Post OP PSA crept up some at 31 month mark...

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pasayten
Regular Member


Date Joined Mar 2007
Total Posts : 437
   Posted 11/2/2009 7:27 PM (GMT -6)   
Hello all
 
Well,  it has been awhile since I have posted...  and things have been going good.  We have moved to Winthrop WA from Monroe, WA  and accordingly changed med facilities...  The house we started in 2006 is down to finishing trimwork...  and we enjoy the environment over there immensely... 
 
As my signature shows,  post op PSA was 0.01 and two followups were 0.02  (thru Dec 2008)
 
Just had PSA taken for annual check-up and even though I told them to use the more accurate test for post op PSA guys like me, they forgot anf the result came back as 0.1  (not <0.1)...  I told them I wanted the more accurate test and they said the lab still had sample and could retest...  that result came back at 0.13... and I am about 31 months post op.
 
So,  since it has crept up, I have left a message for my original surgeon back in Seattle for any followup plans he might want...  and a retest at their lab...   In a post op followup discussions with my original surgeon back in 2008 he had mentioned that he considered below 0.2 as basically undetectable for the tests, but would be interested if there was a consistantly increasing pattern even though results were below that level.  
 
So time for a little concern again...  Amazing how post op and initial results low,  you kind of "forget" about PCA for your own person...  about the drama and feelings of the journey at that time...  and then a unexpected test result can bring it immedately back into the foreground again...  bring that heart rate back up again...  Such is life...   Good that we have friends and places like HW to vent...   :-)
 
We will keep you posted on this new little sidetrail of the journey...
 
God Bless All...
 
pasayten
 
After 3-4 years of annual PSA 4-6, biopsy recommended
3/13/2007 - 12 point biopsy - Left 0/6  Right 1/6 Gleason 3+3 T1c
4/24/2007 - DaVinci performed at Virginia Mason hospital in Seattle
5/2/2007 - Catheter Out! Final pathology of Gleason 6  T2c Nx Mx, approx 20% of prostate involved, positive margin, but only at 2 focal points.  
6/28/2007 9 weeks incontinance... Overnite, went from 4-6 soaked pads a day from prev 8 weeks to 2 barely wet pads a day.
7/12/2007 11 weeks post-op  Minimal leakage...  one small pad a day
7/18/2007 First Post-Op PSA...  0.01 !!! 
9/10/2007 Pad free and ED at 75% with 100mg Viagra generic
6/26/2008 2nd Post-OP PSA at 14 months...  0.02 
12/2/2008 3rd Post-OP PSA at 20 months...   0.02
11/1/2009 4th Post-OP PSA at 31 months...   0.13 (moved and diff lab)


BillyMac
Veteran Member


Date Joined Feb 2008
Total Posts : 1858
   Posted 11/2/2009 7:59 PM (GMT -6)   
payasten,
Although the test results indicate an increasing PSA I would be a little sceptical. Things to think of are was the equipment calibrated initially to yield an ultrasensitve rather than a standard result. Secondly was the sample kept properly between the two tests.........if not stored correctly the sample will be affected. It is a usually problem shifting between labs (different techs, different calibration) so I would get retested ASAP. I always get my GP to mark the test request with the clinical note "progress post-postatectomy". Remember, as run of the mill PSA tests yield a result above 2, the tech running the test may well look at your result and think "that's a good reading for a bloke that age."
Bill
1/05 PSA----2.9 3/06-----3.2 3/07-------4.1 5/07------3.9 All negative DREs
Aged 59 when diagnosed
Biopsy 6/07
4 of 10 cores positive for Adenocarcinoma-------bummer!
Core 1 <5%, core 2----50%, core 3----60%, core 4----50%
Biopsy Pathologist's comment:
Gleason 4+3=7 (80% grade 4) Stage T2c
Neither extracapsular nor perineural invasion is identified
CT scan and Bone scan show no evidence of metastases
Da Vinci RP Aug 10th 2007
Post-op pathology:
Positive for perineural invasion and 1 small focal extension
Negative at surgical margins, negative node and negative vesicle involvement
Some 4+4=8 identified ........upgraded to Gleason 8
PSA Oct 07 <0.1 undetectable
PSA Jan 08 <0.1 undetectable
PSA April 08 <0.001 undetectable (disregarded due to lab "misreporting")
PSA August 08 <0.001 undetectable (disregarded due to lab "misreporting")
Post-op pathology rechecked by new lab:
Gleason downgraded to 4+3=7
Focal extension comprised of grade 3 cells
PSA September 08 <0.01 (new lab)
PSA February 09 <0.01
PSA August 09 (2 year mark), <0.01


biker90
Veteran Member


Date Joined Nov 2006
Total Posts : 1464
   Posted 11/2/2009 8:48 PM (GMT -6)   
Hey Pas,

Hang in there (I know you will). Its a bump in the road but things will smooth out. Its good you are contacting your original doc.

Congrats on getting settled in Winthrop. This side of the mountains has less traffic, less earthquakes, less rain and lots fewer hassles.

