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Azfyrfyter
New Member


Date Joined Aug 2009
Total Posts : 5
   Posted 9/3/2009 11:17 AM (GMT -6)   
My biopsy came back negative today. I just wanted to say thank you to the forum. After reading so many of your stories and the incredible advice I was very well prepared for the worst case scenerio. It's not over, my dad had PC and through hormones and radiation he is cancer free three years later.
 
 My wife couldn't believe how calm I was about the whole thing, but I owe it all to you. I will be checking in and will be watching. Thank you for your support.

55 years old
PSA 6.0 at last physical
Biopsy pending


CPA
Veteran Member


Date Joined Feb 2008
Total Posts : 655
   Posted 9/3/2009 11:24 AM (GMT -6)   
Congratulations on the negative biopsy.  Please continue to be vigilant and monitor your PSA and other symptoms.  With a family history, you need to stay on top of it.  But for now - way to go.  Go out and celebrate.  David

Diagnosed Dec 2007 during annual routine physical at age 55
PSA doubled from previous year from 1.5 to 3.2
12 biopsies - 2 pos; 2 marginal
Gleason 3+3; upgraded to 4+3 post surgery
RRP 4 Feb 08; both nerves spared
Good pathology - no margins - all encapsulated
Catheter out Feb 13 - pad free Feb 16
PSA every 90 days - ZERO's everytime!
Great wife and family who take very good care of me


Azfyrfyter
New Member


Date Joined Aug 2009
Total Posts : 5
   Posted 9/3/2009 11:30 AM (GMT -6)   
Thanks David...I feel a litle guilty like little Miss Mary Sunshine, but I really couldn't have made it this far on the journey w/o everyone here on the forum. I will be vigilant with my PSA and I'll be preaching the PSA to my boys...now 32.
55 years old
PSA 6.0 at last physical
Biopsy pending
 
09-03-09 Biopsy back - Negative.


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 9/3/2009 11:31 AM (GMT -6)   
Hi Azfyrfyter.
Welcome to HealingWell, Congrats on the negative biopsy. I caution you to stay diligent. Biopsy is not a perfect science, so keep a close eye on this and if there is a rise in PSA, then request a more thourough biopsy. There are also new tests out there that can help out ~ PCA3 is a urine test. This has become quite available.

But for now enjoy the good news.

Tony
 Age 47 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Gleason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 11, 2009): <0.1
 
My Journal is at Tony's Blog  
 
STAY POSITIVE!


Azfyrfyter
New Member


Date Joined Aug 2009
Total Posts : 5
   Posted 9/3/2009 11:35 AM (GMT -6)   
Thanks Tony...I'll keep on it and I'll research the PSA3 urine test. I enjoyed your post and thanks for moderating.
55 years old
PSA 6.0 at last physical
Biopsy pending
 
09-03-09 Biopsy back - Negative.


Geebra
Regular Member


Date Joined May 2009
Total Posts : 476
   Posted 9/3/2009 1:09 PM (GMT -6)   
Congrats on negative biopsy. I think you need to get a rational explaination to high PSA. Do you have enlarged prostate? Did biopsy show inflamation? Absent the explaination keep digging. Maybe an MRI is in order. I had five or six negative biopsies before they found the cancer. I wish I did not just wait for the next one every time. There are other tests, saturation biopsies, etc. Get an answer from your doc as to why PSA is so high.

Greg

Father died from poorly differentiated PCa @ 78 - normal PSA and DRE

5 biopsies over 4 years negative while PSA going from 3.8 to 28

Dx Nov 2007, age 46, PSA 29, Gleason 4+4=8

Decided to participate in clinical trial at Duke - 6 rounds of chemo (Taxotere+Avastin)

PSA prior to treatment on 1/8/2008 is 33.90, bounced on 1/31/2008 to 38.20, and down at the end of the treatment (4/24/2008) to 20.60

RRP at Duke (Dr. Moul) on 6/16/2008, Gleason downgraded 4+3=7, T3a N0MX, focal extraprostatic extension, two small positive margins

