Great question Defender,
I spent a little while reading up on PSA3 and its genetic marker and it left me like you, wondering what it would accomplish.
Let's say you do the test. It will likely show you have a genetic disposition to PCa. Unless you are considering only a vasectomy would that change your treatment decision in any way? What if it shows you don't have the marker? You already have PC. So if the test outcome will not affect your decision why do it? Unless you are doing it as a control study for science I don't see the point.
This test seems like a neat way to identify people who might have PCa down the road. I hope employers never use this to screen for employees with potential health issues. A slippery slope indeed.
Maybe someone else sees something we're missing.
Good luck with whatever you decide.
DX Age 56. First routine PSA test on April 8th: 17.8.
May PSA: 22.6, 3 weeks later: PSA: 23.2.
Biopsy 6/10/09: 7/12 scores positive, Gleason 6=3+3. Bone scan and C/T scan negative.
RP DaVinci -7/21/2009 @ Univ of Roch Medical Center
Left nerve gone, right partial spared.
Catheter removed - 7/31/2009 Pathology report received:
Gleason 3+4=7 Tumor size: 2.5 x 1.8 cm location: both lobes and apex. No Malignancy in Seminal Vesicle, vasa deferentia, lymph nodes 0/13
Extraprostatic extension present; Perineural invasion: present, extensive
Prostate mass 56 grams. Pathologic Stage: pT3aN0MX
Post Surgery Status:
Potency - 10/31 3 months, Still no activity, nada, zip
Incontinence - 8/20 4 full pads per day
. 9/7 3-4 full pads per day (I'm going to try cutting down on fluids. Bad idea. I know.)
9/17 2 months: Still 3 pads per day.
10/31 14 weeks: Still 3 pads per day. At this rate I'll be fine in 2012.
Post Surgery PSA - 9/3 6 weeks- 0.05, 10/13 3 months- 0.04 undetectable.