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Geebra
Regular Member


Date Joined May 2009
Total Posts : 476
   Posted 6/15/2009 10:08 PM (GMT -6)   
Started on Casodex a couple of days ago and will have a Lupron shot in a week. I don't drink a lot, but enjoy a few drings on a weekend. In a booklet for ADT I read that "alcohol may interfere with this treatment". shocked  Called a doc and he said it might interfere with Casodex.
 
Anybody has an opinion/experience with this? I would think it would be a significant hardship for those on long term ADT treatment, enough to be mentioned more prominantly?
 
For now I am dry until further notice. Together with hormonal changes, this can really make me cranky  smilewinkgrin
 

Previous 5 biopsies over 4 years negative

PSA going from 3.8 to 28

Father died from PCa @ 78 - normal PSA and DRE

Dx Nov 2007, age 46

PSA 29, Gleason 4+4=8

Decided to participate in clinical trial at Duke

6 rounds of chemo (Taxotere+Avastin)

1/8/2008

33.90

1/11/2008

29.50

1/31/2008

38.20

2/21/2008

32.00

3/13/2008

26.20

4/3/2008

26.60

4/24/2008

20.60

followed by RRP at Duke (Dr. Moul) on 6/16/2008

Pathology

Gleason downgraded 4+3=7

  Duke: T2c N0MX, one positive margin

  Sloan Kettering: T3a N0MX, extraprostatic extension, two positive margins

PSA undetectable for 8 months, then

2/6/2009

0.10

4/26/2009

0.17

5/22/2009

0.20

6/11/2009

0.27

6 Months ADT started 6/12/2009

IMRT to start mid-Aug


Steve n Dallas
Veteran Member


Date Joined Mar 2008
Total Posts : 4849
   Posted 6/16/2009 7:30 AM (GMT -6)   
If the booklet AND my Doc said cut out the booze - they wouldn't have to tell me twice wink
Age 54   - 5'11"   205lbs
Overall Heath Condition - Good
PSA - July 2007 & Jan 2008 -> 1.3
Biopsy - 03/04/08 -> Gleason 6 
 
06/25/08 - Da Vinci robotic laparoscopy
Catheter in for five weeks.
Dry after 3 months.
 
10/03/08 - 1st Quarter PSA -> less then .01
01/16/09 - 2nd Quarter PSA -> less then .01
xx/xx/xx   - 3rd Quater skipped
05/14/09  - 4th Quarter PSA -> less then .01
Surgeon - Keith A. Waguespack, M.D.
 


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25394
   Posted 6/16/2009 7:30 AM (GMT -6)   
Would be best not to drink at all during the times you are on those meds, but you have to make that choice, you do need them to work at their peak to benefit you, just my personal thought.

I guess you should have asked the doc if smoking pot would be ok instead? Just kidding.
Age 56, 56 at DX, PSA 7/7 5.8, 7/8 12.3,9/8 14.5
3rd Biopsy Sept 08: Positive 7 of 7 cores, 40-90%, Gleason 7, 4+3
Open RP surgery 11/14/8, Right nerves spared, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
Post-surgery Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsular, clear margins, clear lymph nodes 
First PSA Post Surgery   2/9 .05, 5/9 .10 doubled in 3 months, new test in six weeks, then possibly off for salvage radiation
 
 


Geebra
Regular Member


Date Joined May 2009
Total Posts : 476
   Posted 6/16/2009 7:54 AM (GMT -6)   
It is not a huge sacrifice, but an unexpected one. I did not drink while on chemo - wine did not taste right and I am an only occasional drinker of beer.

I dont smoke, so pot would be a poor option, but I did try hash once - it was too strong of an effect for my taste. Maybe you have to get used to it? ;-)

Previous 5 biopsies over 4 years negative

PSA going from 3.8 to 28

Father died from PCa @ 78 - normal PSA and DRE

Dx Nov 2007, age 46

PSA 29, Gleason 4+4=8

Decided to participate in clinical trial at Duke

6 rounds of chemo (Taxotere+Avastin)

