Sorry you need to be here, but glad you found us. Altogether, based on what you posted, your husband has cancer in 8 out of the 11 cores sampled. The five of five that were 95% is pretty cancerous for sure, but at this point tested to be Gleason 6. The other 3, @ 25%, were Gleason 7. It is always important to remember that the best biopsy is but an estimate of what they think the cancer is at that point in time. Sometimes, the Gleason scores are higher after surgery, because they have the entire prostate to examine, as well as lymph nodes, etc to check. On rare occasions, the Gleason score is lessened after surgery or treatment.
The dr. is probably correct about the cancer being contained at this point, but with the Gleason 7 cores, it doesn't take much for it to move outside the prostate itself. While you have plenty of time to think over treatment decisions, I am sure the dr. wouldn't want your husband to wait too long to decide.
With his biopsy stats, and gleason, and his age, and I am assuming he has no other major medical ailments, I myself would opt for surgery, either robotic or open, with a very experienced surgeon. Surgery before radiation in this case would make much more safe, and be more logical if any cancer cells were on the loose after the fact. Salvage sugery is not a good option in most all cases.
The other advantage to surgery at this point, is that you will more likely know the full extent of his cancer after the post surgical pathology report, and know pretty well if it was or wasn't contained.
In most cases, at this point, and I am not a dr or pretending to be one, the Cat scan/Bone scan should come back clean. With a Gleason 7 in the biopsy, it is very common to run the tests just in case.
I hope only the best for you and your husband, there are many here that will be glad to help, and we are full of experience and advice. Please keep us posted of your travels.
David in SC
Age 56, 56 at DX, PSA 7/7 5.8, 7/8 12.3,9/8 14.5
3rd Biopsy Sept 08: Positive 7 of 7 cores, 40-90%, Gleason 7, 4+3
Open RP surgery 11/14/8, Right nerves spared, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
Post-surgery Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsular, clear margins, clear lymph nodes
First PSA Post Surgery 2/9 .05, 6 month on 5/9