Elevated PSA and prostate issues .. are they related to Lyme disease?

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fathers son
New Member

Date Joined Nov 2009
Total Posts : 8
   Posted 11/29/2009 7:01 PM (GMT -6)   
I will be seeing a urologist because of an elevated PSA. Interestingly, I just finished 3 weeks of doxycyclene after being tested and deemed positive for Lyme.( I will post this is the Lyme board as well)..but very curious if anyone is familiar with any linkage between Lyme, PSA elevation of prostate disease?
( I have been waking up a couple times a night to urinate since being treated).. Odd and new.
Thx in advance.

Veteran Member

Date Joined Sep 2009
Total Posts : 3172
   Posted 11/29/2009 7:27 PM (GMT -6)   
fathers son said...
...but very curious if anyone is familiar with any linkage between Lyme, PSA elevation of prostate disease?
Are you familiar with www.pubmed.govPubMed is a service of the US National Library of Medicine (National Institute of Health; your tax dollars effectively at work!).  It has online database that provides free access to MEDLINE records.  MEDLINE is a database of reports & studies from thousands of medical journals.  MEDLINE requires a subscription, but by using PubMed anyone can read the abstracts of reports, and can understand the main premise of the study, including the conclusion and results.
I went to the website and entered "prostate and lyme" into the Search function (and also "PSA and lyme"), and nothing of any consequence came up.  I would say that they are unrelated.
Try the website yourself, for your future reference.

fathers son
New Member

Date Joined Nov 2009
Total Posts : 8
   Posted 11/29/2009 8:11 PM (GMT -6)   
Thank you all...Casey great info

Regular Member

Date Joined Oct 2005
Total Posts : 489
   Posted 11/29/2009 8:56 PM (GMT -6)   

It is my personal opinion that PCa is associated with some form of long term intra-cellular bacterial inflammation. I am sure if prostate biopsies/post surgery samples were properly checked they would find colonies of bacteria in close proximity to the cancerous cells. (One cancer researcher who did have PCa did have his prostate examined for such bacteria and did find them and photos are on the Net.). But if you think you have Lyme, then that too is likely associated with similar systemic inflammation caused by similar intracellular bacteria. The most common way to check for this is to get your D's tested.
1,25 dihydroxyvitamin -D <<<< this will be elevated -- above 40 pg/ml
25 hydroxyvitamin - D <<<< this may be low (less than 15 ng/ml) but not always.

Just before I was diagnosed with PCa I had a 1,25D level of 48 -- which is really elevated.
(my 25,D was not really low tho -- around 30).

So, i suggest getting at least those two tested -- maybe CRp and ACE and SEDrate also.
(indicators of systemic inflammation).

Then you can take it from there.
Age 58, 195lbs, 6'4", 57 at DX, PSA Aug2008 7 4 ... June2007 4.7 (BPH + LUTS)
Biopsy Nov2008 1 of 12 cores 5%, Gleason 3+3 - Sona showed size 140+ cc (110 grams post op).
02/03/09 open RRP surgery , Nerve sparing both sides, 1 day in hospital, Day 4 first BM,
Pathology Report: All margins clear - No Invasive spread - no change in Gleason score.
02/18/09 Cath out, passed a 1cm oblong STONE within hours.
03/06/09 Started Levitra@20mg / Viagra@100mg / (04/01) Cialis@20mg -- no real effect (thru 11/2009).
04/01/09, 07/07/09, 10/01/09 PSA <0.1 - Stone Was Oxalate stone -- X-ray no stones.
08/09 - started MUSE@1000mcg ... pump&plump - success(80-90%) (alpro ache).
09/09 @500mcg +pump&plump + 2 advil - success(80-90%) - (less Alpro ache).
10/09 TrimixGel (500/300/100mcg): 1st:60%, 2nd:(pump&plump) 60%, 3rd(added 500mcg muse):70-80% -- (no Alpro aches!) but none @ useful hardness!

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