Combidex MRI results

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John T
Veteran Member

Date Joined Nov 2008
Total Posts : 4252
   Posted 2/20/2009 1:50 PM (GMT -6)   
Just got the results from the Combidex MRI e mailed to me today. All Lymph nodes normal with one at a suspicious level 2 (5 being the highest level) This node is most likely clear.
Along with the report I got a video showing a 3D revolving picture of my lymphatic system showing all the nodes in green and one node in yellow (the suspicious node); It kind of neat to look at. I also have a disk containing 1512 pictures of my insides. The MRI also showed a 2.5cm tumor in the interior back portion of the prostate, so the MRI did see the tumor. An MRIS with endorectal coil at UCSF taken last year didn't see anything.
The trip to Holland and the $2500 cost of the MRI was well worth it. (the local hospital charged me $12,700 for a CT and bone scan). Without this information I would have had radiation to my pelvic area. I would highly recommend this test for all high risk patients.
If anyone needs information or contact numbers please e mail me.
I see my oncologist on Monday to develop a treatment plan. Right now I'm leaning for 6 months of ADT3 then rebiopsy the area. From the MRI and color doppler I have a good picture of the tumor and can see if it changed or disappeared. I can then continue on ATD3 or get IMRT; I'll make that decision based on the color doppler and biopsy. I've pretty much eliminated surgery because of the long term side affects and the high probability that surgery can't get all the tissue.
All in all good news.

I had a psa of 4.4 in 1999 and steadily increasing psa every 3-6 months before reaching 40 in 5-08.Free psa ranged from 16 to 10%

I had biopsies every year, 13 total in all. I saw 5 different doctors, all urologists or urological oncologists at Long Beach, UCLA, UCSF and UCI and had an MRIS at UCSF in 2007. All tests were negative and I was told that because of all the biopsies I most likely didn't have PC, but to keep getting biopsies every year.

in Oct 08 my 13th biopsy of 25 cores indicated 2 positive cores, gleason 3+3 less that 5% in 2 cores. Doc recommended surgery.

2nd opinion from a prostate oncologist, referred by my wife's oncologists said cancer found wis indolant and statistacally insignificant, but PSA histor was a major concern and ordered a few more tests.

Color Doppler ultrasound with targeted biopsy found a transition zone tumor 18mmX16mm, gleason 3+4 and 4+3. CT and bone scans clear, but Doc thinks that there may be lymph node involvement (30% chance) because of my high PSA, and referred me for a Combidex MRI in Holland, currently scheduled for Feb 14.

Changed diet and takiing supplements while I wait. The location of the tumor plus the high psa make surgery an unlikely option. I'm still evaluatiing all treatment options and will make a decision once I get the results of the Combidex scan.


Elite Member

Date Joined Oct 2008
Total Posts : 25382
   Posted 2/20/2009 3:00 PM (GMT -6)   
John, sounds like your trip and extra testing will pay off for you and your case. I hope it works that way for you, and then you can have a plan set to start treatments. Wishing you the best, brother.

Age 56, 56 at DX, PSA 7/7 5.8, 7/8 12.3
3rd Biopsy 9/8 Positive 7 of 7 cores pos, 40-90%, Gleason 7
Open RP surgery 11/14/8, Right nerves saved, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
Post-surgery Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsular, clear margins, clear lymph nodes 
First PSA Post Surgery   2/9 .05

Veteran Member

Date Joined May 2008
Total Posts : 1010
   Posted 2/20/2009 4:59 PM (GMT -6)   

Hi John,

Thanks for the continuing post on your Combidex experience. It appears that it has had a distinct impact on your choice for treatment.

Best of luck to you in the future.


Diagnosed 04/10/08 Age 58 at the time
Gleason 4 + 3
DRE palpable tumor on left side
100% of 12 cores positive for PCa range 35% to 85%
Bone scan clear and chest x ray clear
CT scan shows potential lymph node involvement in pelvic region
Started Casodex on May 2 and stopped on June 1, 2008
Lupron injection on May 15 and every four months for next two years
Started IMRT/IGRT on July 10, 2008. 45 treatments scheduled
First 25 to be full pelvic for a total dose of 45 Gray to lymph nodes.
Last 20 to prostate only. Total dose to prostate 81 Gray.
Completed IMRT/IGRT 09/11/08.
PSA 02/08 21.5 at diagnosis
PSA 07/08 .82 after 8 wks of hormones
PSA 10/08 .642 one month after completion of IMRT, 6 months hormone

Veteran Member

Date Joined Dec 2008
Total Posts : 3149
   Posted 2/20/2009 7:50 PM (GMT -6)   
John, thanks for the update and letting others know such things. Look at the price of their Combidex vs. the MRIS endorectal coil (UCSF) and not only that, but the Combidex trumped the findings completely.
Interesting journey you are taking to say the least and being proactive and questioning everything, you already reflected the multiple opinions thing prior......which was very similar to my journey with the multiple opinions, mind blowing when you are witnessing the whole journey. Hats off to your pioneering journey for others to look at or consider.

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