Rapid rise of PSA

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New Member

Date Joined Nov 2009
Total Posts : 1
   Posted 11/6/2009 3:53 PM (GMT -6)   
I am 71 y.o. and had radical prostestomy in 1992. PSA has risen intermidentaly since surgery. Have had intermidant hormone therapy (Zoladex) when PSA rose above 6-7 for past 6 years.
Neglected to have blood test to check PSA for 12  months and most recent PSA was 115.
Anybody had this experience and have any informed comments about the rapid rise in PSA?

Elite Member

Date Joined Oct 2008
Total Posts : 25355
   Posted 11/6/2009 3:58 PM (GMT -6)   
Welcome to HW, Bee. My that is some serious psa rise some 7 years after your surgery. What is your doctor telling you? You said you have been on some form of HT for the past six years, hopefully that would have helped keep your psa in check, and it didnt. Have you had any recent bone scans to see if there is any evidence of PC spread?

Please keep us closely posted.

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out  38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - began IMRT SRT - 39 sess/72 gys cath #8 33 days, 11/2- SP Cath #9 in place

Veteran Member

Date Joined Apr 2008
Total Posts : 1382
   Posted 11/6/2009 6:24 PM (GMT -6)   
I agree with David I would hope by now you have either seen your doctor or have a visit scheduled very soon. This is a serious matter and should be dealt with accordingly. Do not let this go any longer. Please keep us posted on how you are doing and welcome to HW.

peace and love
My PSA at diagnosis was 16.3
age 47 (current)


My gleason score from prostate was 4+5=9 and from the lymph nodes (3 positive) was 4+4=8
I had 44 IMRT's
Currently on Lupron
I go to The Cancer Treatment Center of America
Married with two kids
latest PSA 5-27-08 0.11

PSA July 24th, 2008 is 0.04
PSA Dec 16th, 2008 is .016
PSA Mar 30th, 2009 is .02
PSA July 28th 2009 is .01
PSA OCt 15th 2009 is .11

Testosterone keeps rising, the current number is 156, up from 57 in May

T level dropped to 37 Mar 30th, 2009
cancer in 4 of 6 cores

Veteran Member

Date Joined Dec 2008
Total Posts : 3149
   Posted 11/6/2009 7:00 PM (GMT -6)   
Not enough information herein to give you alot of heads up, but if you are on LHRH drug now, like zoladex or lupron etc. and your psa is at this level, then you need a PCa oncologist and another type of drug therapy to atleast try on. Alot of various drugs and protocols can be used to get new results against PCa and drop that psa(give some control over PCa) atleast for some duration of time and that can vary greatly from patient to patient. Assumingly if you do nothing it will keep rising and or maybe be doubling within 6 months or less and if so.....omnious future expections as to bone and other tissues having mets present, but still can respond to new therapies...how long is always the biggest unknown and question. Get busy looking at everything out there is in your best interests.
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