biopsy results interpretation would be appreciated............

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hightimes
New Member


Date Joined Dec 2009
Total Posts : 7
   Posted 1/25/2010 2:33 PM (GMT -6)   
Tlc Gleason 7 adenocarcinoma of the prostate



PSA 4.6. TRUS/bx cores - evaluate for malignancy



Right lateral apex received in formalin is a 1.3 cm tan core (1ns)



Right medial apex received in formalin is a a 1.3 cm tan core (1ns)



Right anterior (right lateral mid) received in formalin is a 1.4 cm tan cor (1ns)



Right medial mid received in formalin is 1.o cm tan core (1ns)



Right lateral base received in formalin are two tan cores 0.2 to 1.2 cm (2ns)



Right medial base received in formalin is a 1.2 cm tan core (1ns)



Left lateral apex received in formalin is a 1.2 cm tan core (1ns)



Left medial apex received in formalin is a 1.1 cm tan core. (1ns)



Left anterior (left lateral mid) Received in formalin is a 1.2 cm tan core. (1ns)



Left medial mid received in formalin is a 1.2 cm tan core. (1ns)



Left lateral base received in formalin is a 1.2 cm tan core. (1ns)


Left medial base received in formalin are two tan cores 0.1 to 1.2 cm. (2ns)

Microscopic:

Prostate Core Biopsy

Site positive carcinoma volume Gleason(1) Gleason(2) Gleason(3) Gleason PNI

% of individual

Core %

R lat 1/1 <10% <10% 3/50 6 No

Apex

1

R med

Apex 1/1 <5% <5% 3/50 3/50 6 No

R ant

Horn 1/1 20% 20% 3/70 4/30 7 No

3

R med

Mid 1/1 >90% >90% 3/70 4/30 7 Yes

4

R let

Base 1/1 >90% >90% 3/90 4/10 7 Yes

5

R med

Base 1/1 10% 10% 3/90 4/10 7 No

6

Microscopic Diagnosis :

1-6 Prostate, right lateral apex, right medial apex, right anterior horn, right medial mid, right lateral base and right medial base, needle biopsies

Prostatic adenocarcinoma, combined Gleason score 3 + 4 = 7. Perineural invasion present

7-12 Prostate, see sites above, needle biopsies: benign prostatic parenchyma, negative for neoplasm


posted partial results last week and here is the full report. thanks in advance for any and all replies.

sean/amin......................

Casey59
Veteran Member


Date Joined Sep 2009
Total Posts : 3172
   Posted 1/25/2010 2:52 PM (GMT -6)   

Sean & Amin,

There is a lot to learn, but here’s some basics from the data you provided.

The biopsy has confirmed that presence of prostate cancer, and has assigned a “Gleason score” of 3+4=7.  High-level viewpoint, Gleason score of 7 is moderately aggressive, but as you may learn later if you dive into more details, 3+4 more favorable than 4+3…too much detail for now.

Almost all patients today present with a Gleason score of 6 or 7.  With the information you provided, this cancer is likely to be very treatable through one or more alternative methods.

Amin’s father’s urologist has probably started explaining the alternatives to him, because ultimately he will need to make some sort of decision on what to do.  While most prostate cancers tend to be slow growing, this should not be ignored for long. 

There is lots of reading material available online.  The Prostate Cancer Research Institute has a website is a great starting point.  Here’s the link to the “Newly Diagnosed” section:  http://www.prostate-cancer.org/pcricms/node/19

Hope that this reply helps you down the path…


hightimes
New Member


Date Joined Dec 2009
Total Posts : 7
   Posted 1/25/2010 3:10 PM (GMT -6)   
Casey.........

thanks for the understandable reply. now its time for amin to start doing some research. The doctors gave his father a choice. Start with radiation or go straight to surgery. he chose the prior and will begin radiation treatment Feb.25. i think its a 6 week treatment but that is a guess. Amin is so concerned about all of this and his father doesnt like anyone to know or say anything concerning his health. Very private kind of a guy. this really helps. thanks again casey.

Casey59
Veteran Member


Date Joined Sep 2009
Total Posts : 3172
   Posted 1/25/2010 3:33 PM (GMT -6)   
Glad to help.
 
After reading through the PCRI's "Newly Diagnosed" section, navigate to the section on "Local Therapies."  When there, look for Intensity Modulated Radiation Therapy (IMRT)...this is the 6-week treatment his urologist has recommended.  At the "Local Therapies" page, there is one high-level overview link, and one more detailed article.
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