Changing PSA LAB ?

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flippin out
Regular Member

Date Joined Mar 2006
Total Posts : 137
   Posted 3/27/2009 11:44 AM (GMT -6)   
Going from the sensitive to the not so sensitive after radiation PSA testing
what might one expect?
50 Diagnosed as type II Diabetic
54 Cancer Detected
55 Da Vinci City Of Hope California
57 Cancer rise in successive PSA's
57 Radiation Loma Linda Medical Center California

Regular Member

Date Joined Aug 2007
Total Posts : 118
   Posted 3/27/2009 2:10 PM (GMT -6)   
What is your reason for changing labs? Are you concerned about seeing fluctions in the ultrasensitive test, or do you need to change labs for insurance or geographical reasons? If you search my postings, you will see that I have asked this question on several occasions, however I have only had surgery. My personal reason for the consideration of a new lab and "conventional" PSA test is to reduce anxiety. I had a very good surgical outcome with a very low chance of recurrence and saw little benefit from seen ultrasensitive fluctions. However, I am not familiar with monitoring PSA after radiation. You will want the opinions of others on this.
Age:45 (44 when diagnosed)
Father diagnosed and cured at age 52.
08/21/07: Diagnosed with T1c cancer
1 of 12 biopsy cores positive; 10% tissue
Gleason score: 3+3=6
PSA level prior to biopsy: 4.3 (velocity < 0.4ng/ml)
10/19/07: da Vinci prostatectomy by Dr. Vipul Patel
              Difficult surgery due to prostate inflammation.
              Both nerve bundles spared.
              Spongy erections began within 24hrs of surgery!
10/24/07: Catheter out; down to 1 Serenity pad/day next day.
              Final pathology: neg margins, no capsular penetration,
              Gleason 3+3=6, 5% tumor involvement, multi-focal.
11/04/07  First usable erection with Cialis
11/22/07  Thanksgiving - Bye-bye, pads
01/17/08  First post-surgery PSA result: < 0.008 ng/ml
03/17/08  Erection quality mostly back to pre-surgery levels with Cialis;
              have not tried without meds yet.
04/23/08  Second post-surgery PSA result: < 0.008 ng/ml
07/30/08  Third PSA: 0.01 ng/ml
11/04/08  One year PSA: 0.01
              Still taking 10mg Cialis every other day - enjoying the results
              too much to stop yet.
02/07/09  Taking 5mg Cialis every other day - having too much fun to try
              to stop for now.
03/23/09  PSA: 0.02

Veteran Member

Date Joined Jul 2006
Total Posts : 686
   Posted 3/27/2009 5:44 PM (GMT -6)   
mjr said...
Going from the sensitive to the not so sensitive after radiation PSA testing
what might one expect?

I was required to change labs due to HMO change.  Neither lab was considered "ultra sensitive".  As you can see my PSA went up slightly.  The doctor said "undetecable is undetecable". don't worry.

PSA up to 4.7 July 2006 , nodule noted during DRE
Biopsy 10/16/06 ,stageT2A
Aggressive Gleason 4+4=8  right side
DaVinci Surgery  January 2007
Post op confirms gleason 4+4=8
No extension or invasion identified
Few continence problems
PSA 90 day (-.01)  , (6 month -.01) , (9 month +.02) , (1 year +.02) ( 18 months +.02) (two years+.03)
One side nerve spared
success but some plaque with bimix 
born in 1941

Post Edited (lifeguyd) : 3/27/2009 4:48:08 PM (GMT-6)

Steve n Dallas
Veteran Member

Date Joined Mar 2008
Total Posts : 4849
   Posted 3/28/2009 5:47 AM (GMT -6)   
One problem with second opinions is that if the results are different - you need to get a third opinion...
Age 54   - 5'11"   205lbs
Overall Heath Condition - Good
PSA - July 2007 & Jan 2008 -> 1.3
Biopsy - 03/04/08 -> Gleason 6 
06/25/08 - Da Vinci robotic laparoscopy
Catheter in for five weeks.
Dry after 3 months.
10/03/08 - 1st Quarter PSA -> less then .01
01/16/09 - 2nd Quarter PSA -> less then .01
Surgeon - Keith A. Waguespack, M.D.

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