Penile injections

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New Member

Date Joined May 2009
Total Posts : 8
   Posted 11/8/2009 9:36 PM (GMT -6)   
Do the trimix injections help to infuse blood into the 1/3 of the penis inside the body, or is it like the pump and only causes blood to flow into the out of body 2/3's?
The pump gives my outer 2/3 a nice erection, but nothing to hold the sign post up in the air without any blood backing it up in the
1/3 inside me.
Any comments on this?  

Gleason, 4+3; PSA, 7
Robotic Prostatectomy 4/09, nerves both sides spared, post surgery analysis confirmed 3+4 Gleason,
cancer contained, no penetration, lymph nodes clear
6 week and 4 month PSA <0.1, continent at 4 months. Impotent at 4 months still. No nocturnal erections.



Veteran Member

Date Joined May 2009
Total Posts : 2692
   Posted 11/8/2009 9:39 PM (GMT -6)   
It is better than the pump, and is an aid to the pump, but don't look for a flagpole like you had when you were 17. It also appears that some men have a better reaction than others.
Age 58, PSA 4.47 Biopsy - 2/12 cores , Gleason 4 + 5 = 9
Da Vinci, Cleveland Clinic  4/14/09   Nerves spared, but carved up a little.
0/23 lymph nodes involved  pT3a NO MX
Catheter and 2 stints in ureters for 2 weeks .
Neg Margins, bladder neck negative
Living the Good Life, cancer free  6 week PSA  <.03
3 month PSA <.01 (different lab)
5 month PSA <.03 (undetectable)
6 Month PSA <.01
1 pad a day, no progress on ED.  Trimix injections

Veteran Member

Date Joined Nov 2007
Total Posts : 598
   Posted 11/8/2009 10:17 PM (GMT -6)   
The entire penis, including the bulb, will be engorged. Many men find they have great erections with injections. Lots of guys feel like they are 19 again.
46 at Diagnosis.
Father died of Pca 4/07 at 86.
10/07 PSA 5.06 (Biopsy 11/07 1 of 12 with 8% involvment) (1mm)
Da Vinci surgery Jan 5, '08 at Mt. Sinai Hosp. NYC
Saved both nerve bundles.
Path Report: Stage T2cNxMx
-Gleason (3+3)6
Pad free on March 14 - (10 weeks.) Never a problem since.
ED - at one year, ED is fine with viagra.
One year PSA - undectable!

ED Website: - frank discussions of Erectile Dysfunction - check it out.

Regular Member

Date Joined Dec 2008
Total Posts : 377
   Posted 11/8/2009 10:25 PM (GMT -6)   
I gave up on the VED, never could get the darn thing to work right. The trimix/bimix injection fills up the whole penis. Injection is pretty easy, the most difficult thing is getting the dosage right. Too little, nothing happens, too much, off to the ER you go. If using trimix start out low and increase by 3 units with each subsequent injection. Be conservative. You are trying to avoid the 4+ hour erection syndrome. Keep lots of sudafed available to bring it down just in case you over shoot.............
my age=52 when all this happened,
PSA went from 1.9 to 2.85 in one year, urologist ordered biopsy,
First biopsy on 03/08, "suspicious for cancer but not diagnostic"
Second biopsy on 08/14/08, 2/12 cores positive on R side, 1 core=5% Ca, other core = 25% Ca, Gleason Score= 6 both cores,
Clinical Stage T1C
Bilateral nerve sparing Robotic Surgery on 09/11/08, pathological stage T2A at surgery
No signs of spread, organ contained,
3 0's in a row now, 10 months out
Incontinence gone in early December '08,
ED remains,  still taking daily viagra for penile rehab, uro said try oral meds and then trimix for sex only now, Peyronie's Disease a problem now

Regular Member

Date Joined Oct 2009
Total Posts : 135
   Posted 11/8/2009 10:36 PM (GMT -6)   
My experience with the injections, and mind you the injectable medication that I take is Phentalamine & Prostagladin E, with a little Lidocaine for the pain, does appear to perform much better than the VED pump, which gave me the "hinge" effect. This "hinge" effect for me was not a functional solution for intercourse. It was like trying to stuff a limp sausage into a garden hose, so to speak. The injections do affect the entire penile tissues, including those located within the pubic region, so no longer is there a hinge affect. What is a problem, is getting the medication dosage titrated so that the degree of pain that occurs about 1/2 hour after the injection is decreased. And so far, we have not gotten the dosage correct so that the erection is functional, and the severe pain is absent. It seems that when I inject adequate amounts of medication to create a functional, useable erection, then I get so much pain, that it completely detracts from the whole purpose of performing sex. But we (my wife and I ) are still working on that and hope to get all issues resolved soon !
RRP May 04, 2009
Pre-op Gleason 6
Post-op Gleason 7

Veteran Member

Date Joined May 2009
Total Posts : 739
   Posted 11/9/2009 8:00 AM (GMT -6)   
mspt, have you had to go to the ER? I wonder what happens if you get one of those 4 hour erections and go to the ER. Do they see you quickly, or do you have to sit there for hours on end waiting to be seen?
Age 64 yrs
DX 5/2009
8 out of 12 cores positive
PSA 5.6
Gleason Score 3+4=7
Stage T2a
Da Vinci Surgery 08/07/2009
Upgrade Gleanson Score 4+3=7
Stage pT2c
Neg Margins and Nodes
Extracapsular extension noted but neg Extraprostatic Extention
Dry immediately
First PSA 11/3/09 <0.1

Veteran Member

Date Joined Jul 2009
Total Posts : 504
   Posted 11/9/2009 8:28 AM (GMT -6)   
Using Trimix I get exactly the same flag pole erection as before surgery as long as I am aroused

If I am not aroused, the head is not completely filled, but the shaft is still rock hard, a bit of forplay and presto back to 100% at the tip

Great erection inside the VED but as soon as I deflated the air the erection would subside, never tried the rings though
Age: 52
PSA (2008)=1.9
Biopsy on Jan 09, 2009
One (1) out of twelve (12) cores was positive, plus external nodule found
Gleason Score = 3+3
Surgery (Da Vinci, robotic prostatectomy): 4/7/09
Removed Catheter: 04/19/09
100% bladder control - Pad free 7/09
PSA 7/09 undetectable, under .0

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