Different individuals have a different affect from ADT. It seems like younger men have a harder time with Lupron. There is no question about
the effectiveness of ATD. It can keep advanced patients alive for quite a number of years.
PAACT recommends 6 months of ADT3 before starting any local treatment, because if it doesn't stop the PC outright it improves the effectiveness of any local treatment.
Liebowitsz presents some stunning cure rates for local PC with high dose ADT3 for 13 months that surpass both surgery and radiation. I guess it's 13 months of hell, but no lasting side affects. There are horror stories about
both surgery and radiation, except that the affects are permanent and not temporary.
I think there are a lot of misconceptions about
Hormone therapy that keep get repeating. I've been on Casodex and Proscar for 3 months and have very few side affects, loss of libido and some minor hot flashes at night that are tolorable. All should disappear when I stop. My PSA has dropped form 30 to 0.6 and prosate volume from 60mm to 32 mm. I had seriously considered 13 months ADT3 for local treatment as an option to radiation.
Compared to Chemo that is given for most other cancers ADT is a breeze.
64 years old.
I had an initial PSA test in 1999 of 4.4. PSA increased every 6 months reaching 40 in 5-08. PSA free ranged from 16% to 10%. Over this time period I had a total of 13 biopsies and an endorectal MRIS all negative and have seen doctors at Long Beach, UCLA, UCSF and UCI. DX has always been BPH and continue to get biopsies every year.
In 10-08 I had a 25 core biopsy that showed 2 cores positive, gleason 6 at less than 5%. Surgery was recommended and I was in the process of interviewing surgeons when my wife's oncologist recommended I get a 2nd opinion from a prostate oncologist.
I saw Dr Sholtz, in Marina Del Rey, and he said that the path reports indicated no tumor, but indolant cancer clusters that didn't need any treatment. He was concerned that my PSA history indicated that I had a large amount of PC somewhere that had yet to be uncovered and put me through several more tests.
A color doppler targeted biopsy in 11-08 found a large tumor in the transition zone, gleason 6 and 7. Because of my high PSA Dr. suspected lymph node involvement, 30% chance, and sent me to Holland for a Combidex MRI, even though bone and CT scans were clear.
Combidex MRI showed clear lymph nodes and a 2,5 cm tumor in the anterior. I was his 1st patient to come up clear on the Combidex which has a 96% accuracy,
I've been on a no meat and dairy diet since 12-08 and PSA reduce to 30 while I awaited the Combidex MRI.
The location of the tumor in the anterior apex next to the urethea makes a good surgical margin very unlikely. Currently on Casodex and Proscar for 8 weeks to shrink my 60 mm prostate. Treatment will be seeds followed by 5 weeks of IMRT while continuing on Casodex and Proscar. So far no side affects from the Casodex.
As of April 10 and 7 weeks on Casodex and Proscar PSA has gone from 30 to 0.62 and protate from 60mm to 32mm. Very minor side affects. Doc says all this indicates tumor is not aggessive
Awaiting schedule for seed impants