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Posted 10/17/2009 10:33 AM (GMT -7)
John's urologist called this morning (on a Saturday) to say that John's PSA is back down to UNDETECTABLE! I think this has only been the second time in my life that I was absolutely speechless.

Of course, we are not going forward with RT at this time but will have the CT scan of John's chest on Tuesday as planned because we need to investigate the spot. But, our urologist said that in light of John's PSA (or lack of it at this point), the spot - whatever it may be - is not related to PCa but we have to check it out.

The urologist already spoke to our rad onc and told her the good news so, for now, we do nothing. The next PSA is in early December - if it still comes back as undetectable, we go back to a 3 month follow-up.

I wanted to share this with all of you for two reasons: to share the good news, and to let those of you who are in similar situations know that miracles do happen! Take heart.
Husband diagnosed in 2/2008 at age 57 with stage T1c. Robotic surgery performed 3/2008. Stage upgraded to T3a (extraprostectic extension in posterior left). Perineural tumor infiltration present. Apex margin, bladder neck and SV negative. Gleason 3+4 (no change from biopsy). PSA results: April 2008 0.1; May 2008 0.0; August 2008 0.0; November 0.0; February 2009 0.0; May 2009 0.0; August 2009 0.1; September 2009 0.3. Met with radiation oncologist and began process for salvage radiation. CT scan and bone scan done on October 8 (bone scan clean!).

Posted 10/17/2009 10:47 AM (GMT -7)
Woohoo! Congrats!
Daughter worried about dad
Locally advanced prostate cancer
CT scan negative
PSA 7.9
Gleeson 7 (3+4)
Age 54
1 postive margin (seminal vesicle)
Robotic nerve sparing surgery Oct 2009
Scheduling for radiation
pt3bpn0mx

Posted 10/17/2009 10:49 AM (GMT -7)
Thank God for miracle. I hope this one is durable. Congratulations! Father died from poorly differentiated PCa @ 78 - normal PSA and DRE 5 biopsies over 4 years negative while PSA going from 3.8 to 28 Dx Nov 2007, age 46, PSA 29, Gleason 4+4=8 Decided to participate in clinical trial at Duke - 6 rounds of chemo (Taxotere+Avastin) PSA prior to treatment on 1/8/2008 is 33.90, bounced on 1/31/2008 to 38.20, and down at the end of the treatment ( 4/24/2008) to 20.60 RRP at Duke (Dr. Moul) on 6/16/2008,  Gleason downgraded 4+3=7, T3a N0MX, focal extraprostatic extension, two small positive margins PSA undetectable for 8 months, then 2/6/2009 - 0.10, 4 /26/2009 - 0.17, 5/22/2009 - 0.20, 6/11/2009 - 0.27 Salvage IMRT + 6 Months ADT: Casodex started 6/12/2009 , Lupron 6/22/2009, PSA 6/25/2009-0.1, T=516, 7/23/2009-<0.05, T<10, IMRT to start mid-Aug
Posted 10/17/2009 11:29 AM (GMT -7)
That is absolutely the best news I've read today. I can't imagine the relief you guys are feeling and I really thank you for sharing your joy with us..
James C. Age 62
Co-Moderator- Prostate Cancer Forum
4/07 PSA 7.6, referred to Urologist, recheck 6.7
7/07 Biopsy: 3 of 16 PCa, 5% involved, left lobe, GS 3/3=6
9/07 Nerve sparing open RRP 110gms.- Path Report: GS 3+3=6 Stg. pT2c, 110gms, margins clear
24 mts: PSA's: .04 each test since surgery, Bimix .3ml PRN or Trimix .15ml PRN

Posted 10/17/2009 11:40 AM (GMT -7)
I can't even begin to imagine the joy you both are feeling right now. My heart is racing for you both and I share in your excitement!! What a miracle indeed!! I will hope and pray that his PSA stays undetectable!! Congrats and I hope you both celebrate tonight!!!
Father's Age DX 62 (now 64)
Original Gleason 3+4=7, Post-Op Gleason- 4+3=7,
DaVinci Surgery Aug 31, 2007
Focally Positive Right Margin, One positive node. T3a N1 M0.
Bone Scan/CT Negative (Sept. 10, 2007)
Oct. 17 PSA 0.07
Nov. 13 PSA 0.05
Casodex adm. Nov 07, Lupron beg. Dec 03, 2007 2 yrs
Radiation March 03-April 22, 2008- 8 weeks 5x a week
July 2, 08 PSA <.02
Oct. 10, 08 PSA <.02
Oct. 9, 09 PSA <.01 Last Lupron Shot
Praying for a cured dad.

