My First PSA after surgery

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texican
Regular Member


Date Joined Jan 2009
Total Posts : 36
   Posted 4/6/2009 12:48 PM (GMT -6)   
Good news for me today. My first PSA after surgery was 0.01, the lowest the equipment can measure. My surgeon says we have to keep watching this every 3-4 months for the next couple of years. My pre-surgery PSA was over 30 for the past few years even though the biopsies did not show cancer until the last one.

The area of concern was the grading (7) and positive margin. He likened the positive margin to a situation where you are trying to round up a hive of bees. You got them all except one that is somewhere out there flying around. Chances are it won't survive without the queen. At least that is the hope.

John
Dx December 22, 2008
Age 69
PSA 1998 5.2, 2000 2.5, 2003 5.4, 2004 7.4, 2005 15.9, 2006 20.5, 2007 31.5, 2008 34 and 32.9
Biopsy 1998-no cancer, 2003 - no cancer, 2006 - 12 samples, no cancer but PIN, Dec. 2008 - 12 samples, 2 positive with Gleason 4+3 = 7 on each. PIN on 3 others.
Di Vinci surgery on 2/10/2009, Austin TX
Pathology post surgery T3a, Gleason (4+3)7 with tertiary pattern 5.
NX,MX,R1, margin involvement 1-2 mm
Catheter removed on February 23.
First PSA followup on April 6, 2009 with 0.01 (lowest they can measure)


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 4/6/2009 1:33 PM (GMT -6)   
Congrats to you on your first big Zero, may you have many long years of those ahead of you. And yeah, let's hope that last stray bee is long dead and gone.

David in SC
Age 56, 56 at DX, PSA 7/7 5.8, 7/8 12.3,9/8 14.5
3rd Biopsy Sept 08: Positive 7 of 7 cores, 40-90%, Gleason 7, 4+3
Open RP surgery 11/14/8, Right nerves spared, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
Post-surgery Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsular, clear margins, clear lymph nodes 
First PSA Post Surgery   2/9 .05, 6 month on 5/9
 
 


Steve n Dallas
Veteran Member


Date Joined Mar 2008
Total Posts : 4834
   Posted 4/6/2009 1:42 PM (GMT -6)   
Welcome to the ZERO Club.

Age 54   - 5'11"   205lbs
Overall Heath Condition - Good
PSA - July 2007 & Jan 2008 -> 1.3
Biopsy - 03/04/08 -> Gleason 6 
 
06/25/08 - Da Vinci robotic laparoscopy
Catheter in for five weeks.
Dry after 3 months.
 
10/03/08 - 1st Quarter PSA -> less then .01
01/16/09 - 2nd Quarter PSA -> less then .01
Surgeon - Keith A. Waguespack, M.D.
 


CPA
Veteran Member


Date Joined Feb 2008
Total Posts : 655
   Posted 4/6/2009 3:33 PM (GMT -6)   
Zero is great news.  Here is hoping that this is the first of many.  David

Age 55
Diagnosed Dec 2007 during annual routine physical
PSA doubled from previous year from 1.5 to 3.2
12 biopsies - 2 positive with 2 marginal
Gleason 3 + 3 = 6
RRP 4 Feb 08
Both nerves spared
Good pathology - no margins - all encapsulated - Gleason 4 + 3 = 7
Catheter out Feb 13 - wore pad for couple of days - pad free Feb 16
Great wife and family who take very good care of me


Ralph Alfalfa
Regular Member


Date Joined Nov 2008
Total Posts : 469
   Posted 4/6/2009 7:57 PM (GMT -6)   
Terrific news. John. Welcome to the club and keep those goose eggs coming!
Bob
 AGE:57
 Dx: October,27(the day after my birthday)
 Psa 14.5
 Gleason:(4+3) 7 T1c
 Bone scan:Negative
 Cat scan: Negative
 Biopsy: 4 of 12 positive, left side, pre-cancerous on the right.
 Confined to prostate.
 DaVinci Jan. 19th, No lymph node involvement, all margins clear.
 8 week PSa <0.01
 Gleason downgraded to (3+4)7
 Fully continent...ED progressing as expected.


CaPCa
Regular Member


Date Joined Aug 2007
Total Posts : 118
   Posted 4/6/2009 11:04 PM (GMT -6)   

This is, indeed, good news. I ran across a study indicating that achieving such a low level post surgery was the strongest predictor of relapse-free survival. (Search on "Using PSA Intelligently to Manage Prostate Cancer".) Ultra-low PSA was a stronger predictor than any other variable, e.g. Gleason, margins, pre-op PSA, etc. I don't know if there have been subsequent studies to support or refute this, but it is worth a read.

