FDA approved clinical trial cyro-immunotherapy investigation info is available

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 12/18/2009 7:23 PM (GMT -6)   
Web info:  www.pioa.org
 
DR. Duke Bahn, MD prinicipal investigator can be reached at  888-234-0004 if looking into this.
An article written in Pacct Newsletter Page 5-6  62 yr old patient, underwent  some cryo and subsequent intraprostatic injection of over 2 million of his own live dendritic cells, the patients results have been excellent via comparison:  prior had difficulty walking, his MRI showed destructive bony lessions in his lumbar vertebrae and soft tissue (cancer) extending into the spinal canal had pressure on spinal cord (compression etc.). 
 
Now following treatment 6 weeks after, had lessening of pains, 3 weeks later stopped pain meds and took to walking up to 6 miles per day. Subsequent MRI showed improvement in bony lession in the lumbar vertebrae and spinal cord. The total article would need to be read, it is hopeful stuff. The future of immuno-therapy is something you might want to watch closer and especially if you are at high risk and failing all prior treatments.
 
Might be of use to somebody out there. (there is tab on his site to links on protocols..the one with words immunotherapy within is the article to read)


Youth is wasted on the Young-(W.C. Fields)

Post Edited (zufus) : 12/18/2009 8:00:02 PM (GMT-7)


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25364
   Posted 12/18/2009 7:59 PM (GMT -6)   
Very interesting, do you think this one patient was a fluke with the postive reaction, or could it be the start of a new treatment method?
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA:
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 in place


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 12/18/2009 8:18 PM (GMT -6)   
This is similar to Leukine useage and such that works on the cellular level with dendritic cells the results are there on using Leukine with or w/o other chemical agents for PCa combos.
It is not a fluke, it is more of a fluke that we don't know enough about this type of thing.
David these docs that are the pioneers are going to be the ones making this stuff a reality for our futures or of the face of PCa. There are patients using Leukine right now, it is not a hormone thing at all, it is basically without side effects it is said, but is costly cause it is patented. That can change sooner or later. Have one guy in our PCa group(12 yr. survivor) using Leukine with results right now, seeing Dr. Scholz(1-2 time per year-traveling) and gets to self administer the Leukine shot once a week at home. Luckily his insurance is paying this right now.  It is working against his HRPCa which is a delightful event for a patient who has run out of 'normal' treatments. The next questions is always 'how long', if you have limited time....long is relative and has different meanings to different people.
 
Peace be with you, Merry X-mas
 
 
 
Youth is wasted on the Young-(W.C. Fields)


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25364
   Posted 12/18/2009 8:25 PM (GMT -6)   
I have no problem with experimental drugs, and until they are in full production in sufficient quantities, obviously expensive. Many years ago, wife dealt with severe case of Hep C, this was before it was ever in the news. We had to sign special releases for the complex drug mixes they had her on. Now some of the same drugs are used as a standard procedure for Hep C. Had to give that poor woman a shot in her stomach every week for a year, got to where I could give a needle with no pain. BTW, total cure so far.

I am hoping that through research, much better tools will be there for the next generation of PC dx men. May or may not do us anygood, but would love to know that if either of my son's were to get it, they could have better choices and solutions.

Thank God for research.

David

PS I agree, how long is both subjective and relative.
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA:
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 in place


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 12/18/2009 9:12 PM (GMT -6)   
Exactly bro you want better therapies, better concepts and ideas to work? It is plenty of perspiration and inspiration and pioneers that get off their _sses that make it happen...they could have chosen x.y.z. to make a faster buck ...but maybe they have a higher calling..maybe making all the $$$$ you can is not all that fulfilling, personally you can be wealthy and starving from what matters in life. What is it worth to have Jonas Falk, Thomas Edison, Eli Whitney, Alex Graham Bell, Ben Franklin...et al...on earth???(beyond measure??) These are the heros.

Now do you love status quo on all cancers and diseases or would you like to move on???
I think based upon the status quo results the majority of patients, say find me a better mouse trap and way to go, I like being continent or having normal sex life and longevity. Hopefully the futures so bright we gotta wear shades.cool cool cool cool cool cool cool cool cool cool cool cool cool cool cool
Youth is wasted on the Young-(W.C. Fields)

Post Edited (zufus) : 12/18/2009 8:15:13 PM (GMT-7)


Ed C. (Old67)
Veteran Member


Date Joined Jan 2009
Total Posts : 2457
   Posted 12/18/2009 9:26 PM (GMT -6)   
Zufus,
Thanks for posting. It is always pleasing to hear about new drugs and treatments in the fight against PCa. Even if it doesn't help the current generation, it will help our children and grand children.
Age: 67 at Dx on 12/30/08
PSA 9/05 1.15; 8/06 1.45; 12/07 2.41; 8/08 3.9; 11/08 3.5 free PSA 11%
2 cores out of 12 were positive Gleason (4+4) and (4+5)
Negative CT scan and bone scan done on 1/16
Robotic surgery performed 2/9/09 Dr Fagin, Austin TX
Pathology report:
Prostate weighed 57 grams size:5.2 x 5.0 x 4.9 cm
Posterior lateral lesions measuring 1.5 x 1.4 x 1.0 cm showing focal capsular penetration over a distance of 3mm.
Prostatic adenocarciroma accounts for approx. 10-20% of the hemisphere.
Gleason 4+4
both nerve bundles removed,
pT3a Nx Mx, Negative margins
seminal vesicles clean, lymph nodes: not dissected
continent after 4 months
8 weeks PSA test 4/7/09 result <0.1
5 months PSA test 7/9/09 result <0.1
8 months PSA test 10/9/09 result <0.1

New Topic Post Reply Printable Version
Forum Information
Currently it is Sunday, April 22, 2018 3:55 PM (GMT -6)
There are a total of 2,954,337 posts in 324,108 threads.
View Active Threads


Who's Online
This forum has 162157 registered members. Please welcome our newest member, 19crowsnest.
294 Guest(s), 8 Registered Member(s) are currently online.  Details
19crowsnest, PeterDisAbelard., GoBucks, Cberg, Hoagie, Patulsius, straydog, PDXtransplant