Severe Reaction - Lupron or Casodex???

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

mikee219
Regular Member


Date Joined Jan 2009
Total Posts : 53
   Posted 2/19/2009 1:35 PM (GMT -6)   
Hi All,

I had my Lupron shot last Tuesday, February 10. On Saturday February 14, I felt that I was developing a fever. I took aspirin on Sunday and Monday and Monday night had severe shivering and a temperature of 102ยบ, almost five degrees above normal. Nothing was found at the ER (my first ever visit) but I started seeing small blisters developing by Tuesday morning. They have continued to spread across my body since then. I've taken Alleve regularly since Monday night to control the fever until this morning when I felt, and measured, that the fever was just about gone. I saw my GP this morning and he says it's not chicken pox, thank God. He thinks it might be a reaction to the Lupron or Casodex or combination. I have an appointment this afternnon with a urologist since mine isn't in the office.

Any suggestions? Should I expect him to prescribe a steroid to get rid of this awful rash, the same as if it were poison ivy?

It looks like it's not contagious so I am back to school tomorrow so that I don't lose any more money.

Mike
Skype address: mikee219
PSA - 9, 12
Prostatic Adenocarcinoma (biopsy slides analyzed by Duke pathology)
Left base: Gleason grade 4+4=8, involving 2 of 2 cores and 22mm of 28mm core length
Left mid: Gleason grade 4+5=9, involving 2 of 2 cores and 21mm of 35mm core length
Left apex: Gleason grade 4+5=9, involving 2 of 2 cores and 13mm of 18mm core length
Right base: Gleason grade 4+5=9, involving 2 of 2 cores and 14mm of 34mm combined core length
Right mid: Gleason grade 4+5=9, involving 2 of 2 cores and 15mm of 32mm combined core length
Right apex: Gleason grade 4+5=9, involving 2 of 2 cores and 11mm of 25mm core length
Bone scan - negative
MRI (pelvic) - negative


John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4247
   Posted 2/19/2009 2:17 PM (GMT -6)   
Mikee,
Are you seeing a urologist or oncologist? I would suggest that if you are on ADT2 or 3 you should be going to a good prostate oncologist. They are more familiar with the side affects and can either perscribe other meds or change your meds. A urologist just doesn't have this kind of training.
JohnT

I had a psa of 4.4 in 1999 and steadily increasing psa every 3-6 months before reaching 40 in 5-08.Free psa ranged from 16 to 10%

I had biopsies every year, 13 total in all. I saw 5 different doctors, all urologists or urological oncologists at Long Beach, UCLA, UCSF and UCI and had an MRIS at UCSF in 2007. All tests were negative and I was told that because of all the biopsies I most likely didn't have PC, but to keep getting biopsies every year.

in Oct 08 my 13th biopsy of 25 cores indicated 2 positive cores, gleason 3+3 less that 5% in 2 cores. Doc recommended surgery.

2nd opinion from a prostate oncologist, referred by my wife's oncologists said cancer found wis indolant and statistacally insignificant, but PSA histor was a major concern and ordered a few more tests.

Color Doppler ultrasound with targeted biopsy found a transition zone tumor 18mmX16mm, gleason 3+4 and 4+3. CT and bone scans clear, but Doc thinks that there may be lymph node involvement (30% chance) because of my high PSA, and referred me for a Combidex MRI in Holland, currently scheduled for Feb 14.

Changed diet and takiing supplements while I wait. The location of the tumor plus the high psa make surgery an unlikely option. I'm still evaluatiing all treatment options and will make a decision once I get the results of the Combidex scan.

