PSA Results Can Make You Crazy

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SubicSquid
Regular Member


Date Joined Oct 2009
Total Posts : 252
   Posted 1/23/2010 1:29 PM (GMT -6)   
My 30 day PSA was .07 (ultra sensitive test). I was waiting for my 90 day and got it over the phone from my Primary Care Doctor who said it was .15. That indicated a doubling of the PSA. Saw my urologist yesterday and when he asked how I was, I said the doubling PSA was not good.He responded with "what are you talking about - your PSA is fine - <0.15 (standard PSA test), which is how the lab in my hospital reports rather than <0.1. Needless to say, I worried about nothing. I will see the radiology oncologist on February 2nd. I feel that he will try and talk me into IMRT, which he was urging during the first visit, but I think I will delay it until I get my next PSA in 90 days. My urologist concurs. My radiology oncologist is of the same opinion as Sonny's - IMRT should be done as soon as possible after surgery for the best results. But, I feel why get it if I don't really need it. I think I will try and not sweat out my PSA results as much.
Age 63, PSA July 2009 5.66
Diagnosed July 2009, Biopsy: 2 of 12 cores positive, Gleason 3 + 5 = 8

MRI and Bone Scan Negative.

open Surgey October 22, 2009 (6 hours on table; 2 units blood)

Small part of incision infected (2 staples removed); finally healed at 3 month mark.

Prostate, both nerve bundles, seminal vessels, and two lymph nodes removed during surgery.

Post surgery Biopsy, Gleason 4 + 3; 2 positive margins


Returned to work after 6 weeks. First week worked only half days because of pain from sitting for long periods.

Still slightly incontinant after 12 weeks - 1 pads per day (light). Dry at night. 1-2 trips to toilet.

ED - Yes (will start Levitra possibly in January)

30 day PSA (ultra-sensitive) .07

90 day PSA (standard) <.15


livinadream
Veteran Member


Date Joined Apr 2008
Total Posts : 1382
   Posted 1/23/2010 1:33 PM (GMT -6)   
I would not be overly concerned at this point. Wait for a couple more test and look at the trend. I do however agree that it can drive you crazy.

peace and joy
Dale
My PSA at diagnosis was 16.3
age 47 (current)

http://www.caringbridge.org/visit/dalechildress

My gleason score from prostate was 4+5=9 and from the lymph nodes (3 positive) was 4+4=8
I had 44 IMRT's
Casodex
Currently on Lupron
I go to The Cancer Treatment Center of America
Married with two kids
latest PSA 5-27-08 0.11

PSA July 24th, 2008 is 0.04
PSA Dec 16th, 2008 is .016
PSA Mar 30th, 2009 is .02
PSA July 28th 2009 is .01
PSA OCt 15th 2009 is .11
PSA Jan 15th 2010 is .13

Testosterone keeps rising, the current number is 156, up from 57 in May

T level dropped to 37 Mar 30th, 2009
cancer in 4 of 6 cores
92%
80%
37%
28%


BillyMac
Veteran Member


Date Joined Feb 2008
Total Posts : 1858
   Posted 1/23/2010 5:55 PM (GMT -6)   
Certainly PSA tests and the way they are reported can drive you crazy. I am at a loss as to why doctors, of all people, and especially when dealing with PCa do not see or understand the special significance of the < sign in front of the number. There is a world of difference with a patient (who was .05) having a new PSA report that says <0.1 and the doc telling him "your PSA is 0.1". The new report indicates no change while the doc is essentially saying PSA has doubled. The figure <0.15 is an unusual way of reporting the PSA..........I don't believe I have ever seen it expressed quite that way.............plenty of <0.1s but usually if it is above 0.1 there is a definite figure such as 0.15, 0.2 etc. it might be worthwhile getting clarification and make sure you get and keep your own copies of reports.
Best wishes for continued good health,
Bill
1/05 PSA----2.9 3/06-----3.2 3/07-------4.1 5/07------3.9 All negative DREs
Aged 59 when diagnosed
Biopsy 6/07
4 of 10 cores positive for Adenocarcinoma-------bummer!
Core 1 <5%, core 2----50%, core 3----60%, core 4----50%
Biopsy Pathologist's comment:
Gleason 4+3=7 (80% grade 4) Stage T2c
Neither extracapsular nor perineural invasion is identified
CT scan and Bone scan show no evidence of metastases
Da Vinci RP Aug 10th 2007
Post-op pathology:
Positive for perineural invasion and 1 small focal extension
Negative at surgical margins, negative node and negative vesicle involvement
Some 4+4=8 identified ........upgraded to Gleason 8
PSA Oct 07 <0.1 undetectable
PSA Jan 08 <0.1 undetectable
PSA April 08 <0.001 undetectable (disregarded due to lab "misreporting")
PSA August 08 <0.001 undetectable (disregarded due to lab "misreporting")
Post-op pathology rechecked by new lab:
Gleason downgraded to 4+3=7
Focal extension comprised of grade 3 cells
PSA September 08 <0.01 (new lab)
PSA February 09 <0.01
PSA August 09 (2 year mark), <0.01
PSA December 09 <0.01

My Journey: www.yananow.net/Mentors/BillM2.htm


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 1/23/2010 7:02 PM (GMT -6)   
Subic, surprised you would be getting pushed for RT or SRT this soon. You still haven't met the basic criteria for recurrance. I would wait for at least one, if not two more PSA tests spread over the next 3 to 6 months, to see if you get 3 consecutive rises above .10. And it would be in your best interest for peace of mind, to use the same lab, so that you are doing apples to apples.

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/10 - Corrective Surgery #4, and Caths #11 and #12 in at the same time

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