It appears you are catching it early and that is in your favor. On the other hand an 80% and 40% sample would indicate some possible substantial growth. It also appears your rising PSA would indicate growth as well. There are many opinions about
all of this, but of course it is your life - as you know.
You are in the right place to do a lot of research and reading. There are many links from this sight as well as experienced and helpful people with a lot of savy about
prostate cancer. No one can tell you what to do, but with a Gleason 6 and the biopsy you described you have some time to consider all the alternatives, but I would not wait too long. Admittedly, I don't have a track record for watching and waiting - I did not have that option. I am not sure how viable your option is in that regard. The blessing of catching these things early and treating them early is the best long term hope - I believe. Besides, for me the most difficult time mentally was making my decision. Once that was made things improved. I wish you well.
Age 61 (now 62)
Original data - pre-operation
T1C clinical diagnosis, Needle biopsy - 10 cores, Gleason 7 = 3+4 in 1 core (40%), 7 cores Gleason 6 = 3+3 ranging from 5% to 12%
All scans negative
Lupron administered 4/9/2008 for 4 months (with idea I would undergo external beam radiation followed by seed implants - then I changed my mind).
Robotic DiVinci surgery - Dr. Fagin (Austin) May 19th
Post operative - pathology
pT2c NX MX
Margins - negative
Extraprostatic extension - negative
seminal vesicle invasion - uninvolved
1st Post PSA <.04
2nd Post PSA <.01 10/30/2008