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Sephie
Veteran Member


Date Joined Jun 2008
Total Posts : 1804
   Posted 2/23/2009 8:31 AM (GMT -6)   
Some of you may remember that my husband was put on Vesicare last week to help with his bladder urges. The drug did seem to help him except he began experiencing heart palpitations the first day and has decided to stop the drug pending a call to his urologist today. I'll let you know what the doctor has to say.
Husband diagnosed in February 2008 (age 57). Cancer discovered during routine annual physical. Clinical Stage T1c, Gleason 7 (3+4), with 2 out of 10 cores testing positive. Perineural invasion identified on biopsy. DRE was negative.

Robotic surgery in March 2008. Pathological stage upgraded to T3a, Gleason still 7 (3+4). Miniscule invasion into prostate capsule but no cancer found outside capsule (surgical margins and seminal vesicles were clean).

1st PSA 3 weeks post op: 0.1; 2nd PSA 7 weeks post op: 0.0. PSA remains at 0.0, and will continue to be checked every 3 months for the first 2 years due to capsular penetration.

Currently on Vesicare to control frequency of urination and on Viagara for ED issues. Recuperation from surgery was uneventful.


Steve n Dallas
Veteran Member


Date Joined Mar 2008
Total Posts : 4834
   Posted 2/23/2009 8:44 AM (GMT -6)   

Know the Side Effects of VESIcare

You should know the common side effects of any medicine you take. These are the most common side effects of VESIcare:

  • Dry mouth.
  • Constipation.
  • Blurred vision.
  • Indigestion.

Tell your doctor if you have any side effects that bother you or that do not go away. These are not all the side effects associated with VESIcare. For more information, ask your doctor, healthcare professional, or pharmacist.

http://www.vesicare.com/learn-about-vesicare/know-the-side-effects-of-vesicare.html

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Age 53   - 5'11"   205lbs
Overall Heath Condition - Good
PSA - July 2007 & Jan 2008 -> 1.3
Biopsy - 03/04/08 -> Gleason 6 
 
06/25/08 - Da Vinci robotic laparoscopy
Catheter in for five weeks.
Dry after 3 months.
 
10/03/08 - 1st Quarter PSA -> less then .01
01/16/09 - 2nd Quarter PSA -> less then .01
Surgeon - Keith A. Waguespack, M.D.
 


Sephie
Veteran Member


Date Joined Jun 2008
Total Posts : 1804
   Posted 2/24/2009 4:32 PM (GMT -6)   
Doctor told hubby to discontinue Vesicare and we'll try Enablex which says it doesn't effect the heart. Doctor also said that he's not heard of heart palpitations with Vesicare but that doesn't mean that the drug won't cause these problems. We'll be starting the Enablex tomorrow ... will keep you all posted.
Husband diagnosed in February 2008 (age 57). Cancer discovered during routine annual physical. Clinical Stage T1c, Gleason 7 (3+4), with 2 out of 10 cores testing positive. Perineural invasion identified on biopsy. DRE was negative.

Robotic surgery in March 2008. Pathological stage upgraded to T3a, Gleason still 7 (3+4). Miniscule invasion into prostate capsule but no cancer found outside capsule (surgical margins and seminal vesicles were clean).

1st PSA 3 weeks post op: 0.1; 2nd PSA 7 weeks post op: 0.0. PSA remains at 0.0, and will continue to be checked every 3 months for the first 2 years due to capsular penetration.

Currently on Vesicare to control frequency of urination and on Viagara for ED issues. Recuperation from surgery was uneventful.


Steve n Dallas
Veteran Member


Date Joined Mar 2008
Total Posts : 4834
   Posted 2/24/2009 4:47 PM (GMT -6)   
Is he still on Viagara? That stuff is pretty powerful.

Age 54   - 5'11"   205lbs
Overall Heath Condition - Good
PSA - July 2007 & Jan 2008 -> 1.3
Biopsy - 03/04/08 -> Gleason 6 
 
06/25/08 - Da Vinci robotic laparoscopy
Catheter in for five weeks.
Dry after 3 months.
 
