My ex-boss asked me an interesting PC related question the other day, I couldn't answer it, nor could I easliy find an answer, so I throw it out here. He said, if it's normal for men without PC to have PSA scores all their lives, ranging from .5 to 4.0, which was the threshold for getting a biopsy, and they never get PCa, then how come after someone like me that had surgery, or someone that had radiation or whatever treatment comes back with low amounts of PSA, and its a bad thing. His point was, if its normal for a man to register PSA without having PC, then how can the small or trace amounts ever be dangerous?
The answer may be simple, and I never seem to get the obvious, but his question stumped me, so come help me out here brothers/sisters! I told him I would ask you guys for a straight answer.
David in SC
56, 56 at DX, PSA
7/7 5.8, 7/8 12.3
3rd Biopsy 9/8 Positive 7 of 7 cores pos, 40-90%, Gleason 7
Open RP surgery 11/14/8, Right nerves saved, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
Post-surgery Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsular, clear margins, clear lymph nodes
First PSA Post Surgery 2/9 .05