psa still rising

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Regular Member

Date Joined Jan 2009
Total Posts : 100
   Posted 9/29/2009 4:57 PM (GMT -6)   
 Hello All
Just pick up hubby psa and testosterone test.This is his 2 nd  test after radiation and again the psa   has gone up testoterone gone down .Have a call in to the dr and just waiting to hear.Test result  of the last one was  july 09 psa  0.4 and testosterone 15. sept 09 psa 0.55 testosterone 13. Any one have any thoughts on these numbers.

 my husband age 54 at diagnosis
radical prostateectomy  in 2006
original gleason3+4=7 post op 4+3=7
post op .004
may08 pas0.05
july08 psa 0.09
oct08 psa 0.16
jan09 psa 0.24
start"s radiation on march 12/09(33) in total
july 09 psa 0.4

Tony Crispino
Veteran Member

Date Joined Dec 2006
Total Posts : 8128
   Posted 9/29/2009 7:00 PM (GMT -6)   
Hi Deidre,
It seems as though the cancer is outside the target area of the radiation. This isn't great news at all. You may have some time to continue to watch this, but I would ask questions about CTC, PAP, and a bone scan to see if it can be determined if this disease is back and androgen independent. If it is, then it's time to look into clinical trial and chemo. Your hubby may be qualified for the MDV3100 phase III trial by Medivation as well. It just started and is being tested with chemotherapy. He may have to do the chemo first if I recall.

It's nice to finally know your name. I know this looks bad but it might be put through a better scrutiny with a second opinion. Certainly stay positive and hopeful. There is lots that can still be done...

 Age 47 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Gleason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 11, 2009): <0.1
My Journal is at Tony's Blog  

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