Jim
Age 75. Diagnosed 11/03/06. PSA 7.05. Stage T2C Gleason 3+3.
RRP 12/7/06. Nerves and nodes okay.
Catheter out on 12/13/06. Dry on 12/14/06.
Pathological stage: T2C N0 MX. Gleason 3+4.
50 mg Viagra + .03 cc Trimix = Excellent Results
PSAs from 1/3/07 - 7/17/09 zero.
Next PSA - July/2010
Lung cancer dxed on 5/16/08. Surgery on 6/25/08 T1N1M0 - Stage IIA Finished 4 cycles of chemo on 11/7/08.
CT scans on 12/2/08 - 9/22/09 - in remission!!!
Next scan in December 09.
Biker90's Journey
http://www.caringbridge.org/visit/jimrobinson
"Patience is essential, attitude is everything."


pasayten
Regular Member


Date Joined Mar 2007
Total Posts : 437
   Posted 11/3/2009 1:09 AM (GMT -6)   
Hi Biker!
 
Ya...  Chilling out now...   Took a couple of hours to settle down after hearing result and to get back in the ol' PCA "groove"...   Was near a year since last test and caused me to nearly forget I was am cancer survivor...    And the need for due dligence in continued monitoring and management.  It is a minor bump for concern and that is it...  Nothing compared to status and sruggles of many others on here...  and some of our friends...  we have 2 families we know in Winthrop that have children struggling right now...  and who are also on the caringbridge site...  :-(
 
Other than this,  we are really loving the eastside....   It is always so "bright" out!   Spent the first 60 years of my life surrounded by tall fir trees in Monroe or big city buildings in Seattle...  lol...
 
Tons of pictures posted at http://photos.peteavis.com
 
Liking your continued "remission" status on the Lungs and the 0's for PSA...  :-)
Keep it up!
 
God Bless and take care Jim...  
Hugs also to Mary Lu...
 
pasayten

pasayten
Regular Member


Date Joined Mar 2007
Total Posts : 437
   Posted 11/3/2009 1:13 AM (GMT -6)   
Thanks for the post BillyMac,

Yes, I am a little unsure of the latest lab result and will get a new test at my original doctor's location tomorrow... Then go from there... Just a wake up call... Started to take things for granted... I do that sometimes...

Take care...

pasayten
After 3-4 years of annual PSA 4-6, biopsy recommended
3/13/2007 - 12 point biopsy - Left 0/6  Right 1/6 Gleason 3+3 T1c
4/24/2007 - DaVinci performed at Virginia Mason hospital in Seattle
5/2/2007 - Catheter Out! Final pathology of Gleason 6  T2c Nx Mx, approx 20% of prostate involved, positive margin, but only at 2 focal points.  
6/28/2007 9 weeks incontinance... Overnite, went from 4-6 soaked pads a day from prev 8 weeks to 2 barely wet pads a day.
7/12/2007 11 weeks post-op  Minimal leakage...  one small pad a day
7/18/2007 First Post-Op PSA...  0.01 !!! 
9/10/2007 Pad free and ED at 75% with 100mg Viagra generic
6/26/2008 2nd Post-OP PSA at 14 months...  0.02 
12/2/2008 3rd Post-OP PSA at 20 months...   0.02
11/1/2009 4th Post-OP PSA at 31 months...   0.13 (moved and diff lab)


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 11/4/2009 11:22 AM (GMT -6)   
Hi Pasayten,
Good to see you again, though I wish it was just to say hello. But a rising PSA is not the end of all things by a large amount. Since you have a new lab a retest is in order. But if you need the radiation, you know I did well, as have so many guys here.

Stay well, and stay positive!

Tony
Age 47 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Gleason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
Hormone Therapy May '07 to September '09 ~ Currently off.
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (October 7, 2009): <0.1

My journey is at: www.caringbridge.org/visit/tonycrispino

My InfoLink page is at Tony's Prostate Cancer InfoLink Page

STAY POSITIVE!


pasayten
Regular Member


Date Joined Mar 2007
Total Posts : 437
   Posted 11/4/2009 8:37 PM (GMT -6)   
Hi Tony,
 
Thanks for the words...   I am doing fine today...   Venting and researching the info helps alot...  Now fully back in the groove... 
 
BTW,  the retest at original lab came back at 0.11,  (other lab was 0.13) so I am also getting an idea about test variabilities...  My original DaVinci doc has me scheduled for a followup 11/10.
 
Read your CaringBridge journal...  The reason I went in for my checkup was for cholestorel...  Our family has high levels and mother, brother, and sister are on meds for it...   Mine showed at 260...   time to put me on meds also (simvastatin)...   I had been hanging around at the 220 level for last 5 years... and with a lot of "good" chol...  so meds were not indicted at that time...   So,  we have that in common now also...  :-)
 
Take care!   
 
pasayten
After 3-4 years of annual PSA 4-6, biopsy recommended
3/13/2007 - 12 point biopsy - Left 0/6  Right 1/6 Gleason 3+3 T1c
4/24/2007 - DaVinci performed at Virginia Mason hospital in Seattle
5/2/2007 - Catheter Out! Final pathology of Gleason 6  T2c Nx Mx, approx 20% of prostate involved, positive margin, but only at 2 focal points.  
6/28/2007 9 weeks incontinance... Overnite, went from 4-6 soaked pads a day from prev 8 weeks to 2 barely wet pads a day.
7/12/2007 11 weeks post-op  Minimal leakage...  one small pad a day
7/18/2007 First Post-Op PSA...  0.01 !!! 
9/10/2007 Pad free and ED at 75% with 100mg Viagra generic
6/26/2008 2nd Post-OP PSA at 14 months...  0.02 
12/2/2008 3rd Post-OP PSA at 20 months...   0.03
10/30/2009 4th Post-OP PSA at 31 months...   0.13 (moved and diff lab)
11/3/2009 Retest at my original lab...  0.11  (followup with Doc sched 11/10)

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