PSA undetectable for 8 months, then 2/6/2009-0.10, 4/26/2009-0.17, 5/22/2009-0.20, 6/11/2009-0.27

Salvage IMRT + 6 Months ADT: Casodex started 6/12/2009, Lupron 6/22/2009, PSA 6/25/2009-0.1, T=516, 7/23/2009-<0.05, T<10, IMRT to start mid-Aug


MrGimpy
Veteran Member


Date Joined Jul 2009
Total Posts : 504
   Posted 9/3/2009 1:41 PM (GMT -6)   
Thats great news

For the heck of it, see if you can get some Trimix anyway, there is no way to describe the 2 hr non-stop action one gets from this magical shot, Its definitely worth a shot !!!
Stats:
Age: 52
PSA (2008)=1.9
Biopsy on Jan 09, 2009
One (1) out of twelve (12) cores was positive, plus external nodule found
Gleason Score = 3+3
Surgery (Da Vinci, robotic prostatectomy): 4/7/09
Removed Catheter: 04/19/09
100% bladder control - Pad free 7/09
PSA 7/09 undetectable, under .0


Ed C. (Old67)
Veteran Member


Date Joined Jan 2009
Total Posts : 2458
   Posted 9/3/2009 1:41 PM (GMT -6)   
Congratulations! I hope you never have to go thru what we all have been thru. Keep that PC away.
Age: 67 at Dx on 12/30/08
PSA 9/05 1.15; 8/06 1.45; 12/07 2.41; 8/08 3.9; 11/08 3.5 free PSA 11%
2 cores out of 12 were positive Gleason (4+4) and (4+5)
Negative CT scan and bone scan done on 1/16
Robotic surgery performed 2/9/09 Dr Fagin, Austin TX
Pathology report:
Prostate weighed 57 grams size:5.2 x 5.0 x 4.9 cm
Posterior lateral lesions measuring 1.5 x 1.4 x 1.0 cm showing focal capsular penetration over a distance of 3mm.
Prostatic adenocarciroma accounts for approx. 10-20% of the hemisphere.
Gleason 4+4
both nerve bundles removed,
pT3a Nx Mx, Negative margins
seminal vesicles clean, lymph nodes: not dissected
continent after 4 months
8 weeks PSA test 4/7/09 result <0.1
5 months PSA test 7/9/09 result <0.1


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 9/3/2009 2:38 PM (GMT -6)   
Az, congrats, and no need to feel guilty, this is one club you don't want to belong too. Glad you found us, glad we helped prepare you just in case. Hope it stays that way for the rest of your life. My best to your dad too.

David in SC

Azfyrfyter
New Member


Date Joined Aug 2009
Total Posts : 5
   Posted 9/3/2009 2:59 PM (GMT -6)   
Greg, I will continue. I did have right side enlargement on DRE. My Urologist is going to hold off on prescription meds for now, but I will keep exploring the reason for the high PSA. I have also radically changed my diet to try and keep my prostrate healthy. Thanks for the advice.
55 years old
PSA 6.0 at last physical
Biopsy pending
 
09-03-09 Biopsy back - Negative.


Azfyrfyter
New Member


Date Joined Aug 2009
Total Posts : 5
   Posted 9/3/2009 3:01 PM (GMT -6)   
Mr. Gimpy...still have ED to contend with...maybe Trimix is the answer. I tried Viagra...didn't like the way I felt the next AM. Cialis is a little better.
55 years old
PSA 6.0 at last physical
Biopsy pending
 
09-03-09 Biopsy back - Negative.


John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4227
   Posted 9/3/2009 4:19 PM (GMT -6)   
Azfyrfyter,
Geebra is absoultely spot on. You need an explaination for your high PSA. The prostate volume in cc multiplied by 0.066 will give you the amount of normal psa. The doctor should have measured your prostate when he did the biopsy. Any psa that is higher should be suspect. Don't stop looking until you find a doctor that can give you an answer.
JohnT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT

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