Hi Maritza...I can answer a couple
Perineural Invasion is quite common on pathology. So common most pathologist won't mention it. Nothing to worry about
Tumor Multicentricity Sorry not sure on that one. I know that prostate cancer is multifocal...but don't think this means the same thing.
High Grade PIN This is somewhat common. Typically it is precancerous or benign tumor and sometimes thought it would lead to cancer if found on biopsy
Stage pT2cN0MX is just the staging of the cancer. There are 4 stages 1 ~ 4 with 4 being the most advanced. The N0 means that no lymph node involvement which is good. MX refers to mets that wasn't indicated. Generally the bone scan would detect or if for some reason the cancer has moved to other organs. You usually require additional test for mets. So the path won't report that.
Over all it sounds like the path report was a good one.
Someone else will chime in on the tumor multicentricity
You are beating back cancer, so hold your head up with dignity
Age 58 at Diagnosis
Oct 2006 - PSA 2.6 - DRE Normal
May 2008 - PSA 4.6 - DRE Normal / TRUS normal-Gland 38 cc
July 2008 - Biopsy 4 of 12 Positive 5 - 30% Involved Bilateral (Perineural Invasion present at base) - Gleason (3+3) 6 Stage T1C
August 23 - Bone Scan - Hips, Spine and ribs marked uptake - X-Ray showed clear -Hooray
Sept 9 2nd DRE - questionable - TRUS...shadow in base - Gland now 41 cc
Robotic Surgery Sept 18, 2008
Pathology October 1, 2008 - Gleason 7 (4+3) Staged pT2c NO MX - Gland 50 cc
Seminal Vesicles and Lymph Nodes clear
Positive Margins Right Posterior Lobe
4 tumors in prostate - largest being 6 cm
PSA 5 week Oct 2008 <.05
3 month Jan 2009 .06