1st Post-surgery PSA

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Regular Member

Date Joined Jan 2009
Total Posts : 71
   Posted 7/10/2009 8:33 PM (GMT -6)   
Surgery was 7 weeks ago and his PSA was .11. How bad/good is that? The two people we've seen now both recommended hormone treatment with the radiation. He thinks his PSA is low enough that it's okay to do radiation first and then see if it rises before doing hormone treatment. I'd appreciate any thoughts.
Prayers to all,

SO diagnosed 4/15/09 age 47
1/15/09=PSA 10
Dx 4/15/09=Right side= Gleason 4+4=7, 40% involved, 5 out of 6 cores positive, perineural invasion present
Left side+ Gleason 4+4=8, 60% involved, 5 out of 6 cores positive, no perineural invasion present
5/14/09=Robotic surgery at Cleveland Clinic by Dr. Gong
pre-op PSA 15, MRI shows extracapsular penetration
Pathology 5/21/09-T3a, N1MX, positive margins, 1 out of 13 lymph nodes positive, left nerves spared

Ed C. (Old67)
Veteran Member

Date Joined Jan 2009
Total Posts : 2461
   Posted 7/10/2009 9:46 PM (GMT -6)   
DanaA, From the little that I know and what I've read here and elsewhere, the best approach is to do both. Radiation will only work if everything is local. At this point, you don't know if it local or systemic. ADT with radiation seems to be the normal salvage treatment after surgery.
Age: 67 at Dx on 12/30/08
PSA 9/05 1.15; 8/06 1.45; 12/07 2.41; 8/08 3.9; 11/08 3.5 free PSA 11%
2 cores out of 12 were positive Gleason (4+4) and (4+5)
Negative CT scan and bone scan done on 1/16
Robotic surgery performed 2/9/09 Dr Fagin, Austin TX
Pathology report:
Prostate weighed 57 grams size:5.2 x 5.0 x 4.9 cm
Bilateral 10-20% involved
Gleason 4+4
both nerve bundles removed,
pT3a Nx Mx, Negative margins
seminal vesicles clean, lymph nodes: not dissected
continent after 4 months
1st PSA test 4/7/09 result <0.1

Veteran Member

Date Joined Aug 2007
Total Posts : 1015
   Posted 7/10/2009 9:49 PM (GMT -6)   
Hi DanaA,

I'm sorry about the news. I don't know much about this topic since I chose surgery. However, I've read that hormone therapy prior to radiation has been shown in studies to enhance the killing effect of the radiation on any remaining prostate tissue.

I'm sure others with more knowledge will chime in.

I wish you and your S.O. the very best.

Da Vinci LRP July 31, 2007… 54 on surgery day
PSA 4.3 Gleason 3+3=6 T2a Confined to Prostate
6th PSA 06/09 still less than 0.1

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