Problems after salvage radiation

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maldugs
Veteran Member


Date Joined Jun 2007
Total Posts : 784
   Posted 8/23/2009 7:01 PM (GMT -6)   
Hi everyone, would like to know if the guys who have had salvage radiation, have had bowel probs after the radiation. Soon after I completed the radiation I was frequently going to the toilet, and had to be near one when I was out, sometimes 5-6 times a day, the urgency has diminished somewhat over the last 18 months, and now I only go 2-3 times a day, usually in the morning,I have a lot of wind build up overnight also.

Obviously the radiation has caused this, my Oncologist told me that the bowel could be scarred in the prostate area, the Doc suggested I have a colonoscopy, but think I will see how things settle down over the next 6 months, spoke to another man who had the radiation 3 years ago, and he said it took him nearly 2 years to settle down.

Any input would be appreciated.

Regards Mal.
age 67 PSA 5.8 DRE slightly firm Rt
Biopsy 2nd July 07 5 out of 12 positive
Gleason 3+4=7 right side tumour adenocarcinoma stage T2a
RP on 30th July,

Post op Pathology, tumour stage T3a 4+3=7, microcsopic evidence of capsular penetration, seminal vessels, bladder neck,are free of tumour, lymph nodes clear, no evidence of metastatic malignancy, tumour does not extend to the apical margins.

Post op PSA 0.5 26th Sept.
PSA 23rd Oct.0.5 seeing Radiation Onocologist 31st Oct.
Started radiation treatment on 5th Dec, to continue until 24 Jan. 08.
Finished treatment, next PSA on 30th April.
PSA 30th April 0.4
PSA 30th July 0.5
PSA 27th Oct 0.4 (I am now 68)
PSA 11th March 09 0.5
PSA 3rd Augiust 09 0.6


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 8/23/2009 7:25 PM (GMT -6)   
mal, the problem you describe sounds somewhat typical for the radiation treatments, the length of time you are having them sounds a bit on the long side. But again, the statistics are based on averages. I am glad that at least it has slowly improved for you. It's another case where every person's body is different, and reacts differently to treatments. Hope it continues to get better for you. I worry about that side effect as I contemplate salvage radiation myself.

David in SC
 Age 57, 56 at DX, PSA 7/7 5.8, 7/8 12.3,9/8 14.5
3rd Biopsy Sept 08: Positive 7 of 7 cores, 40-90%, Gleason 7, 4+3
Open RP surgery 11/14/8, Right nerves spared, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
 Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsule, one post. margin, clear lymph nodes 
2009 PSA   2/9 .05, 5/9 .10, 6/9 .11, 8/9 .16
Lastest 7/13 met with Rad. Oncl, considering options, 7/20 Catheter #6 after complete blockage, 8/14 met with Rad Oncl, still talking option, 8/18 - had laser scope surgery to clear blockage, now on Catheter #7
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 


maldugs
Veteran Member


Date Joined Jun 2007
Total Posts : 784
   Posted 8/23/2009 7:51 PM (GMT -6)   
Thanks David, guess there is an upside and downside to any treatment, still in our case you would rather have the radiation and take the chance on the side effects, than not have it, I wish you well.

Regards Mal.
age 67 PSA 5.8 DRE slightly firm Rt
Biopsy 2nd July 07 5 out of 12 positive
Gleason 3+4=7 right side tumour adenocarcinoma stage T2a
RP on 30th July,

Post op Pathology, tumour stage T3a 4+3=7, microcsopic evidence of capsular penetration, seminal vessels, bladder neck,are free of tumour, lymph nodes clear, no evidence of metastatic malignancy, tumour does not extend to the apical margins.

