new blood test for cancer

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New Member

Date Joined Jun 2009
Total Posts : 14
   Posted 6/4/2009 8:38 AM (GMT -6)   
details here:


Steve n Dallas
Veteran Member

Date Joined Mar 2008
Total Posts : 4840
   Posted 6/4/2009 8:49 AM (GMT -6)   
The article is from Three Years ago. Wonder if there is anything more recent?
Age 54   - 5'11"   205lbs
Overall Heath Condition - Good
PSA - July 2007 & Jan 2008 -> 1.3
Biopsy - 03/04/08 -> Gleason 6 
06/25/08 - Da Vinci robotic laparoscopy
Catheter in for five weeks.
Dry after 3 months.
10/03/08 - 1st Quarter PSA -> less then .01
01/16/09 - 2nd Quarter PSA -> less then .01
xx/xx/xx   - 3rd Quater skipped
05/14/09  - 4th Quarter PSA -> less then .01
Surgeon - Keith A. Waguespack, M.D.

Veteran Member

Date Joined Apr 2009
Total Posts : 990
   Posted 6/4/2009 9:40 AM (GMT -6)   
A quick search of PubMed did not show anything new in cancer screening. Much of the research seems directed at using tNOX to direct anti-cancer drugs to the right spot.
Age at diagnosis 66, PSA 5.5
Biopsy 12/08 12 cores, 8 positive
Gleason 3 + 4 = 7
CAT scan 1/09 negative, Bone scan 1/09 negative

Robotic surgery 03/03/09 Catheter Removed 03/08/09
Post surgical pathology report. Lymph nodes negative, Seminal vesicles negative
Surgical margins positive, Capsular penetration extensive Gleason 4 + 3 = 7
At 6 weeks: 1 pad/day, 1 pad/night -- mostly dry at night.

Tony Crispino
Veteran Member

Date Joined Dec 2006
Total Posts : 8128
   Posted 6/4/2009 11:39 AM (GMT -6)   
T2-erg and PCA3 are the latest that will be approved this year.  CTC is also available at limited locations.
Below is from ZERO-The Project to End Prostate Cancer.  This was released just a few days ago...
 Age 46 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Geason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 11, 2009): <0.1
My Journal is at Tony's Blog  

New Member

Date Joined Jun 2009
Total Posts : 14
   Posted 6/4/2009 2:13 PM (GMT -6)   
Excerpt from tNOX blood test from that web page (
Sept. 13, 2006 (Chicago) -- Researchers have identified a protein in the blood present only in people with cancer that may help doctors spot cancer early.

The protein, called tNOX, is the first tumor marker for all cancers ever described, says D. James Morre, PhD, distinguished professor of medicinal chemistry at Purdue University in West Lafayette, Ind.

"If tNOX is present, cancer is present," he tells WebMD. "Presumably, the more there is, the worse the disease."
Putting tNOX to the Test

Normal cells have the NOX enzyme only when they are dividing in response to growth hormone signals. In contrast, cancer cells have NOX activity at all times.

This overactive form of NOX, known as tNOX -- for tumor-associated NOX -- has long been thought to be vital for the growth of cancer cells because drugs that inhibit tNOX activity also block tumor cell growth.

In two new studies presented here at a meeting of the American Association for Cancer Research, Morre and colleagues put the protein to the test.

It passed with flying colors, he says.
Diagnosed: age 55, now 58
Diagnosis: Small cell anaplastic androgen-independent adenocarcinoma of the prostate
PSA: 3.15
Gleason: 9 (5+4)
1/06: Radical Retropubic Prostatecomy
9/06-2/07: chemo: first taxotere and then etoposide/cisplatin
5/07: radiation: 55 grey units over 30 days
Cancer in remission 2/07-4/09
Next: surgery (6/9) to deal with cancers return
casodex to follow surgery and then watchful waiting.

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