rising psa after surgery

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cave88
Regular Member


Date Joined Jul 2008
Total Posts : 76
   Posted 8/23/2009 7:59 AM (GMT -6)   
Here is a follow-up to my rising psa.
  After my psa rose to 01.3 the surgeon suggested I meet with a radiologist who specializes in prostate cancer.  I met with the radiologist in June.  He suggested I wait until I have another psa test before making a decision.  I agreed and decided to wait.  Last weeks result was a jump from 0.13 to 0.2.  Based on previous tests this quite a large jump.  Back in May, Sterd82 suggested that 0.2 was a good line to draw in the sand.  This is the number I had in my mind when it was time to take further action.  Now I am here.
  I meet with the oncology surgeon tomorrow.  I will discuss with him radiation and HT.  Then I will talk with the radiologist. Does anyone have more ideas?  Our GP has suggested to my wife that maybe I should wait.  He suggested there might be disadvantages to radiation over waiting.
  I was eating healthier after surgery.  Started drinking pomengranite juice, hardly any cheese and other fats.  I went from eating cheeseburgers three times a week to maybe once every other month.  In the last three months I kind of went back to my old eating habits.  Cheeseburgers once a week not three though. I also quit the pomegranite juice.  I couldn't find the juice I was drinking.  Anyway, would this be reason for such a large jump in my psa from 0.13 to 0.20?  It was only rising 0.01 every three months prior to this.
 
Thank you
 
age:  46
1st psa Apr 08 3.06
2nd psa 6/16/8 4.02,  DRE showed nothing abnormal
biopsy 7/10/08 positive 5 of 12
Da Vinci 8/04/8 Parkview Memorial in FT Wayne IN 
gleason 3 + 3 = 6
prostate 27 g, 4 x 4 x 3.1 cm
Stage:  pT2cNXMX
margins:  apical margin involved
no extraprostatic extension of tumor
seminal vesicle involvement: absent
3 month psa  0.11, 11/08
6 month psa 0.12,  2/09/0
9 month psa 0.13, 5/01/09
1 year psa 0.20, 8/17/2009
 
 
 


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 8/23/2009 8:47 AM (GMT -6)   
cave, sorry you are dealing with a post surgery rising psa. i am in the same boat as you. there would be no way to prove that you eating some "fun" food after trying to eat right has anything to do with your rising numbers. if you have reaccurance, it is because there were cancer cells left behind, and prostate cancer cells produce these minute amounts of PSA, plan and simple. So please don't feel guilty that you are causing this increase.

every radiation oncoologist seems to have a different opinion of when to draw the line in the sand. I have talked to two now in recent times, from the same practice, and they use .50 as the highest effective limit to start salvage radiation treatments. In my personal research, I have read as low as .10, to as high as 2.0. Another group would average out to no higher than 1.0 no matter what.

i am wrestling with the same situation, with post surgery psa's of .05, .10. .11. and now .16. It sure isn't going down, but it still microscopic ammounts of psa. we should compare notes with what we learn.

david in SC
 Age 57, 56 at DX, PSA 7/7 5.8, 7/8 12.3,9/8 14.5
3rd Biopsy Sept 08: Positive 7 of 7 cores, 40-90%, Gleason 7, 4+3
Open RP surgery 11/14/8, Right nerves spared, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
 Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsule, one post. margin, clear lymph nodes 
2009 PSA   2/9 .05, 5/9 .10, 6/9 .11, 8/9 .16
Lastest 7/13 met with Rad. Oncl, considering options, 7/20 Catheter #6 after complete blockage, 8/14 met with Rad Oncl, still talking option, 8/18 - had laser scope surgery to clear blockage, now on Catheter #7
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 