Post op PSA 0.5 26th Sept.
PSA 23rd Oct.0.5 seeing Radiation Onocologist 31st Oct.
Started radiation treatment on 5th Dec, to continue until 24 Jan. 08.
Finished treatment, next PSA on 30th April.
PSA 30th April 0.4
PSA 30th July 0.5
PSA 27th Oct 0.4 (I am now 68)
PSA 11th March 09 0.5
PSA 3rd Augiust 09 0.6


John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4227
   Posted 8/23/2009 8:28 PM (GMT -6)   
Mal,
about 5% of patients undergoing IMRT have long term bowel problems. Many more have symptoms only in the last week or two that are easily controlled by Immodium. I had no problems, but took a teaspoon or Metamusil daily during treatments. I think it makes a major difference if just your prostate is radiated as opposed to having your whole pelvic area radiated.
JohnT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


Doting Daughter
Veteran Member


Date Joined Aug 2007
Total Posts : 1064
   Posted 8/23/2009 8:30 PM (GMT -6)   
Hi Mal! Sorry to hear about the side effects, but hope and pray that the radiation got rid of all remaining cancer cells! My dad had some diarrhea during treatment and he took Imodium and I believe Metamucil and it seemed to clear it up after a couple of weeks he didn't have any problems.
Not to be graphic, but if there is blood in the stool, I know that Radiation Induced Procto-Sigmoiditis can be a side effect from radiation. Also known as RIPS. I think your symptoms sound a lot more mild than RIPS, but I am obviously not a doctor. Keep us posted and good healing to you my friend!!
Father's Age DX 62 (now 64)
Original Gleason 3+4=7, Post-Op Gleason- 4+3=7,
DaVinci Surgery Aug 31, 2007
Focally Positive Right Margin, One positive node. T3a N1 M0.
Bone Scan/CT Negative (Sept. 10, 2007)
Oct. 17 PSA 0.07
Nov. 13 PSA 0.05
Casodex adm. Nov 07, Lupron beg. Dec 03, 2007 2 yrs
Radiation March 03-April 22, 2008- 8 weeks 5x a week
July 2, 08 PSA <.02
Oct. 10, 08 PSA <.02
Praying for a cured dad.

Co-Moderator Prostate Cancer Forum


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 8/23/2009 9:02 PM (GMT -6)   
Mal, you are correct, ultimately, the side effects possibilities of the radiation won't stop me from seeking the radiation treatments once I am totally convinced I need them and working with a radiation oncologist I can deal with.

david in sc
 Age 57, 56 at DX, PSA 7/7 5.8, 7/8 12.3,9/8 14.5
3rd Biopsy Sept 08: Positive 7 of 7 cores, 40-90%, Gleason 7, 4+3
Open RP surgery 11/14/8, Right nerves spared, 4 days hospital, staples out 11/24/8, 5th cath out on 1/19/9
 Pathlogy Report:Gleason 3+4=7, pT2c, 42 grm, tumor 20%, Contained in capsule, one post. margin, clear lymph nodes 
2009 PSA   2/9 .05, 5/9 .10, 6/9 .11, 8/9 .16
Lastest 7/13 met with Rad. Oncl, considering options, 7/20 Catheter #6 after complete blockage, 8/14 met with Rad Oncl, still talking option, 8/18 - had laser scope surgery to clear blockage, now on Catheter #7
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 


Galileo
Veteran Member


Date Joined Nov 2008
Total Posts : 697
   Posted 8/25/2009 3:22 PM (GMT -6)   
I had some problems with proctitis after salvage IMRT. The worst thing was painful bowel movements, but after I got a prescription for Proctofoam, that went away pretty quickly. I had more frequent, looser bowel movements, but Imodium did the trick there. I had to be careful what I ate.
The symptoms got steadily better in the weeks and months afterwards. The peak of problems was probably in the first two weeks after radiation ended.
All the details you'd care to read are in my blog.

I would do it all again in a heartbeat.
Galileo

Dx Feb 2006, PSA 9 @age 43
RRP Apr 2006 - Gleason 3+4, T2c, NX MX, pos margins
PSA 5/06 <0.1, 8/06 0.2, 12/06 0.6, 1/07 0.7.
Salvage radiation (IMRT) total dose 70.2 Gy, Jan-Mar 2007@ age 44
PSA 6/07 0.1, 9/07 and thereafter <0.1
http://pcabefore50.blogspot.com

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