Just read a paper by Strum, Tisman and Scholz on PIN. HGPIN is more predictive in older people with a psa greater than 4. PIN appears to predate the appearance of PC by more than 5 years.
1. Monitor PSA and get a DRE minimum every 6 months.
2. Repeat biopsies at least every 12 months.
3. Patients with High Grade PIN should be considered as having occult PC until proven otherwise.
If supplements like pomegranites are good for those that have PC and are proven to slow the growth of PC I would imagine that they would have the same affect on HGPIN. Be sure that you have a good doctor that is experienced in AS and PC diagonostics.
You may want to Google HGPIN; a couple of months ago I ran across an article about
a research center that specializes in HGPIN using some natural formulation that eliminates it.
64 years old.
PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DX BPH and continue to get biopsies yearly. Positive Biopsy in 10-08, 2 cores of 25, G6 less than 5%. Scheduled Surgery as recommended.
2nd Opinion from Dr Sholtz, an Oncologist said DX wrong, path shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G 4+3 approx 2.5cm diameter.
Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy.
Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and burining urination. Daily activities resumed day after implants.
Scheduled for 5 weeks IMRT in July