Co-Moderator Prostate Cancer Forum

Posted 10/17/2009 12:12 PM (GMT -7)
That is great news.  What has he been eating??????  Or is he just mean and the cancer ran out of his body?

On another note I got arrested in the girls bathroom at Wal-Mart the other day.  After the Dr. told me I was undetectable at my 1 year mark and I thought he meant nobody could see me.   How stupid....

Dx 42

Gleason 6 (tertiary score 0)

OPEN RP 10/08  Johns Hopkins

pT2 Organ confined Gleason 6

PSA Undetectable

Posted 10/17/2009 1:22 PM (GMT -7)
Sephie,

I can't hardly believe your post. You got the miracle that we both knew was possible in theory but didn't really expect. I am so very happy for you and John, he deserved a break, and he's getting it. What a relief to know this.

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Latest: 7/09 met 2 rad. oncl, 7/09 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 - out  38 days, 9/14/9 - met 3rd rad. oncl.agree to start radiation, mapping on 9/21/9, 9/24 - mtg with uro/surg, 9/29- pre-op, 10/1 - 3rd corr. surgery - suprapubic cath/hard dialation, 10/5 - began IMRT SRT - 39 sessions/72 gys.

Posted 10/17/2009 2:24 PM (GMT -7)
This is the ZERO's take root and stay!!!
;o) Linda & Bob
Bob (63) - Laproscopic Prostate Removal Sept 27, 2006 at age 60.

2 of 12 malignant biopsy samples - gleason 3 + 3 = 6.

Pathology - Gleeson 3 + 4; stage T2; cancer completely contained, even a second more aggressive, previously undetected cancer) PSA UNDETECTABLE Nov 2006; Feb, May, Oct 2007; May and November 2008.  Also October 2009  WHOOO HOOOO! THREE YEARS! 
Bob also has two secondary conditions -- Polycythemia (elevated red & white cells & platelets) and . . Myelofibrosis) -- If anyone has experience with or information on these, please email us.

Posted 10/17/2009 2:29 PM (GMT -7)
yeah   yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah yeah .........................Kev
Age 51yrs

DX 11/11/08

6 out of 8 cores positive 3 X 60% / 3 X 10%

PSA 4

Gleason Score 3+4=7

Stage T1c

Robotic Surgery 24/12/08

Upgrade Gleason Score 4+3=7 Gleason Differential 60%/40%

Stage T2c

Three small foci total volume <10%

Neg Margins and Nodes

Nil - Extraprostatic Extentions

Dry less than 1 week.

ED- taking Meds- Its been 9 mnths now getting some action ! yah

PSA 1/09  .03

PSA 2/09  .03

PSA 5/09  .03

PSA 9/09  .03

"Everyday in Everyway I get better"

Posted 10/17/2009 2:44 PM (GMT -7)
Oh WOW! I don't know what the lesson from this is -- perhaps as mundane as don't trust a single PSA test or perhaps as mysterious as miracles happen. But whatever, we rejoice with you and John and wish you a long string of zeros to follow.

ChrisR
I presume that you were in the girl's bathroom because the Boy's doesn't have a pad dispenser. On the other hand, if it is because you completely lack ED we envy your criminal record!
Age at diagnosis 66, PSA 5.5
Biopsy 12/08 12 cores, 8 positive
Gleason 3+4=7
CAT scan, Bone scan 1/09 both negative.

Robotic surgery 03/03/09 Catheter Out 03/08/09
Pathology: Lymph nodes & Seminal vesicles negative
Margins positive, Capsular penetration extensive Gleason 4+3=7
6 weeks: 1 pad/day, 1 pad/night -- mostly dry at night.
10 weeks: no pad at night -- slight leakage day/1 pad.
3 mo. PSA 0.0 - now light pads

Posted 10/17/2009 4:02 PM (GMT -7)
Thanks for all your enthusiastic responses! This has been quite a day - unexpected joys abound! Not only did we find out my my John's latest PSA was back down to zero, but I also got good news about my best girlfriend who was worried about an issue with her mammogram - she's fine! Now, if we can just got those Yankees to clinch the playoffs...

Guys, you are truly some of the best people I know. It really gave me great pleasure to share this good news with all of you - in fact, after our family, you were the next to know. I sincerely hope that there will be more of this kind of news on the boards.

I'll let you all know how the chest CT scan goes on Tuesday.

PS to Chris R: You're a hoot! Took my husband a few seconds to "get" your little joke but it did bring a smile to his face!