10/03/08 - 1st Quarter PSA -> less then .01
01/16/09 - 2nd Quarter PSA -> less then .01
Surgeon - Keith A. Waguespack, M.D.
 


CPA
Veteran Member


Date Joined Feb 2008
Total Posts : 655
   Posted 2/24/2009 6:54 PM (GMT -6)   
Thanks for the update, Sephie.  I'm sorry the first drug didn't work out and would be interested in what the second one does.  My detrol LA doesnt' work as well as I had hoped but it probably did help some.  Always looking for something better.  Trust you are both doing well otherwise.  David

Age 55
Diagnosed Dec 2007 during annual routine physical
PSA doubled from previous year from 1.5 to 3.2
12 biopsies - 2 positive with 2 marginal
Gleason 3 + 3 = 6
RRP 4 Feb 08
Both nerves spared
Good pathology - no margins - all encapsulated - Gleason 4 + 3 = 7
Catheter out Feb 13 - wore pad for couple of days - pad free Feb 16
Great wife and family who take very good care of me


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 2/24/2009 6:57 PM (GMT -6)   
Sephie, it was wise to stop taking the first one for sure, hopefully, he will get the good results needed on the second drug.

David in Sc
Age 56, 56 at DX, PSA 7/7 5.8, 7/8 12.3
3rd Biopsy 9/8 Positive 7 of 7 cores pos, 40-90%, Gleason 7
Open RP surgery 11/14/8, Right nerves saved, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
Post-surgery Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsular, clear margins, clear lymph nodes 
First PSA Post Surgery   2/9 .05
 
 


Sephie
Veteran Member


Date Joined Jun 2008
Total Posts : 1804
   Posted 2/25/2009 8:36 AM (GMT -6)   
Steve: He's just starting the Viagra - our insurance company will only cover 4 pills for 20 days but the doctor said to only take it 2 or 3 times each week. Since he hadn't yet taken the pills, the Viagra did not cause the heart palpitations. He starts the Viagara this week with the Enablex so we'll see how everything goes.

Last night, we discussed his fluid intake and being aware of when he needs to stop drinking so that he can make the trip home in more comfort. This morning, he was very proud of himself: only urinated once in 90 minutes after getting up - for him, that's a record! I would prefer that he not take the Enablex long term so we'll see what the drug does and how he fares by restricting his fluid intake at certain times of the day.

Other than that, he's doing great...walking a couple of miles each day plus getting ready for tennis season (which he loves).
Husband diagnosed in February 2008 (age 57). Cancer discovered during routine annual physical. Clinical Stage T1c, Gleason 7 (3+4), with 2 out of 10 cores testing positive. Perineural invasion identified on biopsy. DRE was negative.

Robotic surgery in March 2008. Pathological stage upgraded to T3a, Gleason still 7 (3+4). Miniscule invasion into prostate capsule but no cancer found outside capsule (surgical margins and seminal vesicles were clean).

1st PSA 3 weeks post op: 0.1; 2nd PSA 7 weeks post op: 0.0. PSA remains at 0.0, and will continue to be checked every 3 months for the first 2 years due to capsular penetration.

Currently on Vesicare to control frequency of urination and on Viagara for ED issues. Recuperation from surgery was uneventful.


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 2/25/2009 9:43 AM (GMT -6)   
Serphie, was glad to hear that your husband is doing better. Gee, walking 2 miles and playing tennis, I need to get on the ball here.
Age 56, 56 at DX, PSA 7/7 5.8, 7/8 12.3
3rd Biopsy 9/8 Positive 7 of 7 cores pos, 40-90%, Gleason 7
Open RP surgery 11/14/8, Right nerves saved, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
Post-surgery Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsular, clear margins, clear lymph nodes 
First PSA Post Surgery   2/9 .05
 
 

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