It seems as though the cancer is outside the target area of the radiation. This isn't great news at all. You may have some time to continue to watch this, but I would ask questions about
CTC, PAP, and a bone scan to see if it can be determined if this disease is back and androgen independent. If it is, then it's time to look into clinical trial and chemo. Your hubby may be qualified for the MDV3100 phase III trial by Medivation as well. It just started and is being tested with chemotherapy. He may have to do the chemo first if I recall.
It's nice to finally know your name. I know this looks bad but it might be put through a better scrutiny with a second opinion. Certainly stay positive and hopeful. There is lots that can still be done...
Age 47 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Gleason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 11, 2009): <0.1