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Regular Member

Date Joined Oct 2007
Total Posts : 300
   Posted 4/4/2009 3:45 PM (GMT -6)   
I am about 15 months post-op.  All my PSA's have been undetectable up to the 1 year mark.  At one year the PSA was .11. Retested a month later at original lab .09.  Saw my Uro last week, he wants me to retest again in May. I already set up a consultation with a Rad Oncologist this month prior to the test.   Am I over-reacting?  Has anyone else post RRP had a rise at the 1 year mark only to go back down after a couple of months.  I had one positive margin so I am very concerned.  This darn PSA anxiety just never goes away.
Age 65
Diagnosed 10/12/07
PSA 6.3
Biopsy 18 core samples, 2 positive <5%
Stage T1a Gleason 6 (3+3)
LRP  1/29/08
Gleason 7 (3+4)
1 positive margin (.3cm)
4/16/08- Started Bi-mix injections 
5/15/08- 1st Post-Op PSA 0.07 Undetectable
8/11/08 -2nd Post-OP PSA 0.02 Undetectable
8/15/08- No more pads as of today  Whoopee!!!
11/13/08- 3rd post-op PSA 0.02 Undetectable
03/02/09- 1 yr. post-op PSA .09 Undetectable

Ed C. (Old67)
Veteran Member

Date Joined Jan 2009
Total Posts : 2460
   Posted 4/4/2009 6:51 PM (GMT -6)   
I always thought the 0.1 or leas is considered undetectable, so your 0.09 is still considered to be a zero.
Age: 67
Retired in 2001 and living in Austin TX.
PSA 9/05 1.15; 8/06 1.45; 12/07 2.41; 8/08 3.9; 11/08 3.5 free PSA 11%
Dx 12/30/08
2 cores out of 12 were positive Gleason (4+4) and (4+5)
Negative CT scan and bone scan done on 1/16
Robotic surgery performed 2/9/09
Surgeon: Dr. Randy Fagin, Austin TX.
Post op Pathology report:
Prostate weighed 57 grams
size:5.2 x 5.0 x 4.9 cm
Bilateral 10-20% involved
Gleason 4+4
both nerve bundles removed,
pT3a Nx Mx
Negative margins
Lymph nodes: not dissected
seminal vesicles clean

Ralph Alfalfa
Regular Member

Date Joined Nov 2008
Total Posts : 469
   Posted 4/4/2009 7:49 PM (GMT -6)   
When I had my PSA done last, the Uro explained to me that it may go, as it did for another of his patients, from .01. to .04 up to .08, and then decline from there. He said it was nothing to worry about. NOt that .08 was the high point, but you could possibly have a jump and then a fallback. I wouldn't worry. Stay well.
 Dx: October,27(the day after my birthday)
 Psa 14.5
 Gleason:(4+3) 7 T1c
 Bone scan:Negative
 Cat scan: Negative
 Biopsy: 4 of 12 positive, left side, pre-cancerous on the right.
 Confined to prostate.
 DaVinci Jan. 19th, No lymph node involvement, all margins clear.
 8 week PSa <0.01
 Gleason downgraded to (3+4)7
 Fully continent...ED progressing as expected.

Veteran Member

Date Joined Oct 2006
Total Posts : 1211
   Posted 4/4/2009 8:12 PM (GMT -6)   
Hi Bootheel,

As you can see by my signature, my PSA started to climb about 12 month after my RRP. Unlike yours, mine never went down and when it reached .08 my Uro , my Onc and I, decided that some cancer cells were probably left behind and it was time to attack and try to destroy them. Apparently, the sooner the RT is started after PSA increase, the better the chance of destroying remaining cancer cells.
By the time my RT started. the PSA had reached .1. Six weeks after the end of RT the PSA was down to .05 and we hope that it will continue to go down further or at least stay in the 'undetectable' region. I would keep a very close eye on the PSA level when it looks as if it maybe going up and take action sooner rather than later.
Good luck and all the best to you in the years to come.

Born Sept 1936
PSA 7.9
-ve DRE
Gleason's Score 3+4=7, 2 of 8 positive
open RP 28 Nov 06 (nerve sparing), Post op staging T3a
Gleasons still 3+4=7
Seminal vesicles and lymph nodes clear
Catheter out 15 Dec 06, Dry since 11 Feb 07
All PSA tests in 2007 (4) <.04
PSA tests in 2008: Mar.=.04; Jun.=.05; Sept.=.08; 3 days before Rad Start=0.1
Salvage RT completed (33 sessions - 66 Grays) on the 19th Dec., 08.
PSA on the 26 Jan., 09, =0.05. PSA tests now every 6 month

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