Jakester
Regular Member


Date Joined Aug 2009
Total Posts : 285
   Posted 8/23/2009 1:23 PM (GMT -6)   
Hi, I've just joined although I've benefited from the conversations over the last couple months after finding this site. I don't have a lot to contribute except to say that I'm also in the same boat. My 6 week, 3 month and six month post LRP psa tests were .1 and my 9 month taken this month 8/09 was .2 . My urologist/surgeon said he was "worried" and in two months wanted another psa and a bone scan (I've never had one). And if the psa does not return to .1 then he will have me consult with a radiation guy. He did reiterate, as he had with my previous psa results, that there is a possibility that benign prostate tissue at the bladder neck when he peeled the prostate off ant that could be causing the psa. My GP (I had my annual physical a few days ago) said not to worry because "it is just 1 observation" and I should just cool my jets for a couple months. I've also joined the Yana website. Terry Herbert wondered if the psa rise could be linked to the fact that I broke all my ankle bones two months ago. I believe Terry's point was that psa results at this level can be influenced by other factors. We are all different I guess but I'm thinking I'll wait the two months and try not to think about it (easy to say).
Diagnosed 8/2008 Pre-op psa 4.2
7 of 12 biopsies postitive 3+3
DaVinci LRP 11/08
Post Op pathology clear margins, confined to prostate, absent extraprostatic extension, vascular or perineural. Gleason 3+4=7, 5-10% of 4 and location in right mid-gland.
3 month psa .1 2/09, 6 month .1 5/09, 9 month .2 8/09


livinadream
Veteran Member


Date Joined Apr 2008
Total Posts : 1382
   Posted 8/23/2009 3:10 PM (GMT -6)   
Great thread. Cave it sounds like you are dealing with rising psa and I am glad you are taking it serious and looking at evasive action. Jakester welcome to HW sure are glad to have you. I am sorry to see that you to are dealing with rising psa. I think for both of you guys that there are plenty of successful treatment models on the table so stay positive and lets get this think under control. Our goal here at HW is that we all grow old together and as we die out at 100 years old the others can gather and preach our eulogies. By the way we like having fun to.
Love you all

dale
My PSA at diagnosis was 16.3
age 47 (current)

http://www.caringbridge.org/visit/dalechildress

My gleason score from prostate was 4+5=9 and from the lymph nodes (3 positive) was 4+4=8
I had 44 IMRT's
Casodex
Currently on Lupron
I go to The Cancer Treatment Center of America
Married with two kids
latest PSA 5-27-08 0.11

PSA July 24th, 2008 is 0.04
PSA Dec 16th, 2008 is .016
PSA Mar 30th, 2009 is .02
PSA July 28th 2009 is .01

Testosterone keeps rising, the current number is 156, up from 57 in May

T level dropped to 37 Mar 30th, 2009
cancer in 4 of 6 cores
92%
80%
37%
28%


cave88
Regular Member


Date Joined Jul 2008
Total Posts : 76
   Posted 8/23/2009 8:50 PM (GMT -6)   
Purg,

We do seem to be travelling down a very similar path. I will keep you informed. I am pretty sure I will opt for treatment asap instead of more waiting. I will see what options for further treatment are available. It is great to read here what others are doing.
With the diet thing. I was just thinking that the diet could have an influence on psa results and the growth of cancer. Not sure just speculation. I know there are others out here who are convinced that diet can influence the growth of pca. The junk bond guy, Mike Milken,
has pca and he supposedly is controlling its spread by eating fruits and vegetables. I am going to go back to my healthier eating ways no matter what influence if any it has on pca. After all of this pca stuff, I would feel rather foolish having a heart attack because of a poor diet.

Jon
age:  46
1st psa Apr 08 3.06
2nd psa 6/16/8 4.02,  DRE showed nothing abnormal
biopsy 7/10/08 positive 5 of 12
Da Vinci 8/04/8 Parkview Memorial in FT Wayne IN 
gleason 3 + 3 = 6
prostate 27 g, 4 x 4 x 3.1 cm
Stage:  pT2cNXMX
margins:  apical margin involved
no extraprostatic extension of tumor
seminal vesicle involvement: absent
3 month psa  0.11, 11/08
6 month psa 0.12,  2/09/0
9 month psa 0.13, 5/01/09
1 year psa 0.20, 8/17/2009
 
 
 


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 8/23/2009 8:55 PM (GMT -6)   
Jon, I agree, I would never try to talk anyone, male or female, out of a healthy diet. In our lives, we have all kinds of other health issues to deal with other than our bouts of PC. I don't intend to wait forever either, I am wanting a second opinion now with a different radiation treatment center near me before I plan a date with radiation. Plus, I am still recovering from my lastest corrective surgery due to still another stricture in the bladder neck. Definitely needs to be mended properly before attempting radiation for 7 weeks.

