Advice on using trimix

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Ed C. (Old67)
Veteran Member


Date Joined Jan 2009
Total Posts : 2455
   Posted 4/15/2009 4:28 PM (GMT -7)   
Hi,
I have tried the VED pump but I never got a usable erection even with using 2 rings. My doctor prescribed trimix for me which I'll start using soon. He suggested that I should start with the lowest dosage (.01) and see if that works, if not, then I can go up to .02 the following day and so on. Will using the pump or some ED medication in conjunction with trimix help? I've read some posters talking about trimix causing some pain, how long does the pain last? Does trimix work even when no nerves were spared? That a lot of questions but as you can see I'm new at this business.
Age: 67
Retired in 2001 and living in Austin TX.
PSA 9/05 1.15; 8/06 1.45; 12/07 2.41; 8/08 3.9; 11/08 3.5 free PSA 11%
Dx 12/30/08
2 cores out of 12 were positive Gleason (4+4) and (4+5)
Negative CT scan and bone scan done on 1/16
Robotic surgery performed 2/9/09
Surgeon: Dr. Randy Fagin, Austin TX.
Post op Pathology report:
Prostate weighed 57 grams
size:5.2 x 5.0 x 4.9 cm
Bilateral 10-20% involved
Gleason 4+4
both nerve bundles removed,
pT3a Nx Mx
Negative margins
Lymph nodes: not dissected
seminal vesicles clean
1st PSA test 4/7/09 result 0.1


biker90
Veteran Member


Date Joined Nov 2006
Total Posts : 1464
   Posted 4/15/2009 7:57 PM (GMT -7)   
Hey Ed,

I have used Trimix successfully since 8/07 when I was 8 months post surgery. My doc gave me the first injection and showed me how to do it. He gave me .1 cc which was way too much and caused a lot of pain. Over the next several months I experimented with various combinations of L-Arginine (a supplement that enhances blood flow), Viagra (from ADC) and Trimix. My combination that works every time and lasts for about an hour and a half is: 50 mg Viagra, wait a half hour, manually stimulate until plump then inject .03 cc of Trimix. Within 10 minutes of foreplay I am ready to go.

Both my nerves were spared so maybe someone with more experience in that area will jump in here...

Jim
Age 74. Diagnosed 11/03/06. PSA 7.05. Stage T2C Gleason 3+3.
RRP 12/7/06. Nerves and nodes okay.
Catheter out on 12/13/06. Dry on 12/14/06.
Pathological stage: T2C N0 MX. Gleason 3+4.
50 mg Viagra + .04 cc Trimix = Excellent Results
PSAs from 1/3/07 - 7/17/08 0.00.
PSA on 1/28/09 - 0.02
Lung cancer dxed on 5/16/08. Surgery on 6/25/08 T1N1M0 - Stage IIA Finished 4 cycles of chemo on 11/7/08.
CT scans on 12/2/08 & 2/25/09 - in remission!!!
Next scan in May 09.
Biker90's Journey
http://www.caringbridge.org/visit/jimrobinson
"Patience is essential, attitude is everything."


Tamu
Veteran Member


Date Joined Oct 2006
Total Posts : 626
   Posted 4/16/2009 5:53 AM (GMT -7)   
Ed,

The aprostadil portion of the Trimis is what causes the pain. I would characterize it more as an ache instead of pain. I was on Bimix for a while but felt the erections were just not firm enough. I had tried Caverjet which is all aprostadil at the beginning and had severe aching. I read on this forum where some posters were using Trimix but with a lower percentage of Aprostadil then the standard Trimix. Since Trimix is a compounded medication it can be customized. I got a prescription for Trimix using one fourth the amount of Alprostadil then standard. That has worked fine for me and I am still refining the dosage. I am at .10 cc now and still going down in amount. I was using .25 cc of Bimix. I get a little aching with the Trimix. I have combined Levitra and Bimix/Trimix and it does help. Jim has a good plan so give it a try.

Good Luck.

Tamu
Diagnosed 7/6/06, 1 of 10 core samples, 40%,Stage T1c, Gleason 3+3
Da Vinci on 11/01/06, Catheter out on 11/13/06
56 Years Old
Post Op Path, Gleason 3+3, Approx. 5% of prostate involved
Prostate Confined, margins clear
Undetectable PSA on 12/18/06, 6/25/07, 1/8/08
No more pads as of 1/13/07
Began injections in April '07
 


hb2006
Regular Member


Date Joined Nov 2008
Total Posts : 299
   Posted 4/16/2009 7:43 AM (GMT -7)   

Ed

Trimix/Bimix/Caverject/Edex all work with no nerves. The drug causes the blood to rush in and engorge your penis. The aching pain comes from the Aprostadil which doesn't affect some guys, who are extremely lucky as far as I am concerned. You can have a low Libido or no Libido and Aprostadil will work.

I would follow your doctor's advice although I have found that if I miss the correct spot when I inject, I don't wait a day. I simply go to the other side and give myself another injection. However, I'm using really low doses of the Trimix and an extremely small,short needle.

Taking Ibuproven before injecting will help with the pain. I usually take an Advil before I use the syringe. Btw, like others on here, I have found that I'm needing a smaller and smaller dose as time goes by.


Age 60
PSA 2007 4.1
PSA 2008 10.0
Diagnosed April 2008
Biopsy: 6 of 12 cores positive
Gleason 4 + 5 = 9
CT and Bone Scan negative
Open surgery at Shawnee Mission Medical Center May 21, 2008
Right side nerves spared
Radical prostatectomy and lymph node dissection
Cather removed on June 3rd, totally dry on July 9th
pT2c
lymph nodes negative
PSA Sept 28, 2008 0.00
PSA Jan 22, 2009 0.00


Ed C. (Old67)
Veteran Member


Date Joined Jan 2009
Total Posts : 2455
   Posted 4/16/2009 8:31 AM (GMT -7)   
Thank you all for your help. This forum is so helpful in so many ways.
Age: 67
Retired in 2001 and living in Austin TX.
PSA 9/05 1.15; 8/06 1.45; 12/07 2.41; 8/08 3.9; 11/08 3.5 free PSA 11%
Dx 12/30/08
2 cores out of 12 were positive Gleason (4+4) and (4+5)
Negative CT scan and bone scan done on 1/16
Robotic surgery performed 2/9/09
Surgeon: Dr. Randy Fagin, Austin TX.
Post op Pathology report:
Prostate weighed 57 grams
size:5.2 x 5.0 x 4.9 cm
Bilateral 10-20% involved
Gleason 4+4
both nerve bundles removed,
pT3a Nx Mx
Negative margins
Lymph nodes: not dissected
seminal vesicles clean
1st PSA test 4/7/09 result 0.1

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