Kelli, hope my good news gives you - and everyone here - reason for hope.

You all continue in our prayers.
Sephie and John
Husband diagnosed in 2/2008 at age 57 with stage T1c. Robotic surgery performed 3/2008. Stage upgraded to T3a (extraprostectic extension in posterior left). Perineural tumor infiltration present. Apex margin, bladder neck and SV negative. Gleason 3+4 (no change from biopsy). PSA results: April 2008 0.1; May 2008 0.0; August 2008 0.0; November 0.0; February 2009 0.0; May 2009 0.0; August 2009 0.1; September 2009 0.3. Met with radiation oncologist and began process for salvage radiation. CT scan and bone scan done on October 8. One spot on bone scan (clavicle) being investigated. Third PSA taken on October 16 - PSA IS UNDETECTABLE! Next PSA scheduled for early December. Urged not to begin radiation treatment until it's needed (no problem there!).

Posted 10/17/2009 4:52 PM (GMT -7)
Sephie, I finally have something to disagree with you, how my beloved Red Sox got cheated is beyond me, and the, yuck, Yankees ending up with a better record.

Despite that, I will remain in awe and respect for John's miracle and your friends good news. I will share openly in any one's news, good or bad.

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Latest: 7/09 met 2 rad. oncl, 7/09 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 - out  38 days, 9/14/9 - met 3rd rad. oncl.agree to start radiation, mapping on 9/21/9, 9/24 - mtg with uro/surg, 9/29- pre-op, 10/1 - 3rd corr. surgery - suprapubic cath/hard dialation, 10/5 - began IMRT SRT - 39 sessions/72 gys.

Posted 10/17/2009 5:20 PM (GMT -7)
David ... Red Sox are dirty words in my house (at least for John)...he's a died-hard Yankees fan, growing up in The Bronx in the shadow of the old Yankee Stadium. In fact, he's watching the game now.

Awe and respect are appropriate descriptions for the news we received today. There's no explanation that we or our doctor know of except "it happens". On a more somber note, we are not for one minute letting our guard down and are emotionally prepared if further treatment is in our future.
Husband diagnosed in 2/2008 at age 57 with stage T1c. Robotic surgery performed 3/2008. Stage upgraded to T3a (extraprostectic extension in posterior left). Perineural tumor infiltration present. Apex margin, bladder neck and SV negative. Gleason 3+4 (no change from biopsy). PSA results: April 2008 0.1; May 2008 0.0; August 2008 0.0; November 0.0; February 2009 0.0; May 2009 0.0; August 2009 0.1; September 2009 0.3. Met with radiation oncologist and began process for salvage radiation. CT scan and bone scan done on October 8. One spot on bone scan (clavicle) being investigated. Third PSA taken on October 16 - PSA IS UNDETECTABLE! Next PSA scheduled for early December. Urged not to begin radiation treatment until it's needed (no problem there!).

Posted 10/17/2009 6:01 PM (GMT -7)
That is truly great news! So happy for both of you, but, really...the Yankees?

Greinke for Cy Young.

Bob
 AGE:57

 Dx: October,27(the day after my birthday)

 Psa 14.5

 Gleason:(4+3) 7 T1c

 Bone scan:Negative

 Cat scan: Negative

 Biopsy: 4 of 12 positive, left side, pre-cancerous on the right.

 Confined to prostate.

 DaVinci Jan. 19th, No lymph node involvement, all margins clear.

 8 week PSa <0.01

 Gleason downgraded to (3+4)7

 6 month Psa , 0.1 

 9 month Psa,  0.2  Doubled! Criminy!

 Meet with rad. oncologist 10/15

Posted 10/17/2009 6:05 PM (GMT -7)
Yes, Sephie, one can never let their guard down on the evil PC monster. It lurks and travels to see whom it may devour. But for now, and hopefully a long, long time, John can continue to heal body and soul, and you will have years more to enjoy each other. That would be my personal wish for you guys.

But the Red Sox, sorry ,been a die hard fan since about 1968, that's never going to change with me. The curse of the Bambino was broken in my lifetime, and that was good enough for me.

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Latest: 7/09 met 2 rad. oncl, 7/09 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 - out  38 days, 9/14/9 - met 3rd rad. oncl.agree to start radiation, mapping on 9/21/9, 9/24 - mtg with uro/surg, 9/29- pre-op, 10/1 - 3rd corr. surgery - suprapubic cath/hard dialation, 10/5 - began IMRT SRT - 39 sessions/72 gys.