Best to you brother.

David in SC
 Age 57, 56 at DX, PSA 7/7 5.8, 7/8 12.3,9/8 14.5
3rd Biopsy Sept 08: Positive 7 of 7 cores, 40-90%, Gleason 7, 4+3
Open RP surgery 11/14/8, Right nerves spared, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
 Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsule, one post. margin, clear lymph nodes 
2009 PSA   2/9 .05, 5/9 .10, 6/9 .11, 8/9 .16
Lastest 7/13 met with Rad. Oncl, considering options, 7/20 Catheter #6 after complete blockage, 8/14 met with Rad Oncl, still talking option, 8/18 - had laser scope surgery to clear blockage, now on Catheter #7
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 8/23/2009 10:14 PM (GMT -6)   
Hi Cave,
Here is a cookbook approved by Mike Milken...I believe you were looking into his diet...
 
Tony
 Age 47 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Geason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 11, 2009): <0.1
 
My Journal is at Tony's Blog  
 
STAY POSITIVE!


Geebra
Regular Member


Date Joined May 2009
Total Posts : 476
   Posted 8/24/2009 7:35 AM (GMT -6)   
Jon, I am too in a similar situation. I am starting radiation today. You can see from my signature that my PSA also jumped rather quickly. It takes few weeks to prep for radiation, so I suggest not waiting too long. You, like me, had positive margins which makes it probable that you have a local recurrence. I decided to go for HT plus pelvic radiation (to kill anything in the limph nodes area). With that treatment, I am on Lupron for two months already (prior to radiation), then two months during and two months after. Good luck!

Father died from poorly differentiated PCa @ 78 - normal PSA and DRE

5 biopsies over 4 years negative while PSA going from 3.8 to 28

Dx Nov 2007, age 46, PSA 29, Gleason 4+4=8

Decided to participate in clinical trial at Duke - 6 rounds of chemo (Taxotere+Avastin)

PSA prior to treatment on 1/8/2008 is 33.90, bounced on 1/31/2008 to 38.20, and down at the end of the treatment (4/24/2008) to 20.60

RRP at Duke (Dr. Moul) on 6/16/2008, Gleason downgraded 4+3=7, T3a N0MX, focal extraprostatic extension, two small positive margins

PSA undetectable for 8 months, then 2/6/2009-0.10, 4/26/2009-0.17, 5/22/2009-0.20, 6/11/2009-0.27

Salvage IMRT + 6 Months ADT: Casodex started 6/12/2009, Lupron 6/22/2009, PSA 6/25/2009-0.1, T=516, 7/23/2009-<0.05, T<10, IMRT to start mid-Aug


Galileo
Veteran Member


Date Joined Nov 2008
Total Posts : 697
   Posted 8/24/2009 7:56 AM (GMT -6)   
You don't want to wait too long if you're going to have salvage radiation.
Stephenson, Kattan, et al, have shown that the pre-salvage PSA reading is a very important variable. You're best off starting before 0.5 if possible (very good results for men who were able to do that) and the next cut point is 1.0 ng/ml.

