Posted 2/4/2009 5:05 AM (GMT -6)   
Hi new to this please help
 
 
PSA was showing 9.7
 
Had Biopsy carried out 12 core results were
 
Benign Prostatic Hyperplasia with Atrophic glands
Atypical Hyoerplasia
Prostatic Intraepithelial Neoplasia (PIN), Low-Grade
 
Both lobes show similar findings
 
Comment Both specimens show no adenocarcinoma To confirm the diagnosis by immunohistologic study is available on request
 
Microscopic Examination
Reveal diffused fibromuscular hyperplasia of the stroma. Small groups of hyperplastic glands, atrophic glands and glands with atypical hyperplasia are randomly seen in every cores.few glands with low grade Prostatic Intraepithelial Neoplasia (PIN), are also present
 
Both lobes show similar findings
 
Anybody have any idea wshat they are talking about and should I start to worry

Steve n Dallas
Veteran Member


Date Joined Mar 2008
Total Posts : 4848
   Posted 2/4/2009 6:09 AM (GMT -6)   
Welcome to the site....I'm sure others here can help...But the big question is -> what did your Doctor tell you?
 
Comment Both specimens show no adenocarcinoma said...
Adenocarcinoma is a cancer that originates in glandular tissue.
 
So seeing the phrase: "specimens show NO adenocarcinoma" sounds good.
Age 53   - 5'11"   205lbs
Overall Heath Condition - Good
PSA - July 2007 & Jan 2008 -> 1.3
Biopsy - 03/04/08 -> Gleason 6 
 
06/25/08 - Da Vinci robotic laparoscopy
Catheter in for five weeks.
Dry after 3 months.
 
10/03/08 - 1st Quarter PSA -> less then .01
01/16/09 - 2nd Quarter PSA -> less then .01
Surgeon - Keith A. Waguespack, M.D.
 


Colin45
Regular Member


Date Joined Feb 2009
Total Posts : 216
   Posted 2/4/2009 7:48 AM (GMT -6)   

Hi Steve

I am in Thailand at the moment so language causes a problem the Doctor said that there was nothing conclusive because of the Atypical Hyperplasia so I have to wait another 8 days until we get the results from further lab tests but he did not rule out cancer so I am still very worried


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 2/4/2009 11:26 AM (GMT -6)   
The good news is if this is completely accurate Low grade PIN is a non-cancerous condition (sometimes said as pre-cancerous identification of a change in cell structures-low grade is condsidered safe), it could change over time into High grade PIN or even low levels of PCa (perhaps-much later). Monitoring will be your future for being rationale on your medical issues.  Also, ask your doc whom did the pathology, if it was not done by the small handful of known experts, you might wish to pay $350-500 to have it reviewed by them (insurance should cover it too). Sometimes upon review we see different parameters from the experts. The value of second opinion on anything is not to be discarded, I seen alot over the years on PCa.
Good future for you, atleast if that is accurate you don't have to worry now.
 
The other thing that nobody wishes to hear is that biopsies can miss alot of possible target areas, so their is no warranty with biopsies, it is a best guess scenario on what was available to sample from. So, monitor your psa's and changes and watch this closely would be wise.
 
Z-Bob  Dx -2002  (bpsa 46.6  12/12 bio. 80-90% in all)


 

Post Edited (zufus) : 2/4/2009 9:33:39 AM (GMT-7)


Colin45
Regular Member


Date Joined Feb 2009
Total Posts : 216
   Posted 2/4/2009 2:37 PM (GMT -6)   
Hi Zufus
 
Thanks for you comments as I said before I am in Thailand so I do not know how trust worthy the results are at the moment I am in their hands I will have the PSA checked every 3 months and if it shows any concern I will go to Bangkok there is supposed to be a well recommended Urology section  just a few more questions could the high reading of my PSA be due to the BPH at he time of the biopsy the Doctor said the my prostate was 30% enlarged is that much

strawberry man
Regular Member


Date Joined Dec 2008
Total Posts : 23
   Posted 2/4/2009 2:41 PM (GMT -6)   
Colin 45, I am no expert, but I believe you should be very happy! I had a similar dx on skin cancer, I think it means the cells are not normal but not cancer either!

take care

Dx 4/21/08 psa 9.7  Age 58 OMG

Biopsy results  3 areas of  3+3=6 gleason

Di Vinci surgery 6/3/08

Post op 3 months and 6 months -  all clear

0 psa TYG  (thank you God)


aus
Regular Member


Date Joined Sep 2006
Total Posts : 211
   Posted 2/5/2009 7:32 AM (GMT -6)   

" just a few more questions could the high reading of my PSA be due to the BPH ?  "

Yes a high PSA reading can and often is  related to an enlarged prostate; the larger a prostate is, the more PSA is produced, so  SIZE of the gland should be factored in to the calculations  for a PSA number to have any real meaning.

" at he time of the biopsy the Doctor said the my prostate was 30% enlarged is that much ? " 

That is meaningless: 30% enlarged FROM WHAT ? You need to know what the prostate size is.


Colin45
Regular Member


Date Joined Feb 2009
Total Posts : 216
   Posted 2/5/2009 7:57 AM (GMT -6)   

Hi Aus

I just guessed that he talking about what he expected to see but as he had not seen me before a week ago I was wondering that myself

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