Slides showing each of the Gleason types

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RickyD
Regular Member


Date Joined Dec 2009
Total Posts : 163
   Posted 2/3/2010 1:43 AM (GMT -6)   
A good source if you want to see what these slides resemble.
 
http://webpathology.com/case.asp?case=20
Age 55,  PSA = 4.97 on 11/17/09, DRE negative,
Biopsy 12/2/09: 1 of 12 cores positive with less than 5% volume
Gleason 3 + 3 = 6
Prostate Size Estimate on 12/2/09 = 28 cc


English Alf
Veteran Member


Date Joined Oct 2009
Total Posts : 2218
   Posted 2/3/2010 4:33 AM (GMT -6)   
Ricky

These are obviously interesting and informative images for experts, but I'm not exactly sure if they can tell us, as patients, very much.

I wouldn't want anybody to think that they could play amateur pathologist and get hold of their own slides to compare them with this set and then think they can work out their own Gleason score for themselves. (I had enough trouble at university working out what I was looking at under a microscope when it was my own subject I was dealing with!)

What I think would be much better would be if our urologists hadn't given us our biopsy or post-op results, but if the actual pathologist had done the explaining and shown us our own slides and told us what all the different shaped blobs were and explained how they had calcualted our Gleason scores. (The pathologist doesn't explain the surgery, so how come the surgeon explains the pathology?!)

Alfred

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 2/3/2010 10:18 AM (GMT -6)   
Good point, Alfred, never thought of that way before.
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/10 - Corrective Surgery #4, and Caths #11 and #12 in at the same time


Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3743
   Posted 2/3/2010 11:27 AM (GMT -6)   
Great site. Thanks. One picture is worth 100 owrds and there are many pictures. Now I understand why some people here are read 4+3 or 3+4 or 3+3. A lot of subjectivity is required.
These photos sure beat the black and white drawings I have seen before.
Jeff

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 2/3/2010 12:17 PM (GMT -6)   
Well, I would rather not look at the slides, especially if they were mine. There is a subjective factor big time in how to interpet the slides, but the big difference, if some one untrained like myself (or most anyone here at HW) were looking at them, we would be reading all kinds of things into them. Not the same kind of subjectivity that a professional pathologist with lots of experience would have when looking at the same slides. Plus, we, would have a bias to read something good or something bad into our own slides, depending on what frame of mind we were in at the time. The pathology people, we are just another blind slide to them, no vest interest either way.

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/10 - Corrective Surgery #4, and Caths #11 and #12 in at the same time

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