From everything I have read, IADT is more effective as you can continue it for a longer period as the PC cells stay androgen dependent longer and the quality of life issues are better during the periods you are off it. I hope he is on Casodex and Proscar along with the Lupron as it is more effective and Proscar is still taken during the off periods as it slows the PSA rise.
Weight training and excercise is essential he will lose muscle and bone during the treatments. Weight training will nulify this, also take calcium citrate for bone loss.
I would highly recommend that you consult with a prostate oncologist, there is a good list on the PCRI web site. They know a lot more about
the biology of cancer and can adjust medications and tell when the hormones have stopped doing their magic. Even if you have to travel to see a good oncologist your current urologist can still give the treatments locally. The oncologist will act as your personal consultant.
A must read is "Beating Prostate Cancer; Hormone therapy and diet" by dr Charles Snuffy Myers. There are also free videos on the PCRI web sit from Dr Sholtz and Dr Lam that are worth viewing.
Hormone Therapy has proven effective in controlling PC for many years and hopefully there will be more advancements in the next few years that will help. Good luck.
64 years old.
I had an initial PSA test in 1999 of 4.4. PSA increased every 6 months reaching 40 in 5-08. PSA free ranged from 16% to 10%. Over this time period I had a total of 13 biopsies and an endorectal MRIS all negative and have seen doctors at Long Beach, UCLA, UCSF and UCI. DX has always been BPH and continue to get biopsies every year.
In 10-08 I had a 25 core biopsy that showed 2 cores positive, gleason 6 at less than 5%. Surgery was recommended and I was in the process of interviewing surgeons when my wife's oncologist recommended I get a 2nd opinion from a prostate oncologist.
I saw Dr Sholtz, in Marina Del Rey, and he said that the path reports indicated no tumor, but indolant cancer clusters that didn't need any treatment. He was concerned that my PSA history indicated that I had a large amount of PC somewhere that had yet to be uncovered and put me through several more tests.
A color doppler targeted biopsy in 11-08 found a large tumor in the transition zone, gleason 6 and 7. Because of my high PSA Dr. suspected lymph node involvement, 30% chance, and sent me to Holland for a Combidex MRI, even though bone and CT scans were clear.
Combidex MRI showed clear lymph nodes and a 2,5 cm tumor in the anterior. I was his 1st patient to come up clear on the Combidex which has a 96% accuracy,
I've been on a no meat and dairy diet since 12-08 and PSA reduce to 30 while I awaited the Combidex MRI.
The location of the tumor in the anterior apex next to the urethea makes a good surgical margin very unlikely. Currently on Casodex and Proscar for 8 weeks to shrink my 60 mm prostate. Treatment will be seeds followed by 5 weeks of IMRT while continuing on Casodex and Proscar. So far no side affects from the Casodex.