PSA Velocity (high free PSA though), Positive DRE, and negative biopsy

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Fat Sailor
New Member

Date Joined Sep 2009
Total Posts : 7
   Posted 10/13/2009 4:23 PM (GMT -6)   
I posted early about my experience. I'm 47, and during a routine exam The doc found a nodule on the DRE. He ordered a PSA. The PSA jumped from 0.9 to 2.1, but had around 67% free PSA. The PSA test was done ~30min after the DRE, and may have been the culprit for the rise.

A biopsy was done because of the nodule almost two weeks ago.

The doctor called today, and they found no cancer in the 13 cores taken. The first core being targeted on the nodule.

I appreciate greatly this forum and everyone here. The support, advice, and camaraderie here is fantastic and it helped me cope while waiting for the biopsy and results. I don't plan on disappearing. Since I'm going to be monitored by the doc, I'm going to lurk in the background and try and help out where I can.

Veteran Member

Date Joined Sep 2008
Total Posts : 744
   Posted 10/13/2009 4:30 PM (GMT -6)   
Why not do another psa, to confirm the jump was from the DRE?

Veteran Member

Date Joined May 2009
Total Posts : 2691
   Posted 10/13/2009 4:33 PM (GMT -6)   
Glad you can't join our club, but you are certainly welcome to watch !

Did they find any HPINS ? These are pre-cancerous cells.

Two years after my first negative biopsy, I wss diagnosed withy G9 PC.
Age 58, PSA 4.47 Biopsy - 2/12 cores , Gleason 4 + 5 = 9
Da Vinci, Cleveland Clinic  4/14/09   Nerves spared, but carved up a little.
0/23 lymph nodes involved  pT3a NO MX
Catheter and 2 stints in ureters for 2 weeks due to anatomical issues with location of ureters with respect to bladder neck.  Try 3 tubes where no tubes are supposed to be for 2 weeks !
Neg Margins, bladder neck negative
Living the Good Life, cancer free  6 week PSA  <.03
3 month PSA <.01 (different lab)
5 month PSA <.03 (undetectable)

Fat Sailor
New Member

Date Joined Sep 2009
Total Posts : 7
   Posted 10/13/2009 5:21 PM (GMT -6)   
Goodlife - thanks! The doc didn't mention of HPINS. I'm sending the slides to Johns Hopkins for a second opinion, but that will take a few more weeks.

Another PSA will be done in a few more weeks. The doc wants at least a month after the biopsy to let things settle down.

Elite Member

Date Joined Oct 2008
Total Posts : 25355
   Posted 10/13/2009 5:24 PM (GMT -6)   

I am thankful that we can turn down your membership for now. Hope you continue to do well, and join in anytime.
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Latest: 7/09 met 2 rad. oncl, 7/09 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 - out  38 days, 9/14/9 - met 3rd rad. oncl.agree to start radiation, mapping on 9/21/9, 9/24 - mtg with uro/surg, 9/29- pre-op, 10/1 - 3rd corr. surgery - suprapubic cath/hard dialation, 10/5 - began IMRT SRT - 39 sessions/72 gys.

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