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maldugs
Veteran Member


Date Joined Jun 2007
Total Posts : 784
   Posted 8/10/2009 12:52 AM (GMT -6)   
Hi, met with Oncologist this morning to discuss the rise in my PSA, he thinks that the Pca cells that are generating the antigen escaped the prostate before the operation, and as the radiation treatment has not resulted in a lowering of the PSA after 1 year, and the fact that my immediate post op PSA was .0.5, that the microscopic cells that are somwhere else in my body, ie systematic.

He also said that there was no way of detecting where the cells were, until I develop symptoms or have a dramatic rise or doubling time in the PSA, so that is where I am at right now.

I am to see him again in Sept 2010, and my Urologist in January 2010 with a new PSA test, they also want me to have a colonoscopy due to the bowel probs I have had since the radiation....wot next!!

All the best from Mal.
age 67 PSA 5.8 DRE slightly firm Rt
Biopsy 2nd July 07 5 out of 12 positive
Gleason 3+4=7 right side tumour adenocarcinoma stage T2a
RP on 30th July,

Post op Pathology, tumour stage T3a 4+3=7, microcsopic evidence of capsular penetration, seminal vessels, bladder neck,are free of tumour, lymph nodes clear, no evidence of metastatic malignancy, tumour does not extend to the apical margins.

Post op PSA 0.5 26th Sept.
PSA 23rd Oct.0.5 seeing Radiation Onocologist 31st Oct.
Started radiation treatment on 5th Dec, to continue until 24 Jan. 08.
Finished treatment, next PSA on 30th April.
PSA 30th April 0.4
PSA 30th July 0.5
PSA 27th Oct 0.4 (I am now 68)
PSA 11th March 09 0.5
PSA 3rd Augiust 09 0.6


Doting Daughter
Veteran Member


Date Joined Aug 2007
Total Posts : 1064
   Posted 8/10/2009 8:39 AM (GMT -6)   
Good luck with the colonoscopy and please keep us posted! Thinking of you!
Father's Age DX 62 (now 64)
Original Gleason 3+4=7, Post-Op Gleason- 4+3=7,
DaVinci Surgery Aug 31, 2007
Focally Positive Right Margin, One positive node. T3a N1 M0.
Bone Scan/CT Negative (Sept. 10, 2007)
Oct. 17 PSA 0.07
Nov. 13 PSA 0.05
Casodex adm. Nov 07, Lupron beg. Dec 03, 2007 2 yrs
Radiation March 03-April 22, 2008- 8 weeks 5x a week
July 2, 08 PSA <.02
Oct. 10, 08 PSA <.02
Praying for a cured dad.

Co-Moderator Prostate Cancer Forum


James C.
Veteran Member


Date Joined Aug 2007
Total Posts : 4462
   Posted 8/10/2009 8:45 AM (GMT -6)   
Mal, thanks for the the update. Hope you get good results from the test.
James C. Age 62
Co-Moderator- Prostate Cancer Forum
4/07 PSA 7.6, referred to Urologist, recheck 6.7
7/07 Biopsy: 3 of 16 PCa, 5% involved, left lobe, GS 3/3=6
9/07 Nerve sparing open RRP 110gms.- Path Report: GS 3+3=6 Stg. pT2c, 110gms, margins clear
22 mts: ED- 50 mg Viagra 3X week, pump daily,Trimix 30/1/20-.10ml 2X week continues
PSA's: .04 each test since surgery


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 8/10/2009 9:11 AM (GMT -6)   
Mal,
We are watching closely...I love ya buddy, and I am not too happy with that visit to the Oncologist. But I do know that this disease can be really super slow and there is indeed plenty left to do. Did the oncologist mention a timeline to begin Hormone therapy? The colonoscopy will give you some insite as to whether there was any scarring after the radiation.

