Another Test for PCa -You learn something new every day

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Veteran Member

Date Joined Aug 2009
Total Posts : 2447
   Posted 11/9/2009 10:39 PM (GMT -6)   
I had the pleasure of talking on the phone this evening with a guy who has just joined HW. Something I said in one of my posts prompted him to email me about talking with me personally.

He is on his on search for answers to PCa and the right approach for him. I very much enjoyed the conversation.

During the conversation he mentioned that his 2nd opinion Urologist suggested prior to doing a biopsy that they conduct a PCA3 test.

I have to admit I had not heard of it before. Now maybe it has been discussed here at HW before, but it must have been before I joined.

At any rate here is a link discussing it and to me it looks promising and NON-INVASIVE.

What do you guys know about this and/or think about it?


61 years old
PSA 11/07 3.0
PSA 5/09 6.4
Diagnosis confirmed July 9, 2009
12 Needle Biopsy = 9 clear , 3 postive
<5%, 90%, 40%
Gleason Score (3+4) 7 in all positive cores
CT Organ Scan - negative
Nuclear Bone Scan - Negative

da Vinci 9/17/09 Dr. Mani Menon Henry Ford Medical Institute

Post Surgery Pathology:
Gleason: Changed to (4+3) = 7
Stage: T3a
Tumor Volume 12.5%
Margins: focally positive right posterior mid level
Perineural Invasion: present
Seminal Invasion: absent
Venous Invasion: absent
Angiolymphatic Invasion: absent
Left Internal iliac lymph node: reveals zero
Right Internal lymph node: reveals zero

Veteran Member

Date Joined Aug 2009
Total Posts : 2447
   Posted 11/10/2009 7:05 AM (GMT -6)   
For the researchers and commentators in all of us, here is an additional site I found about the PCA3 testing and trials being done.

If this is in fact a valid trial and more specific mechanism in diagnosing PCA, it may save many in the future from needless biopsies and treatments.


Veteran Member

Date Joined Dec 2008
Total Posts : 3149
   Posted 11/10/2009 8:43 PM (GMT -6)   
Dr. Bostwick uses this and it has actually been around for years, it had different abbreviation in the earilier days. Search Bostwicks website and read about it. Great for someone whom wishes to avoid biopsies atleast for a while, while analyzing these test results. Hey I met Dr. B. at a PCa meeting here in Michigan many years ago now, fab-u-lous doc and passionate about PCa and answering questions.  He is one of the best pathologist you will find.

Post Edited (zufus) : 11/10/2009 7:48:00 PM (GMT-7)

Veteran Member

Date Joined Aug 2009
Total Posts : 2447
   Posted 11/10/2009 8:53 PM (GMT -6)   

The gentlemen I referred to has just posted his story on HW. compilier is his name. It will be interesting to follow his story and see how the PCA3 works out for him.

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