I will be getting my sixth lupron shot next week. This will be month 20 for me on HT. The side effects that I have had related to the hormone therapy are as follows:
Loss of body hair. (legs, arms, chest, was already missing a good bit on my head so can't say that it has affected that)
Hot flashes. Initally quite uncomforatable and frequent. These days less frequent and not as long in duration.
Atrophy of testicles. Thought it was my imagination but doc says there can be some shrinkage here. Says it will come back when lupron is stopped.
Can't say that I had a lot of depression but I did have some brief moments of self pity. Like Tony, I try to stay optimistic and positive about all this.
Zero libido. Yesterday I was taking more notice of the women in the airport for the first time in months. My last shot must be wearing off.
I have had a modest weight gain. I keep up with my workouts but have slid a little on diet. More likely the diet is the cause.
I have had to cut back on the weight I was lifting. Just cannot seem to do as much so I do a few more sets. That may just be age too.
I do tire a bit more easily when doing strenuous work but luckily I am not called upon to do that too often.
All in all the side effects have not been too intolerable. As for anyone noticing.... do not worry about that. The only one that is even remotely noticable to others is the brief moisture on your face from the hot flashes.
On the radiation side.... been there done that. It was a piece of cake. Had a mild bout with diarrhea and urinary difficulty about half way through due to full pelvic treatments. Cleared up as soon as that was complete and had no further problems and none since that I can tie to the radiation. I do not have erections but then I do not have any desire either. I am single and live alone so this has not been as issue for me.
As you know each of us are different and our bodies have different tolerances to abuse. (for example Keith Richards ) Your experience may be better or worse.
Wishing you the best possible outcome.
Diagnosed 04/10/08 Age 58 at the time
Gleason 4 + 3
DRE palpable tumor on left side
100% of 12 cores positive for PCa range 35% to 85%
Bone scan clear and chest x ray clear
CT scan shows potential lymph node involvement in pelvic region
Started Casodex on May 2 and stopped on June 1, 2008
Lupron injection on May 15 and every four months for next two years
Started IMRT/IGRT on July 10, 2008. 45 treatments scheduled
First 25 to be full pelvic for a total dose of 45 Gray to lymph nodes.
Last 20 to prostate only. Total dose to prostate 81 Gray.
Completed IMRT/IGRT 09/11/08.
PSA 02/08 21.5 at diagnosis
PSA 07/08 .82 after 8 wks of hormones
PSA 10/08 .642 one month after completion of IMRT, 6 months hormone
PSA 03/09 .38 six months post radiation and nine months into hormones
PSA 06/09 .36 or .30 depending on who did the test
PSA 09/09 .33 one year after IMRT and 16 months into hormone