Keep your family close, and we will do the same with you. Prayers for peace and good results are headed your way,

Tony
 Age 47 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Geason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 11, 2009): <0.1
 
My Journal is at Tony's Blog  
 
STAY POSITIVE!


maldugs
Veteran Member


Date Joined Jun 2007
Total Posts : 784
   Posted 8/10/2009 6:08 PM (GMT -6)   
Hi, Thanks to you all for the replies and wishes, Tony, the oncologist said they will take hormonal action when the PSA reaches 2. or I get a quick doubling time, but he did say that wherever the cells are they are growing very very slowly,and there are many treatment options. Was in a bit of fuzz when I posted yesterday, not thinking very well.

love to you all. Mal.
age 67 PSA 5.8 DRE slightly firm Rt
Biopsy 2nd July 07 5 out of 12 positive
Gleason 3+4=7 right side tumour adenocarcinoma stage T2a
RP on 30th July,

Post op Pathology, tumour stage T3a 4+3=7, microcsopic evidence of capsular penetration, seminal vessels, bladder neck,are free of tumour, lymph nodes clear, no evidence of metastatic malignancy, tumour does not extend to the apical margins.

Post op PSA 0.5 26th Sept.
PSA 23rd Oct.0.5 seeing Radiation Onocologist 31st Oct.
Started radiation treatment on 5th Dec, to continue until 24 Jan. 08.
Finished treatment, next PSA on 30th April.
PSA 30th April 0.4
PSA 30th July 0.5
PSA 27th Oct 0.4 (I am now 68)
PSA 11th March 09 0.5
PSA 3rd Augiust 09 0.6


IdahoSurvivor
Veteran Member


Date Joined Aug 2007
Total Posts : 1015
   Posted 8/10/2009 10:44 PM (GMT -6)   
Hey Mal,

I'm glad the doctors don't think quick action is needed. You PSAs haven't moved much since post surgery.

Like Tony and the docs say, you have many options available to you. I wish you well, my friend.

Take good care and lean on your friends on this forum.

Kind regards,

Idaho (Barry)
Da Vinci LRP July 31, 2007… 54 on surgery day
PSA 4.3 Gleason 3+3=6 T2a Confined to Prostate
6th PSA 06/09 still less than 0.1


BillyMac
Veteran Member


Date Joined Feb 2008
Total Posts : 1858
   Posted 8/11/2009 3:49 AM (GMT -6)   
Hey Mal,
How you going? The PSA increase seems to be particularly slow. If the labs figures are correct it would indicate at least a 2 year doubling time..........probably better to call it a slow creep. Then again perhaps it's lab variation..........I see from your figures it gone down as well as up. I sure don't envy you that colonoscopy............that preparation-----yuk. Best wishes on both fronts,
Bill
1/05 PSA----2.9 3/06-----3.2 3/07-------4.1 5/07------3.9 All negative DREs
Aged 59 when diagnosed
Biopsy 6/07
4 of 10 cores positive for Adenocarcinoma-------bummer!
Core 1 <5%, core 2----50%, core 3----60%, core 4----50%
Biopsy Pathologist's comment:
Gleason 4+3=7 (80% grade 4) Stage T2c
Neither extracapsular nor perineural invasion is identified
CT scan and Bone scan show no evidence of metastases
Da Vinci RP Aug 10th 2007
Post-op pathology:
Positive for perineural invasion and 1 small focal extension
Negative at surgical margins, negative node and negative vesicle involvement
Some 4+4=8 identified ........upgraded to Gleason 8
PSA Oct 07 <0.1 undetectable
PSA Jan 08 <0.1 undetectable
PSA April 08 <0.001 undetectable (disregarded due to lab "misreporting")
PSA August 08 <0.001 undetectable (disregarded due to lab "misreporting")
Post-op pathology rechecked by new lab:
Gleason downgraded to 4+3=7
Focal extension comprised of grade 3 cells
PSA September 08 <0.01 (new lab)
PSA February 09 <0.01

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