IMRT - 3 Years Out

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Paralleli
Regular Member


Date Joined Jul 2008
Total Posts : 123
   Posted 1/14/2010 5:04 PM (GMT -6)   
For those interested in IMRT:
 
IMRT as primary treatment in 1/07.
Urethral stricture in 10/07 treated successfully with dilation.
To date, no other side effects
@ 53 yrs PSA 4.8
T1c – Gleason 3 + 3
IMRT 1/07 thru 2/07 (42 treatments)
PSA 6/07 – 0.76
PSA 12/07 – 0.36
PSA 6/08 – 0.72
PSA 12/08 - 1.06
PSA 6/09 - 1.02
PSA 1/10 - 0.91


James C.
Veteran Member


Date Joined Aug 2007
Total Posts : 4462
   Posted 1/14/2010 5:06 PM (GMT -6)   
Seems as if your run of good stats has been extended. Congrats and thanks for sharing..
James C. Age 62
Co-Moderator- Prostate Cancer Forum
4/07 PSA 7.6, referred to Urologist, recheck 6.7
7/07 Biopsy: 3 of 16 PCa, 5% involved, left lobe, GS 3/3=6
9/07 Nerve sparing open RRP 110gms.- Path Report: GS 3+3=6 Stg. pT2c, 110gms, margins clear
24 mts: PSA's: .04 each test since surgery, ED Continues-Bimix .3ml PRN or Trimix .15ml PRN


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 1/14/2010 6:14 PM (GMT -6)   
Congrats and good luck to you, you are doing well so far
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 in place


John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4223
   Posted 1/14/2010 8:24 PM (GMT -6)   
Did you have any urinary issues immediately after radiation or did it just show up 8 months later?
JT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


Sonny3
Veteran Member


Date Joined Aug 2009
Total Posts : 2447
   Posted 1/14/2010 8:42 PM (GMT -6)   
Paralleli,

Thanks for sharing. As a guy completing my IMRT tomorrow after surgery 4 months ago, I sure hope to have your stats three years from now.

Thanks again for the encouraging post,

Sonny
61 years old
PSA 11/07 3.0
PSA 5/09 6.4
Diagnosis confirmed July 9, 2009
12 Needle Biopsy = 9 clear , 3 postive
<5%, 90%, 40%
Gleason Score (3+4) 7 in all positive cores
CT Organ Scan - negative
Nuclear Bone Scan - Negative
da Vinci 9/17/09
Post Surgery Pathology:
Gleason: Changed to (4+3) = 7
Stage: T3a
Tumor Volume 12.5%
NERVES SPARED-positive margin, extra-prostatic extension
30 day PSA 0.4, 50 day psa 0.53, 64 day psa 0.6
IMRT scheduled to begin Nov 30,2009 (74 days post surgery)


Paralleli
Regular Member


Date Joined Jul 2008
Total Posts : 123
   Posted 1/14/2010 9:24 PM (GMT -6)   
James C.:

Thanks. Seems that your run of good stats has been extended also.


Purgatory:

Yes, I am “doing well so far.......”. However, I tend to to think of it a just “doing well”. The present makes more sense to me. Thanks.

JT:

I had some frequency issues that started about six weeks into the eight-week course of treatments. Hytrin cleared those up, literally, almost overnight. The constriction that became apparent at 8 months was scarring caused by the radiation. I’ve got a good Uro and the dilation, followed by a course of self cath’ing to keep things open, did the job. The issue seems to have resolved itself. Best….
@ 53 yrs PSA 4.8
T1c – Gleason 3 + 3
IMRT 1/07 thru 2/07 (42 treatments)
PSA 6/07 – 0.76
PSA 12/07 – 0.36
PSA 6/08 – 0.72
PSA 12/08 - 1.06
PSA 6/09 - 1.02
PSA 1/10 - 0.91


Paralleli
Regular Member


Date Joined Jul 2008
Total Posts : 123
   Posted 1/14/2010 9:30 PM (GMT -6)   
Sonny:

I think I read that you were having some urinary impacts from the IMRT. If you haven't talked with the Doc's about it, do. The Hytrin did wonders for me, and it is CHEAP.

Best....
@ 53 yrs PSA 4.8
T1c – Gleason 3 + 3
IMRT 1/07 thru 2/07 (42 treatments)
PSA 6/07 – 0.76
PSA 12/07 – 0.36
PSA 6/08 – 0.72
PSA 12/08 - 1.06
PSA 6/09 - 1.02
PSA 1/10 - 0.91


don826
Veteran Member


Date Joined May 2008
Total Posts : 1010
   Posted 1/16/2010 7:47 AM (GMT -6)   
Hi Paralleli,

Thanks for posting. I too had IMRT as a primary treatment and I am in my second year. So far so good and no side effects to speak of.

Best to you.
Don
Diagnosed 04/10/08 Age 58 at the time
Gleason 4 + 3
DRE palpable tumor on left side
100% of 12 cores positive for PCa range 35% to 85%
Bone scan clear and chest x ray clear
CT scan shows potential lymph node involvement in pelvic region
Started Casodex on May 2 and stopped on June 1, 2008
Lupron injection on May 15 and every four months for next two years
Started IMRT/IGRT on July 10, 2008. 45 treatments scheduled
First 25 to be full pelvic for a total dose of 45 Gray to lymph nodes.
Last 20 to prostate only. Total dose to prostate 81 Gray.
Completed IMRT/IGRT 09/11/08.
PSA 02/08 21.5 at diagnosis
PSA 07/08 .82 after 8 wks of hormones
PSA 10/08 .642 one month after completion of IMRT, 6 months hormone
PSA 03/09 .38 six months post radiation and nine months into hormones 
PSA 06/09 .36 or .30 depending on who did the test
PSA 09/09 .33 one year after IMRT and 16 months into hormone
 
 
 

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