JohnT


mikee219
Regular Member


Date Joined Jan 2009
Total Posts : 53
   Posted 2/19/2009 6:09 PM (GMT -6)   
Urologist says he doesn't know. He gave me an antibiotic and something like benadryl. He said it might be the Casodex and the only way to check is to stop it. I started it at the same time as the lupron, which duke said is acceptable to control the flare. Should I stop the Casodex? I don't want the flare.
Skype address: mikee219
PSA - 9, 12
Prostatic Adenocarcinoma (biopsy slides analyzed by Duke pathology)
Left base: Gleason grade 4+4=8, involving 2 of 2 cores and 22mm of 28mm core length
Left mid: Gleason grade 4+5=9, involving 2 of 2 cores and 21mm of 35mm core length
Left apex: Gleason grade 4+5=9, involving 2 of 2 cores and 13mm of 18mm core length
Right base: Gleason grade 4+5=9, involving 2 of 2 cores and 14mm of 34mm combined core length
Right mid: Gleason grade 4+5=9, involving 2 of 2 cores and 15mm of 32mm combined core length
Right apex: Gleason grade 4+5=9, involving 2 of 2 cores and 11mm of 25mm core length
Bone scan - negative
MRI (pelvic) - negative


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 2/19/2009 7:03 PM (GMT -6)   
Mikee Duke is wrong about the 'flare thing' they may think it does not make much difference, but there is a difference, not that it would necessarily do you in or such. I mentioned Dr. Strums book which talks about this as a real event and that alot of docs miss it and I had mentioned flare issue here on the HW. Now maybe you might want to read his book, he knows tons compared to your doc and maybe you will learn more out of his book, but I am just a discount messenger who actually cares about your future.

Z-Bob
 


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 2/21/2009 10:55 AM (GMT -6)   
I spoke to Mike this morning.

His problem is not an allergy...He is in the hospital for treatment of ~ Chicken Pox. He is doing well and the fever is down. He feels good but he has to let it run it's course. He sends a thank you for all the concern, and a big "Ha Ha" about his illness.

Get well Mike! See you back soon!

Tony
Age 46 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Geason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (January 13, 2009): <0.1
 
My Journal is at Tony's Blog  
 
STAY POSITIVE!


BillyMac
Veteran Member


Date Joined Feb 2008
Total Posts : 1858
   Posted 2/22/2009 9:55 PM (GMT -6)   
A pox on them chickens mad Here's to a quick recovery from the virus Mikee and then on to battle.
Bill
1/05 PSA----2.9 3/06-----3.2 3/07-------4.1 5/07------3.9 All negative DREs
Aged 59 when diagnosed
Biopsy 6/07
4 of 10 cores positive for Adenocarcinoma-------bummer!
Core 1 <5%, core 2----50%, core 3----60%, core 4----50%
Biopsy Pathologist's comment:
Gleason 4+3=7 (80% grade 4) Stage T2c
Neither extracapsular nor perineural invasion is identified
CT scan and Bone scan show no evidence of metastases
Da Vinci RP Aug 10th 2007
Post-op pathology:
Positive for perineural invasion and 1 small focal extension
Negative at surgical margins, negative node and negative vesicle involvement
Some 4+4=8 identified ........upgraded to Gleason 8
PSA Oct 07 <0.1 undetectable
PSA Jan 08 <0.1 undetectable
PSA April 08 <0.001 undetectable (disregarded due to lab "misreporting")
PSA August 08 <0.001 undetectable (disregarded due to lab "misreporting")
Post-op pathology rechecked by new lab:
Gleason downgraded to 4+3=7
Focal extension comprised of grade 3 cells
PSA September 08 <0.01 (new lab)
PSA February 09 <0.01

New Topic Post Reply Printable Version
Forum Information
Currently it is Friday, August 17, 2018 1:59 AM (GMT -6)
There are a total of 2,993,558 posts in 328,051 threads.
View Active Threads


Who's Online
This forum has 161231 registered members. Please welcome our newest member, lxzxmhlove99801.
230 Guest(s), 7 Registered Member(s) are currently online.  Details
lxzxmhlove99801, Scaredy Cat, Patulsius, Girlie, cilly, Saipan Paradise, suchatravesty