1/8/2008

33.90

1/11/2008

29.50

1/31/2008

38.20

2/21/2008

32.00

3/13/2008

26.20

4/3/2008

26.60

4/24/2008

20.60

followed by RRP at Duke (Dr. Moul) on 6/16/2008

Pathology

Gleason downgraded 4+3=7

  Duke: T2c N0MX, one positive margin

  Sloan Kettering: T3a N0MX, extraprostatic extension, two positive margins

PSA undetectable for 8 months, then

2/6/2009

0.10

4/26/2009

0.17

5/22/2009

0.20

6/11/2009

0.27

6 Months ADT started 6/12/2009

IMRT to start mid-Aug


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25394
   Posted 6/16/2009 8:40 AM (GMT -6)   
Geebra, you do realize I was kidding about the pot? lol.
Age 56, 56 at DX, PSA 7/7 5.8, 7/8 12.3,9/8 14.5
3rd Biopsy Sept 08: Positive 7 of 7 cores, 40-90%, Gleason 7, 4+3
Open RP surgery 11/14/8, Right nerves spared, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
Post-surgery Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsular, clear margins, clear lymph nodes 
First PSA Post Surgery   2/9 .05, 5/9 .10 doubled in 3 months, new test in six weeks, then possibly off for salvage radiation
 
 


Geebra
Regular Member


Date Joined May 2009
Total Posts : 476
   Posted 6/16/2009 2:59 PM (GMT -6)   
So was I. ;-)


Gunner59
Regular Member


Date Joined Nov 2008
Total Posts : 110
   Posted 6/16/2009 4:38 PM (GMT -6)   
Does that mean if I ever start hormone therapy, I'll have to give up crack and meth?? smilewinkgrin
Age 48 at diagnosis
3 Jul 08 PSA 27.21
Biopsy positive 3+3=6 on 9 of 24 punches
Bone scan clear
22 Sep 08 Laproscopic Radical Prostatectomy and bilateral pelvic Lymphadenectomy
Gleason 3+4=7 after prostate removal, lymph nodes clear
Stage T2B
PSA at 3 months=undetectable
6 month PSA still 0


Doting Daughter
Veteran Member


Date Joined Aug 2007
Total Posts : 1064
   Posted 6/16/2009 9:27 PM (GMT -6)   
I hope that is not the case. My father has been on Lupron for over a year now and was on Casodex for a short time too. Giving up sex was asking a lot, giving up beer, red meat AND sex would be a deal breaker :) Thankfully, his PSA's have been undetectable on the Lupron and I pray they will remain that way.
Father's Age 62 (now 63)
Original Gleason 3+4=7, Post-Op Gleason- 4+3=7,
DaVinci Surgery Aug 31, 2007
Focally Positive Right Margin, One positive node. T3a N1 M0.
Bone Scan/CT Negative (Sept. 10, 2007)
Oct. 17 PSA 0.07
Nov. 13 PSA 0.05
Casodex adm. Nov 07, Lupron beg. Dec 03, 2007 2 yrs
Radiation March 03-April 22, 2008- 8 weeks 5x a week
July 2, 08 PSA <.02
Oct. 10, 08 PSA <.02
Praying for a cured dad.

Co-Moderator Prostate Cancer Forum


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 6/16/2009 9:45 PM (GMT -6)   
AstraZeneca makes no mention in the dosage publications about alcohol consumption while on Casodex...see below...
 
 
Alcohol consumption while on ADT is no different than not on ADT.  Moderation is what my oncologist said.  I told him I ain't giving up my wine.  He said good but don't over consume it.
 
Tony
 Age 46 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Geason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 11, 2009): <0.1
 
My Journal is at Tony's Blog  
 
STAY POSITIVE!


Geebra
Regular Member


Date Joined May 2009
Total Posts : 476
   Posted 6/17/2009 10:15 AM (GMT -6)   
Interesting. I am going to press the doc and read up on it some more. Thanks, everybody. I do like my wine...

Ohio - was your comment directed at me or Gunner?


Gunner59
Regular Member


Date Joined Nov 2008
Total Posts : 110
   Posted 6/17/2009 4:01 PM (GMT -6)   
Probably at me. My attempt to inject a bit of humor into what can be such a serious subject seems to have fallen flat.
Age 48 at diagnosis
3 Jul 08 PSA 27.21
Biopsy positive 3+3=6 on 9 of 24 punches
Bone scan clear
22 Sep 08 Laproscopic Radical Prostatectomy and bilateral pelvic Lymphadenectomy
Gleason 3+4=7 after prostate removal, lymph nodes clear
Stage T2B
PSA at 3 months=undetectable
6 month PSA still 0

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