Posted 10/17/2009 6:06 PM (GMT -7)
Hi Sephie,
I wonder why your numbers only have one place after the decimal. Does the lab you use have finer resolution? I specifically asked the lab resolution before I decided where to take my first 3 month sample. Of course more digits do not necessarily mean more accuracy but it can't hurt.

Anyway congrats! You will both sleep well tonight.
Jeff
DX Age 56. First routine PSA test on April 8th: 17.8.
May PSA: 22.6, 3 weeks later: PSA: 23.2.
Biopsy 6/10/09: 7/12 scores positive, Gleason 6=3+3. Bone scan and C/T scan negative.
RP DaVinci -7/21/2009 @ Univ of Roch Medical Center
Left nerve gone, right partial spared.
Catheter removed - 7/31/2009 Pathology report received:
Gleason 3+4=7 Tumor size: 2.5 x 1.8 cm location: both lobes and apex. No Malignancy in Seminal Vesicle, vasa deferentia, lymph nodes 0/13
Extraprostatic extension present; Perineural invasion: present, extensive
Prostate mass 56 grams. Pathologic Stage: pT3aN0MX
Post Surgery Status:
Potency - 10/05 10 weeks, Still no activity
Incontinence - 8/20 4 full pads per day
. 9/7 3-4 full pads per day (I'm going to try cutting down on fluids. Bad idea. I know.)
9/17 2 months: Still 3 pads per day.
10/5 10 weeks: Still 3 pads per day. At this rate I'll be fine in 2012.
Post Surgery PSA - 9/3 6 weeks- 0.05, 10/13 3 months- 0.004 undetectable.

Posted 10/17/2009 6:47 PM (GMT -7)
Great news Sephie. It always pays to double check. I hope the lung spot is nothing at all.
Age: 67 at Dx on 12/30/08
PSA 9/05 1.15; 8/06 1.45; 12/07 2.41; 8/08 3.9; 11/08 3.5 free PSA 11%
2 cores out of 12 were positive Gleason (4+4) and (4+5)
Negative CT scan and bone scan done on 1/16
Robotic surgery performed 2/9/09 Dr Fagin, Austin TX
Pathology report:
Prostate weighed 57 grams size:5.2 x 5.0 x 4.9 cm
Posterior lateral lesions measuring 1.5 x 1.4 x 1.0 cm showing focal capsular penetration over a distance of 3mm.
Prostatic adenocarciroma accounts for approx. 10-20% of the hemisphere.
Gleason 4+4
both nerve bundles removed,
pT3a Nx Mx, Negative margins
seminal vesicles clean, lymph nodes: not dissected
continent after 4 months
8 weeks PSA test 4/7/09 result <0.1
5 months PSA test 7/9/09 result <0.1

Posted 10/17/2009 7:05 PM (GMT -7)
Jeff, our urologist, regular MD and rad onc are not believers in the ultra sensitive PSA test ... they all said they do not pay attention to any numbers more than one decimal place to the right. John has asked for a more detailed PSA but our urologist's office doesn't use that assay and neither does his regular MD.

I go back and forth as to whether I would want to know the smaller details of his PSA - I have seen too many posts here about guys worrying because their PSA went up from 0.04 to 0.06. I don't think I could live with that knowledge and I think it would make John more anxious than he needs to be. So, we remain with the "standard" PSA test.
Husband diagnosed in 2/2008 at age 57 with stage T1c. Robotic surgery performed 3/2008. Stage upgraded to T3a (extraprostectic extension in posterior left). Perineural tumor infiltration present. Apex margin, bladder neck and SV negative. Gleason 3+4 (no change from biopsy). PSA results: April 2008 0.1; May 2008 0.0; August 2008 0.0; November 0.0; February 2009 0.0; May 2009 0.0; August 2009 0.1; September 2009 0.3. Met with radiation oncologist and began process for salvage radiation. CT scan and bone scan done on October 8. One spot on bone scan (clavicle) being investigated. Third PSA taken on October 16 - PSA IS UNDETECTABLE! Next PSA scheduled for early December. Urged not to begin radiation treatment until it's needed (no problem there!).