Original article from Journal of Clinical Oncology ("Predicting the Outcome of Salvage Radiation Therapy for Recurrent Prostate Cancer After Radical Prostatectomy") is here, in full text for free: http://jco.ascopubs.org/cgi/content/full/25/15/2035

Updated nomogram from the article is here: http://jco.ascopubs.org/content/vol25/issue26/images/large/zlj0150759390003.jpeg

This article and nomogram are the basis for the salvage radiation nomogram on the Memorial Sloan Kettering website, http://nomograms.org

G.
Galileo

Dx Feb 2006, PSA 9 @age 43
RRP Apr 2006 - Gleason 3+4, T2c, NX MX, pos margins
PSA 5/06 <0.1, 8/06 0.2, 12/06 0.6, 1/07 0.7.
Salvage radiation (IMRT) total dose 70.2 Gy, Jan-Mar 2007@ age 44
PSA 6/07 0.1, 9/07 and thereafter <0.1
http://pcabefore50.blogspot.com


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 8/24/2009 9:52 AM (GMT -6)   
G,

Your stats in your posted mirror what the radiation oncologisit I met with last week said, same cut off points, he said the .5 was important. At 1.0, he said you lose at least 50% of the effectiveness.

david in sc
 Age 57, 56 at DX, PSA 7/7 5.8, 7/8 12.3,9/8 14.5
3rd Biopsy Sept 08: Positive 7 of 7 cores, 40-90%, Gleason 7, 4+3
Open RP surgery 11/14/8, Right nerves spared, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
 Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsule, one post. margin, clear lymph nodes 
2009 PSA   2/9 .05, 5/9 .10, 6/9 .11, 8/9 .16
Lastest 7/13 met with Rad. Oncl, considering options, 7/20 Catheter #6 after complete blockage, 8/14 met with Rad Oncl, still talking option, 8/18 - had laser scope surgery to clear blockage, now on Catheter #7
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 


Pelahatchie
Regular Member


Date Joined Jul 2007
Total Posts : 86
   Posted 8/24/2009 1:09 PM (GMT -6)   
The conclusion I came to is "The trend is not your friend"  so why wait when there is mounting evidence that the lower the psa when you start the better your chances.  Just my opinion.
Age 45 at DX
 
DX 8/05 Gleason 5, Mayo clinic Second Opinion Gleason 6, PSA 2.8
 
Da Vinci surgery Dr. Dasari, Centennial Nashville 9/24/05
 
Pathology Report Gleason 6, 15 % on left side only very near to the edge of capsule, too close to call on margins, doc's said to watch it very closely, final decision T2A
 
PSA's have basically ranged from <.04 to .05 for two years.
 
no E.D. and no Incontinence, feel very blessed
 
PSA Nov 07 = .06
 
PSA Dec 10th 07 =.07
 
PSA Jan 4th 2008= .1
 
Started Guided IMRT on January 7th, 2008 to treat prostate bed and lymph nodes, completed on March 6th, 2008
 
PSA April 18th 2008 =.03
 
PSA August 18th 2008 = .01 or less, test only goes down to .01
 
PSA August 21st 2009 = .01 or less
 


dsmc
Regular Member


Date Joined Jul 2008
Total Posts : 149
   Posted 8/24/2009 2:31 PM (GMT -6)   
Hi cave,
I had a recurrence @ the 3 yr. mark. I had no positive margins and seemed to have everything going my way and then the trend started. My Doc deemed it a recurrence when I had 3 consecutive rises and it reached .1. I wanted to blast it when it reached the .1 mark and my Uro Doc and Radiation Doc agreed. From the looks of things I had a direct hit as my first psa came in at <0.04. I have a 6 month follow up with the Rad Doc this Thursday and another psa draw in Nov. My opinion would be to getRdone. I wish you all the luck in the world and am sorry you have to even contemplate this problem!

David
Age 54
Pre-op PSA 4.3
Surgery Feb. 17 2005
Post-op Path : Gleason 3+3=6
Right pelvic lymph nodes: negative for metastatic carcinoma
Left pelvic lymph nodes: negative for metastatic carcinoma
extent: right lobe 40% left lobe 10%
capsular penetration: Absent
Seminal vesicles and vasa differentia: Uninvolved
Prostate: 26 grams
Post-op PSA's <0.04 for 3 years
Feb. 08: 0.07, March 08: 0.08, June 08: 0.09 and Sept. 08: 0.1
IGRT scheduled.....November 17th....
FINISHED 01/14/09 YEA!
05/14/09
1st PSA after Salvage RT <0.04..... Another YEA!


