Some of you may remember that my husband was put on Vesicare last week to help with his bladder urges. The drug did seem to help him except he began experiencing heart palpitations the first day and has decided to stop the drug pending a call to his urologist today. I'll let you know what the doctor has to say.

---

Husband diagnosed in February 2008 (age 57). Cancer discovered during routine annual physical. Clinical Stage T1c, Gleason 7 (3+4), with 2 out of 10 cores testing positive. Perineural invasion identified on biopsy. DRE was negative.

Robotic surgery in March 2008. Pathological stage upgraded to T3a, Gleason still 7 (3+4). Miniscule invasion into prostate capsule but no cancer found outside capsule (surgical margins and seminal vesicles were clean).

1st PSA 3 weeks post op: 0.1; 2nd PSA 7 weeks post op: 0.0. PSA remains at 0.0, and will continue to be checked every 3 months for the first 2 years due to capsular penetration.

Currently on Vesicare to control frequency of urination and on Viagara for ED issues. Recuperation from surgery was uneventful.

Doctor told hubby to discontinue Vesicare and we'll try Enablex which says it doesn't effect the heart. Doctor also said that he's not heard of heart palpitations with Vesicare but that doesn't mean that the drug won't cause these problems. We'll be starting the Enablex tomorrow ... will keep you all posted.

---

Husband diagnosed in February 2008 (age 57). Cancer discovered during routine annual physical. Clinical Stage T1c, Gleason 7 (3+4), with 2 out of 10 cores testing positive. Perineural invasion identified on biopsy. DRE was negative.

Robotic surgery in March 2008. Pathological stage upgraded to T3a, Gleason still 7 (3+4). Miniscule invasion into prostate capsule but no cancer found outside capsule (surgical margins and seminal vesicles were clean).

1st PSA 3 weeks post op: 0.1; 2nd PSA 7 weeks post op: 0.0. PSA remains at 0.0, and will continue to be checked every 3 months for the first 2 years due to capsular penetration.

Currently on Vesicare to control frequency of urination and on Viagara for ED issues. Recuperation from surgery was uneventful.

Thanks for the update, Sephie.  I'm sorry the first drug didn't work out and would be interested in what the second one does.  My detrol LA doesnt' work as well as I had hoped but it probably did help some.  Always looking for something better.  Trust you are both doing well otherwise.  David

---

Age 55

Diagnosed Dec 2007 during annual routine physical

PSA doubled from previous year from 1.5 to 3.2

12 biopsies - 2 positive with 2 marginal

Gleason 3 + 3 = 6

RRP 4 Feb 08

Both nerves spared

Good pathology - no margins - all encapsulated - Gleason 4 + 3 = 7

Catheter out Feb 13 - wore pad for couple of days - pad free Feb 16

Great wife and family who take very good care of me

Steve: He's just starting the Viagra - our insurance company will only cover 4 pills for 20 days but the doctor said to only take it 2 or 3 times each week. Since he hadn't yet taken the pills, the Viagra did not cause the heart palpitations. He starts the Viagara this week with the Enablex so we'll see how everything goes.

Last night, we discussed his fluid intake and being aware of when he needs to stop drinking so that he can make the trip home in more comfort. This morning, he was very proud of himself: only urinated once in 90 minutes after getting up - for him, that's a record! I would prefer that he not take the Enablex long term so we'll see what the drug does and how he fares by restricting his fluid intake at certain times of the day.

Other than that, he's doing great...walking a couple of miles each day plus getting ready for tennis season (which he loves).

---

Husband diagnosed in February 2008 (age 57). Cancer discovered during routine annual physical. Clinical Stage T1c, Gleason 7 (3+4), with 2 out of 10 cores testing positive. Perineural invasion identified on biopsy. DRE was negative.

Robotic surgery in March 2008. Pathological stage upgraded to T3a, Gleason still 7 (3+4). Miniscule invasion into prostate capsule but no cancer found outside capsule (surgical margins and seminal vesicles were clean).

1st PSA 3 weeks post op: 0.1; 2nd PSA 7 weeks post op: 0.0. PSA remains at 0.0, and will continue to be checked every 3 months for the first 2 years due to capsular penetration.

Currently on Vesicare to control frequency of urination and on Viagara for ED issues. Recuperation from surgery was uneventful.