I am a new member with a question to put out there---is it better to go with continuous hormone therapy (ADT) or intermittent (IADT)? Want to thank everyone for all the great info and support as it has really helped as we go through our journey beating PCa! I'm the wife/advocate for my husband, a 14 yr PCa survivor!
History should hopefully appear below if I did the signature right---but in a nutshell, Jimmy had RP in 1995, then EBR in 1998 (PSA began rising), then hormone therapy was begun in 2000 after a significant rise from 1.3 to 3.6 in 3 months) and he has had continuous LUPRON inj. up to the present successfully keeping PSA < .1! As for treatment side effects,is still continent (some accidents, but mostly ok) but impotent which is to be expected and has generally tolerated all well. (no hot flashes, that's my department!) As for the impotence, we would not have made any other decision and have no regrets.....we had a great sex life prior to PCa but have learned a lot along the way & have become more intimate in other ways-communication is definitely the key as some of you have already said. The main difference now (with hormone treatment) and BHT(before hormone therapy--my made up abrev) is that before he did have desire but was frustrated about performance so tried different things such as viagra...now with hormone therapy desire is gone, thus the frustration is gone also. So I feel this is a good thing(not sure this is also his view). We are still on this journey together, but we are hugging and holding hands a lot more!
Back to question--since Jimmy, now 65 & retiring from coaching/teaching is also promising to take a more active role in his health (weighs>300 lbs, has high blood pressure-controlled, is a candidate for type II diabetes) Through this forum I have connected to some wonderful links and learned alot (THANKS!)-Dr Gerry Chodak (great videos---I encourage everyone to go look as you can watch specific ones that pertain to your state in this battle) and the Prostate Cancer Research Institute site (see the PCRI 2008 Conference-I learned a lot about trials concerning our interest in intermittent vs. continuous ADT in the talk by Dr. S Strum) to name a few. I have not listed specific links as I am not sure if it is allowed or has to be approved by moderators (maybe you moderators can give me a heads up on this) Sooo, thru these sites I have learned that there are studies out there showing cont. ADT has some harmful side effects---such as bone loss, incr. risk of diabetes, loss of muscle, impotence, affects to cognitive function...to name a few, so for that reason there are studies showing IADT should be the way to go. It gives the body a rest so to speak--a time for some QOL benefits, and if I'm reading the info out there correctly, they have absolutely no evidence that there is any difference between ADT & IADT as to life expectancy. We will be discussing this with our uro (who happens to be a friend in whom Jimmy has tremendous confidence), but I was wondering if we should also consult an expert oncologist---? Any response, advise, etc. would sure be appreciated..Did not mean to write so much..Thanks for all of your work and inspiration! To those of you out there beginning or further along in this journey, don't get discouraged even if PSA rises...as long as you keep informed there is constantly being new info published showing that PCa can be beat!!