norskie
Regular Member


Date Joined Jan 2007
Total Posts : 376
   Posted 8/24/2009 3:50 PM (GMT -6)   
Cave

As you will see from my stats below I have went down pretty much the same path as you after surgery. All looked well until 9 months after when it jumped to .2 then to .3 a couple months later. At this point we were in discussions with the Radiation group and getting all the planning in place to start radation. It was felt because I had a margin that was real close but nothing else involved that it probably was a local reaccurance or a stray cell or two that was missed that this would knock it out. My first rise in PSA was in November of 2007 to .2 by the end of January of 08 it was .3 and when I went in March it was at .42. We started radiation in April finishing in June of 08 and 6 weeks later it not only had went done but fell all the way to .09 which was under the guidelines of detectable at .1. A few weeks later in had fell to <.06 which is a low as they can read and it was that was this past March as well. I have not been checked since but will have a PSA again in November and hopefully all is still down. They felt the way it dropped so fast it was a local reaccurancae and they must have hit it.

I know there is no way to know for sure but I am hopeful this is the case and it's stays <.06 from now on. Good luck to you with this potential next phase and you can have as good of results as I have had at least up to now.

Norskie
norskie
Current age 50, Age at Dx-48 PSA 6.22 on 9-26-06
Biopsy 11-01-06, 2 of 13 cores 10% cancer, 2 other cores abnormal Up-dated 20% prostate cancerous
Gleason score 3+3=6 After Surgery Pathology report 4+3=7 a couple agressive Grade 5 cells found
Da Vinci surgery 01-09-07 UW Madison
Pathology Report- cancer 100 % capsual contained 1-18-07
1st & 2nd Post PSA Blood Test .1 and less - Undetectable
3nd Post PSA Blood Test 01-17-07 .3
March 27th PSA .422 Begin Salvage Radiation April, 14 2008
Radiation Complete June 4, 2008 36 treatments
August 5, 2008 PSA .09 or < .1 again
October 9, 2008 PSA <.06 or as low as my clinic can read.
March 17, 2009 PSA <.06 still as low as my clinic can read.
Incontenence-Pad free since end of May 07 4 1/2 months post surgery 
ED back to 95% prior to surgery - no medication required.


IdahoSurvivor
Veteran Member


Date Joined Aug 2007
Total Posts : 1015
   Posted 8/24/2009 8:36 PM (GMT -6)   
Hi Cave,

After nearly two years of zeros, my PSA was up to 0.06 in June 2009.

Unlike others, I had no detectable positive margins in the post-surgery pathology. Thus, my surgeon believes that there was some benign prostate tissue left behind. She said not to worry and to do another PSA test in 6 months (December). However, I opted for a test in three months in mid-September because I'd like to know where I stand.

My surgeon said that she starts being concerned when post-surgery PSA level reaches 0.1 and it sounded like she'd want me to consider doing something if I reach that milestone.

I wish you the best in your treatment and hope for your success!

Barry
Da Vinci LRP July 31, 2007… 54 on surgery day
PSA 4.3 Gleason 3+3=6 T2a Confined to Prostate
6th PSA 06/09 still less than 0.1


cave88
Regular Member


Date Joined Jul 2008
Total Posts : 76
   Posted 8/24/2009 10:33 PM (GMT -6)   
Wow!!!
Everyone thank you. My decison is to go forward with the radiation treatment. It seems as though there are many who have and will travel down this same path. I will try to stay more in touch with HW. I'm not much of an advice giver but if anyone one can learn from what I am going thru or doing I hope it helps.