CaPCa


Age:45 (44 when diagnosed)
Father diagnosed and cured at age 52.
08/21/07: Diagnosed with T1c cancer
1 of 12 biopsy cores positive; 10% tissue
Gleason score: 3+3=6
PSA level prior to biopsy: 4.3 (velocity < 0.4ng/ml)
10/19/07: da Vinci prostatectomy by Dr. Vipul Patel
              Difficult surgery due to prostate inflammation.
              Both nerve bundles spared.
              Spongy erections began within 24hrs of surgery!
10/24/07: Catheter out; down to 1 Serenity pad/day next day.
              Final pathology: neg margins, no capsular penetration,
              Gleason 3+3=6, 5% tumor involvement, multi-focal.
11/04/07  First usable erection with Cialis
11/22/07  Thanksgiving - Bye-bye, pads
01/17/08  First post-surgery PSA result: < 0.008 ng/ml
03/17/08  Erection quality mostly back to pre-surgery levels with Cialis;
              have not tried without meds yet.
04/23/08  Second post-surgery PSA result: < 0.008 ng/ml
07/30/08  Third PSA: 0.01 ng/ml
11/04/08  One year PSA: 0.01
              Still taking 10mg Cialis every other day - enjoying the results
              too much to stop yet.
02/07/09  Taking 5mg Cialis every other day - having too much fun to try
              to stop for now.
03/23/09  PSA: 0.02
 


califguy
Regular Member


Date Joined Sep 2008
Total Posts : 72
   Posted 4/6/2009 11:11 PM (GMT -6)   

Woo Hoo!!!! Yeah for you. I know I certainly breathed a sigh of relief when I got my .01 !!!!! I have had several now and it stays that way.

Keep on keeping on!

 


Don't get discouraged!!
CalifGuy
 
Diagnosed Feb 2008  54 years old
3+4=7 gleason
7.5 PSA
4 out of 20 biopsies were cancerous
daVinci Robotic surgery July 24, 2008  Univ of Calif San Francisco Med Center  Dr Peter Carroll
In hospital 2 nights altho I had option of leaving the next day but stayed due to distance home.
Contained in prostate, not spread
Six weeks post surgery PSA less than .01
Five month PSA less than 0.1  Lab did wrong type of PSA test so this test was not as accurate.
Eight Month PSA less than .01  Yeah!!!!1


NV RTRD 2007
Regular Member


Date Joined Jan 2009
Total Posts : 75
   Posted 4/6/2009 11:30 PM (GMT -6)   
Congrats! What a great feeling to know that you got those zeros. I was so happy and relieved when I had my first post PSA which was <.05. My second post PSA is also the same and hopefully and we all pray that we got zeros everytime our doctor requires us to get post PSA.
Age 54; Age DX 53
PSA: May 07- 2.9; Dec 07-4.3; Jan 2008- 6.1; May 2008- 6.4; Sep 2008- 7.3 ; Sep 2008- 9.6
Bone Scan: Mar 2007- Normal without evidence of metastatic disease.
Biopsy Mar 2008: 6/6 core right gland- No evidence of malignancy; 5/6 core left gland- positive Gleason score 3+3=6 average tumor volume 5 mm.Clinical Stage II.
Transrectal ultrasound at UCSF Jun 2008: 7x14x10 mm hypoechoic lesion in left gland. DRE positive, PSA Density- 0.23 and Prostate volume - 27 CC.
RRP: 4 Dec 2008; Discharged - 8 Dec 2008; Cath removed- 18 Dec 08.
Pathology Report: Prostate- 33 grams; L/R pelvic lymph node -No evidence of malignancy; Right Lobe- No definite tumor; Adenocarcinoma, Gleason 3+4.
Post PSA: 7 Jan 2009 - <.05.
              10 Mar 2009 -<.05


DJBearGuy
Veteran Member


Date Joined Dec 2008
Total Posts : 757
   Posted 4/7/2009 3:59 AM (GMT -6)   
Congratulations!

Liking that bee analogy too. I'll have to remember that.

DJ
Diagnosis at age 53. PSA 2007 about 2; PSA 2008 4.3
Biopsy September 2008: 6 of 12 cores positive; Gleason 4+3 = 7
CT and Bone scan negative
Da Vinci surgery at City of Hope December 8, 2008
Radical prostatectomy and lymph node dissection
Catheter out on 7th day, replaced on 8th day, out again 14th day following negative cystogram
Pathology: pT2c; lymph nodes negative; margins involved; 41 grams, 8% involved by tumor; same Gleason 4+3=7
PSA 1/22/08 non-detectable! 8-)


creed_three
Veteran Member


Date Joined Jan 2007
Total Posts : 762
   Posted 4/8/2009 1:23 AM (GMT -6)   
Hi John,

This is excellent news - so glad to hear of your results. All the very best. Enjoy the moment and the moments to come. Hoping for zeros for you forever. Lana & CJ
Creed_three
Husband 51 yrs (49 years at diagnosis)
PSA (2002) 2.1.  PSA (2006) 3.5.  1 x (5%) core of 12 positive at biopsy. 11 cores negative. Open Radical Prostatectomy with nerve sparing April 2007. Gleeson 3 + 4 = 7.   Undetectable PSA since Surgery (< 0.1) specifically,  
June 2007: 0.01; Oct 2007: 0.02; April 2008: 0.02: October 2008: 0.03: November, 2008 (repeat PSA with instructions to lab to calibrate carefully) = 0.02.
 


James C.
Veteran Member


Date Joined Aug 2007
Total Posts : 4462
   Posted 4/8/2009 8:51 AM (GMT -6)   
Great news, welcome to the club wink
James C. Age 62
Co-Moderator- Prostate Cancer Forum
4/07 PSA 7.6, referred to Urologist, recheck 6.7
7/07 Biopsy: 3 of 16 PCa, 5% involved, left lobe, GS 3/3=6
9/07 Nerve sparing open RRP- Path Report: GS 3+3=6 Stg. pT2c, 110gms, margins clear
16 mts: ED- 50 mg Viagra 3X week, pump daily,Trimix .35ml 2X week continues
PSA's: .04 each 3 months

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