Posted 10/18/2009 8:46 AM (GMT -7)
I just got in from church and read this post. WOW is all I know to say. This is awesome news and I so appreciate you sharing it with us. May you have much grace and peace in your day.

love you all
Dale
My PSA at diagnosis was 16.3
age 47 (current)

http://www.caringbridge.org/visit/dalechildress

My gleason score from prostate was 4+5=9 and from the lymph nodes (3 positive) was 4+4=8
I had 44 IMRT's
Casodex
Currently on Lupron
I go to The Cancer Treatment Center of America
Married with two kids
latest PSA 5-27-08 0.11

PSA July 24th, 2008 is 0.04
PSA Dec 16th, 2008 is .016
PSA Mar 30th, 2009 is .02
PSA July 28th 2009 is .01
PSA OCt 15th 2009 is .11

Testosterone keeps rising, the current number is 156, up from 57 in May

T level dropped to 37 Mar 30th, 2009
cancer in 4 of 6 cores
92%
80%
37%
28%

Posted 10/18/2009 11:24 AM (GMT -7)
Wonderful just wonderful fantastic news.  Take the news for what is is and have a great Sunday.

Jeff Travasos

Cajun Country

Jeff T Age 57

9/08 PSA 5.4, referred to Urologist
9/08 Biopsy: GS 3/4=7
10/08 Nerve sparing open RRP- Path Report: GS 3+3=7 Stg. pT2c, margins clear
3 mts: PSA .05 undetectable

 10th month  PSA <0.01

ED- 5 mg Cialis daily, pump daily, going to try MUSE next

Posted 10/18/2009 5:26 PM (GMT -7)
Sephie,
If you look at the blood work order you will see 2 boxes for the PSA "Screening" (the standard type with 1 decimal place or "Diagnostic" which as 2 or more. It seems to me knowledge is always better. IMO, when you are measuring small things you should use a ruler with finer resolution. Leave it up to you to decide whether you want to round to the next digit. If you want to call 0.04 a 0.0 and 0.06 a 0.1 fine. You are willing to accept going from 0.0 to 0.1
I would check to see if the lab you use even has the capability. It's possible your lab does not and that is why your Docs are glossing over it.
I'm willing to bet as long as the lab has the capability there isn't a guy here who wouldn't want to know the truth.
Good luck,
Jeff
DX Age 56. First routine PSA test on April 8th: 17.8.
May PSA: 22.6, 3 weeks later: PSA: 23.2.
Biopsy 6/10/09: 7/12 scores positive, Gleason 6=3+3. Bone scan and C/T scan negative.
RP DaVinci -7/21/2009 @ Univ of Roch Medical Center
Left nerve gone, right partial spared.
Catheter removed - 7/31/2009 Pathology report received:
Gleason 3+4=7 Tumor size: 2.5 x 1.8 cm location: both lobes and apex. No Malignancy in Seminal Vesicle, vasa deferentia, lymph nodes 0/13
Extraprostatic extension present; Perineural invasion: present, extensive
Prostate mass 56 grams. Pathologic Stage: pT3aN0MX
Post Surgery Status:
Potency - 10/05 10 weeks, Still no activity
Incontinence - 8/20 4 full pads per day
. 9/7 3-4 full pads per day (I'm going to try cutting down on fluids. Bad idea. I know.)
9/17 2 months: Still 3 pads per day.
10/5 10 weeks: Still 3 pads per day. At this rate I'll be fine in 2012.
Post Surgery PSA - 9/3 6 weeks- 0.05, 10/13 3 months- 0.004 undetectable.

Posted 10/18/2009 8:48 PM (GMT -7)
Sephie and John.

It's not often I'm at a loss for words, but this news of yours is about as close as I get. Hallelujah, Hallelujah, Halleleujah ! ! !

Sheldon AKA Sleepless
Age 67 in Apil '09 at news of 4 of 12 cores positive T2B and Gleason 3 + 3 and 5% to 25% PSA 1.5

Re-read of slides in June said Gleason 3 + 4 same four cores 5% to 15%

June 29 daVinci prostatectomy, Dr. Eric Estey, at Royal Alexandra Hospital Edmonton one night stay

Flew home to Winnipeg on July 3 after 5 nights in Ramada Inn  ---  perfect recovery spot!

Catheter out July 9, so far, so good

Final pathology is 3 + 4 Gleason 7, clear margins, clear nodes, T2C, sugeron says report is "excellent"

First post op PSA Sept 09  0.02

Oct 1st 09 -- dry at night, during day some stress issues, but better every week.    

Posted 10/19/2009 9:42 AM (GMT -7)
That's great news.

Speechless and happy. Mmmm what a state.

OBB
55 yo
Dx:9/29/09
DRE: Susp
PSA: 3.5
Gleason: 3+4/7
6/12 Cores Positive; Sextants were 1%, 3%, 8%, 15%, 12%, 0%
RALP: 10/10/09
PATH:
Margins: Clear
Lymph Nodes: Clear
Seminal Vesicles: Clear
Gleason: No increase from biopsy 3+4/7
Some perineural and capsule invasion.
T2c,NO,MX

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