Jon
age:  46
1st psa Apr 08 3.06
2nd psa 6/16/8 4.02,  DRE showed nothing abnormal
biopsy 7/10/08 positive 5 of 12
Da Vinci 8/04/8 Parkview Memorial in FT Wayne IN 
gleason 3 + 3 = 6
prostate 27 g, 4 x 4 x 3.1 cm
Stage:  pT2cNXMX
margins:  apical margin involved
no extraprostatic extension of tumor
seminal vesicle involvement: absent
3 month psa  0.11, 11/08
6 month psa 0.12,  2/09/0
9 month psa 0.13, 5/01/09
1 year psa 0.20, 8/17/2009
 
 
 


cave88
Regular Member


Date Joined Jul 2008
Total Posts : 76
   Posted 8/24/2009 10:43 PM (GMT -6)   
TC
Thanks for the cookbook link. Diet seems to help some but not others. There seems to be so many reason why we get pca. There seems to be so many different cures for pca.
age:  46
1st psa Apr 08 3.06
2nd psa 6/16/8 4.02,  DRE showed nothing abnormal
biopsy 7/10/08 positive 5 of 12
Da Vinci 8/04/8 Parkview Memorial in FT Wayne IN 
gleason 3 + 3 = 6
prostate 27 g, 4 x 4 x 3.1 cm
Stage:  pT2cNXMX
margins:  apical margin involved
no extraprostatic extension of tumor
seminal vesicle involvement: absent
3 month psa  0.11, 11/08
6 month psa 0.12,  2/09/0
9 month psa 0.13, 5/01/09
1 year psa 0.20, 8/17/2009
 
 
 


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 8/25/2009 12:34 AM (GMT -6)   
Cave,
I always say that why we get cancer is not as important as what we do about it. Looking back with regret is not a good way to keep a positive mindset. Instead moving forward with today works best for me.

And moving forward, may peace be with you, And hopefully some good recipes too...

Tony
 Age 47 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Geason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 11, 2009): <0.1
 
My Journal is at Tony's Blog  
 
STAY POSITIVE!


cave88
Regular Member


Date Joined Jul 2008
Total Posts : 76
   Posted 8/30/2009 3:56 PM (GMT -6)   
All,

Met with radiologist. I have decided to start radiation in about 2 weeks. IG-EBRT. It will be done in Ft Wayne Indiana. 39 sessions over 8 weeks.
age:  46
1st psa Apr 08 3.06
2nd psa 6/16/8 4.02,  DRE showed nothing abnormal
biopsy 7/10/08 positive 5 of 12
Da Vinci 8/04/8 Parkview Memorial in FT Wayne IN 
gleason 3 + 3 = 6
prostate 27 g, 4 x 4 x 3.1 cm
Stage:  pT2cNXMX
margins:  apical margin involved
no extraprostatic extension of tumor
seminal vesicle involvement: absent
3 month psa  0.11, 11/08
6 month psa 0.12,  2/09/0
9 month psa 0.13, 5/01/09
1 year psa 0.20, 8/17/2009
 
 
 


Geebra
Regular Member


Date Joined May 2009
Total Posts : 476
   Posted 8/30/2009 4:00 PM (GMT -6)   
Good luck. I am four sessions in. So far so good. It is quick, painless and so far no side effects.

Father died from poorly differentiated PCa @ 78 - normal PSA and DRE

5 biopsies over 4 years negative while PSA going from 3.8 to 28

Dx Nov 2007, age 46, PSA 29, Gleason 4+4=8

Decided to participate in clinical trial at Duke - 6 rounds of chemo (Taxotere+Avastin)

PSA prior to treatment on 1/8/2008 is 33.90, bounced on 1/31/2008 to 38.20, and down at the end of the treatment (4/24/2008) to 20.60

RRP at Duke (Dr. Moul) on 6/16/2008, Gleason downgraded 4+3=7, T3a N0MX, focal extraprostatic extension, two small positive margins

PSA undetectable for 8 months, then 2/6/2009-0.10, 4/26/2009-0.17, 5/22/2009-0.20, 6/11/2009-0.27

Salvage IMRT + 6 Months ADT: Casodex started 6/12/2009, Lupron 6/22/2009, PSA 6/25/2009-0.1, T=516, 7/23/2009-<0.05, T<10, IMRT to start mid-Aug


laughingagain
New Member


Date Joined Oct 2009
Total Posts : 12
   Posted 10/25/2009 10:31 PM (GMT -6)   
 
