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Regular Member

Date Joined Jan 2009
Total Posts : 71
   Posted 5/15/2009 7:08 PM (GMT -6)   
The doctor's assistant at the Cleveland Clinic today told me they never give prostate cancer patients chemo because they don't think it's effective. I'd appreciate any feedback.
Keeping the forum in my prayers,
SO diagnosed 4/15/09 age 47
1/15/09=PSA 10
Dx 4/15/09=Right side= Gleason 4+4=7, 40% involved, 5 out of 6 cores positive, perineural invasion present
Left side+ Gleason 4+4=8, 60% involved, 5 out of 6 cores positive, no perineural invasion present
5/14/09=Robotic surgery at Cleveland Clinic by Dr. Gong
pre-op PSA 15, MRI shows extracapsular penetration

Steve n Dallas
Veteran Member

Date Joined Mar 2008
Total Posts : 4835
   Posted 5/16/2009 4:58 AM (GMT -6)   

Prostate Cancer: Chemotherapy

Chemotherapy is the use of any one or combination of cancer-killing drugs. It is prescribed in cases of recurrent or advanced prostate cancer that has not responded to hormone treatment, but it is not used to treat early stage disease.

Chemotherapy is given in cycles of treatment followed by a recovery period. The entire treatment generally lasts three to six months, depending on the type of chemotherapy medications given.

Continued here:


Age 54   - 5'11"   205lbs
Overall Heath Condition - Good
PSA - July 2007 & Jan 2008 -> 1.3
Biopsy - 03/04/08 -> Gleason 6 
06/25/08 - Da Vinci robotic laparoscopy
Catheter in for five weeks.
Dry after 3 months.
10/03/08 - 1st Quarter PSA -> less then .01
01/16/09 - 2nd Quarter PSA -> less then .01
xx/xx/xx   - 3rd Quater skipped
05/14/09  - 4th Quarter PSA -> less then .01
Surgeon - Keith A. Waguespack, M.D.

New Member

Date Joined Jan 2009
Total Posts : 18
   Posted 5/16/2009 9:24 AM (GMT -6)   
It is my understanding that in the early days chemotherapy wasn't very effective for prostate cancer probably because chemo acts best on fast-growing cells and prostate cancer grows slowly.  Through the years it has  been used at later periods after a patient's cancer no longer responds to hormones.  However, there seems to be a renewed interest in using chemo earlier in the process for high-risk patients likely to recur.  There are currently several clinical trials going on to test this, I believe.  The rationale is that the chemo chemicals used today are much more effective, using it earlier in the process means the men are much healthier than men late in the process so more able to tolerate higher chemo levels,  and the now established success of early chemo in cancers such as breast cancer.  Adding a form of Vitamin D seems to work well and increase the effects (but with some toxicities) of the chemical used most commonly today.  There is now a new form of Vitamin D in studies which they are saying is more effective and much less toxic.   
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