Prostate Cancer Infolink article

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SHU93
Regular Member


Date Joined Aug 2008
Total Posts : 328
   Posted 6/16/2009 2:23 PM (GMT -6)   
Read this article today on a study and was thinking, am I overly optimistic to live past 20 more years after my intial treatment of localized pc?? Based on this article saying this is the case?? My ? is if not 20 years what is my expectancy based on treatment, are these publsihed anywhere?
 
First PSA : 4.17 5/2008
Second PSA After 2 weeks of antibiotics : 3.9 6/2008
DRE: Negative 5/2008
Biopsy : 6 out 12 Postive all on right side, Gleason 7 (3+4).
Bone Scan/CAT Scan: Clear 7/2008
Cystoscope: Normal 7/2008
Prostate MRI: Normal 7/2008
Da Vinci Surgery 7/2008
PostOp: T2c (On Both sides), margins clear, seminal clear, nodes, clear. Gleason 6(3+3).
First PostOp PSA 9/2008: <0.01
2nd PSA 12/2008: <0.1 (Different Lab then 1st)
3rd PSA 3/2009: <0.1
 
 


LV-TX
Veteran Member


Date Joined Jul 2008
Total Posts : 966
   Posted 6/16/2009 3:55 PM (GMT -6)   
SHU93...I think the premise was average life expectancy for Males in the US is 75.4 years...that is the average. The study you sited stated that non-disease life expectancy of the cohorts surveyed was 22.9 years...which meant that the average age was around 52. In your case I would expect you to live far longer than the 20 years. Statistics can be fun...but use them with extreme caution when putting yourself into some statistic involving mortality, because you are not a statistic. As you have read, many many men live much longer than the average shown above...with and without prostate cancer.
You are beating back cancer, so hold your head up with dignity
 
Les
 
Age 58 at Diagnosis
Oct 2006 - PSA 2.6 - DRE Normal
May 2008 - PSA 4.6 - DRE Normal / TRUS normal
July 2008 - Biopsy 4 of 12 Positive 5 - 30% Involved Bilateral w/PNI - Gleason (3+3)6 Stage T1C
Robotic Surgery Sept 18, 2008
Pathology October 1, 2008 - Gleason 7 (3+4) Staged pT2c NO MX - Gland 50 cc
Seminal Vesicles and Lymph Nodes clear
Positive Margins Right Posterior Lobe
PSA 5 week Oct 2008 <.05
                   3 month Jan 2009 .06
                   6 month April 2009 .06


CapnLarry
Regular Member


Date Joined Apr 2009
Total Posts : 75
   Posted 6/16/2009 4:46 PM (GMT -6)   
As some of the follow-up comments for the original article point out, this was a small study. Extrapolating from "not much" is dangerous.

In any case, it seems to come down to (a) comorbidities, and (b) metastasis/recurrence. If you don't get recurrence, then your life expectancy is mostly up to your lifestyle/vices and your genes (comorbidities). Sloan-Kettering and U Montreal, among others, have nomograms on the probability of metastasis/recurrence for various fact situations, and Sloan-Kettering has one for general life expectancy without PC given race and current age.

Just bear in mind that the survival numbers in those nomograms that give 10 year expectancy, for example, are based on guys that had surgery at least 10 years ago. Things have gotten better since.

However, the "1 percent in 15 years" figure is one that I can't cross-foot with anything I know from other sources. Maybe 15 percent in 15 years, given the Gleason 6-7 number that the article quotes.
Larry Shick
Personal homepage incl. PCa story: www.sv-moira.com.
01/09: Diagnosed (age 60) biopsy PSA 4.4, free PSA 9%, T2c stage, Gleason 7 (3+4), 7 of 14 cores; 6'2", 200 lbs.
03/09: Robotic surgery (Dr. Kawachi, City of Hope) 47 gms, 10% involved, staging/Gleason unchanged (pT2cNXMX), margins clear, no ECE/sem ves involvement, fully continent from day 1, some success w/Viagra 50mg/day.
Followup: 05/09 0.006


engineer55
Regular Member


Date Joined May 2009
Total Posts : 121
   Posted 6/16/2009 4:56 PM (GMT -6)   
I really don't get the point of the article. Men who expect to live longer get more surgery, isn't that obvious.

The other thing is with the demise of smoking and the force feeding of lipitor I would expect life avgs to climb rapidly the next few decades. I really don't think 75 will be the norm 20 years from now.

Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 6/16/2009 6:26 PM (GMT -6)   
Hi SHU,
As usual, my friend, Mike Scott puts together another great blog entry. Depending on who you are, life expectancy ycan be more defined in your bloodlines. But the stats in this article reflect what you will see posted soon by major advocacy groups. No surprise, Mike is a board member or founder of many of them.

Thanks for the post, SHU.

Tony
 Age 46 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Geason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 11, 2009): <0.1
 
My Journal is at Tony's Blog  
 
STAY POSITIVE!


geezer99
Veteran Member


Date Joined Apr 2009
Total Posts : 990
   Posted 6/17/2009 7:17 AM (GMT -6)   
Here is a link to the full article


www.jabfm.org/cgi/content/full/22/3/247?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=expectations&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT

Essentially it says that newly diagnosed PC patients think that they will die sooner if not treated and live longer if treated than the actual statistical data shows.

Well, the theme of this board is pretty much learn about your disease and learn about your options. So this study shows why we exist.
Age at diagnosis 66, PSA 5.5
Biopsy 12/08 12 cores, 8 positive
Gleason 3 + 4 = 7
CAT scan 1/09 negative, Bone scan 1/09 negative

Robotic surgery 03/03/09 Catheter Removed 03/08/09
Post surgical pathology report. Lymph nodes negative, Seminal vesicles negative
Surgical margins positive, Capsular penetration extensive Gleason 4 + 3 = 7
At 6 weeks: 1 pad/day, 1 pad/night -- mostly dry at night.

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