Barry -
Wondering how your September test turned out.  Hoping for no increases for you.  -Lalughingagain


chinito
Regular Member


Date Joined Dec 2008
Total Posts : 28
   Posted 7/10/2010 11:24 AM (GMT -6)   
The surgeon met with my husband and I after our 3rd consecutive rise in PSA post op in less than a year. we went from .50 to .102 in a little over 6 months and she said that the less than 6 months doubling time was concerning and that it usually indicates that it is not localized but would rather start with radiation first anyway as hormone therapy only suppresses. this is a bit confusing to me. any thoughts out there
Age 56
DOB 9/02/52
DX Prostate Cancer 12/2/08
Double Bypass Heart Surgery 8/08
Gleeson Score 3+4=7
9 out of 12 cores were postive
PSA was 7.71 rose to 12.2 week of surgery
DaVinci surgery 2/06/09
Cath out 2/17/09
Path staging PT2c Bilateral disease, stage 11
PERINEURAL INVASION, present and extensive
vENOUS (large vessel) absent
LYMPHATIC (SMALL VESSEL) invasion SUSPICIOUS FOR LYMPHOVASCULAR INCASION (C5, C10, C20) (16) no evidence of malignancy
ADDITIONAL PATHOLOGIC FINDS High grade prostatic intraepithelial neoplasia, which is extensive
3 month post op PSA undetectable
6 month post op PSA undetectable
10 month post op PSA rose to .050 need to return for more testing


chinito
Regular Member


Date Joined Dec 2008
Total Posts : 28
   Posted 7/10/2010 11:26 AM (GMT -6)   
my updated profile didnt take so am replying again to see if it shows, if not it was
12/29/09 post op PSA .050
3/21/10 PSA .63
7/6/10 PSA .102
Age 56
DOB 9/02/52
DX Prostate Cancer 12/2/08
Double Bypass Heart Surgery 8/08
Gleeson Score 3+4=7
9 out of 12 cores were postive
PSA was 7.71 rose to 12.2 week of surgery
DaVinci surgery 2/06/09
Cath out 2/17/09
Path staging PT2c Bilateral disease, stage 11
PERINEURAL INVASION, present and extensive
vENOUS (large vessel) absent
LYMPHATIC (SMALL VESSEL) invasion SUSPICIOUS FOR LYMPHOVASCULAR INCASION (C5, C10, C20) (16) no evidence of malignancy
ADDITIONAL PATHOLOGIC FINDS High grade prostatic intraepithelial neoplasia, which is extensive
3 month post op PSA undetectable
6 month post op PSA undetectable
10 month post op PSA rose to .050 need to return for more testing


geezer99
Veteran Member


Date Joined Apr 2009
Total Posts : 990
   Posted 7/10/2010 2:28 PM (GMT -6)   
I don't have much to add except to say that I am sorry to hear that you are in that gray area of rising PSA.

Don't hit yourself over the head about your diet. At best, diet is a minor issue in the return of PCa and it is hard to believe that you have been harmed by your eating. You are not in control of what is happening in your body but you are in control of how your mind reacts. Even with rising PSA you have time to think and judge -- and you have time to remember that life is moire than a PSA number

I hope for the best for you whatever that may be.
Age at diagnosis 66, PSA 5.5
Biopsy 12/08 12 cores, 8 positive
Gleason 3+4=7
CAT scan, Bone scan 1/09 both negative.

Robotic surgery 03/03/09 Catheter Out 03/08/09
Pathology: Lymph nodes & Seminal vesicles negative
Margins positive, Capsular penetration extensive Gleason 4+3=7
6 weeks: 1 pad/day, 1 pad/night -- mostly dry at night.
10 weeks: no pad at night -- slight leakage day/1 pad.
3 mo. PSA 0.0 - now light pads
6 mo. PSA 0.00 -- 1 light pad/day
9 mo. PSA 0.00 -- 1 light pad/day ED remains
12 mo. PSA 0.00 -- still one light pad and ED

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