Let me summarize and then I have some questions.
I had my routine physical in August. Unfortunately, I was informed my PSA test was 4.01.
I was put on an antibiotic for a few months and then retested. Ideally, if it is an infection, the PSA would go down. Mine went up to 4.19. They also did a "free PSA" test. This is more specific for cancer. Ideally, you want a number above or equal to 25. Mine was 24. Once again, not good, but all of the above numbers were in a grey area. But the fact that my PSA 18 months ago was 2.97 and that the last PSA went up even after the antibiotics was not good.
I then went to Univ. of Mich. hospital for a second opinion. They have a brand new test, the PCA-3, that is really specific for prostate cancer. 35 is the cutoff point there. Higher than 35 is not good. I just got the bad news today. Mine was 75.9, which is just not good at all.
None of the above is diagnostic, but it is suggestive. I have to undergo a prostate biopsy and do it quickly. Now, this is interesting. I indicated that I would like to get the happy juice (ie: the colonoscopy type of sedation) for the procedure as I am feeling rather wimpy about all of this. The doctor didn't really want to do it that way, but would. Anyway, she talked me into not going that way. I then had to talk to scheduling I want it done ASAP. Well, I could get it done on 12/18 or they can squeeze me in on 12/11, OR if I want the sedation, they can do it in the OR on 11/30! That convinced me! I'm doing it on 11/30.
Now for my questions. I usually do my own research but I am now in scared panic mode and I am just not thinking clearly. First, is there still a decent chance that I do NOT have PC? It appears from the research I did that there is about a 55% chance of a positive biopsy. It seems if the PCA-3 test is that good, there would be a much higher probability, so maybe I didn't read it right (this was awhile and I am having problems finding the reference again). Can someone help me out on this? Also, we know that biopsies can certainly miss cancers, so saying there is a 55% chance of a positive biopsy does not mean there is a 55% chance you have cancer. Am I correct? Wouldn't it be much higher?
Finally, I am now worried about having aggressive cancer, based on that stunning number. I recall reading that they hope to use the PCA-3 to find aggressive cancers, but I'm not sure if they quantified any of that or maybe they even meant subsequent to one positive biopsy?
I'd appreciate any information.
PSA-- 3/08--2.90; 8/09--4.01; 11/09--4.19 (Free PSA 24%), this after 45 days on cipro!
History of BPH/prostatitis.
Awaiting results of my PCA-3 test which will determine whether a biopsy is in my immediate future