2 different path reports

New Topic Post Reply Printable Version
37 posts in this thread.
Viewing Page :
 1  2 
[ << Previous Thread | Next Thread >> ]

worried-wife
New Member


Date Joined Feb 2010
Total Posts : 14
   Posted 2/3/2010 8:31 PM (GMT -6)   
 
 
Hello,
 
Looking for some information on what to take from the 2 different path reports.  My husband had a biopsy in Jan and was told by the urologist that his results were suspicious and he wants to do another biopsy in 3 months from last biopsy.  When asked what that meant he stated that 1 lab stated that it did not look like cancer but did not look normal (few atypical cells) was noted and the other lab stated it was a very small foci of cancer with high grade pin (1 core of 12 cores) stated it was less than 1mm.   My husband called a few days later after taking this all in and asked the uro if he should get a another path to read the biopsy, the uro told him that it was necessary since it went to John Hopkins.   So we are wondering why would we want a second biopsy if Hopkins stated cancer?
 
We spoke with our primary doc and he was fine with the uro decision but did say it does not hurt to get another opinion.  So we will be seeing a doctor on March. 
 
My husband will be 54 next month and is very active.  Last psa was 6.8 which went up from his last.  He has been seeing the uro for 2 years to monitor his psa.  
 
Thanks!

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 2/3/2010 9:21 PM (GMT -6)   
Hello and welcome,

Would definitely get still another opinion, too important not too. Please keep us posted.

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/10 - Corrective Surgery #4, and Caths #11 and #12 in at the same time


IdahoSurvivor
Veteran Member


Date Joined Aug 2007
Total Posts : 1015
   Posted 2/3/2010 10:03 PM (GMT -6)   
Hello worried,

Welcome to a great place to discuss your concerns and talk to many "birds of a feather."

I agree with Purgatory that more testing is necessary to ensure you have all the information needed.

It is very hard not to worry, yet if there is a further concern, you and hubby are doing what is necessary to address it early.

All the best,

Barry
Surgery: Da Vinci; July 31, 2007; 54 on surgery day;
Pathology: PSA: 4.3; Gleason: 3+3=6; T2a; Confined to Prostate;
Post RP PSAs: 09/07 <0.04; 12/07 <0.04; 03/08 <0.04;
06/08 <0.04; 12/08 <0.04; 06/09 =0.06; 09/09 <0.04;
Latest PSA 12/09 =0.05


142
Forum Moderator


Date Joined Jan 2010
Total Posts : 6945
   Posted 2/3/2010 10:32 PM (GMT -6)   
I agree that another opinion may at least settle the waters a bit. I am 56, and in July had a 7.4 PSA, but a really bad biopsy report (9 positive of 12, Gleason 4+3), so off to DaVinci. His numbers are infinitely better than mine, but careful attention at 54 might have given me more options. I can't look back now, but being 2 years further down the road, my advice is - do a better job than I did.

John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4223
   Posted 2/4/2010 12:13 AM (GMT -6)   
Worried wife,
What seems to have been found is what 50% of men your husband's age have, indolant cancer culsters or high grade PIN. It's really nothing to be worried about, but just the word Cancer sets off a lot of fear.
This is a situation that needs watching, another biopsy in 6 months is a good idea, so are regular psa tests. Based on the biopsy results it is certainly nothing that warrents treatment at this stage.
JohnT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


worried-wife
New Member


Date Joined Feb 2010
Total Posts : 14
   Posted 2/4/2010 7:16 AM (GMT -6)   
Thanks to all, we are seeing a doctor (Dr. Wein) on March 11th at HUP here in Philly. We just need to have confirmation of what is the right thing to do here. I have been doing alot a research it seems that there needs to be some improvement for men with this type of situation.

Will keep you posted.

Thanks Again,
Angela

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 2/4/2010 8:51 AM (GMT -6)   
Will keep you guys in our thoughts and prayers, Angela. Please report back when you have the meeting.
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/10 - Corrective Surgery #4, and Caths #11 and #12 in at the same time


worried-wife
New Member


Date Joined Feb 2010
Total Posts : 14
   Posted 3/5/2010 10:55 AM (GMT -6)   
Just returned from our appt with Dr. Wein at HUP and he's suggestion is to have an MRI then another PSA test before seeing him again on April 8th. They will be reviewing the biopsy slides also. He gave 2 options to my husband which is AS or surgery. Of course AS would only be if the MRI does not show more or a rise in the PSA. Did not recommend radiation since my husband is 53 which he felt surgery was the better option.

He does not do robotic and has his opinions of why it is not as good as the old fashion way.

So wanted to update everyone.

John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4223
   Posted 3/5/2010 11:25 AM (GMT -6)   
Worried wife,
If any doctor tells you there is one best way to treat this disease and gives you only two options then run for the hills as he is not giving you the straight scoop.

In low grade contained PC, every treatment option results in the exact same result, a cure rate in the mid to high 90% and a long term survival. open surgery, robotic surgery, Brachytherapy, IMRT, Proton, Cryosurgery and HIFU all are valid treatments as well as AS. The doctor you choose will have more affect than the treatment you choose.

Please do as much research as possible and get multiple opinions from docors in different fields, such as surgery, brachy and IMRT. Even see a doctor that specializes in AS as this is the alternative that will have the least affect on your life. Read the posts on this board, the vast majority of them are about how to deal with the after affects of treatment. Study the side affects of each treatment as in all probability this is what you will have to deal with, as cure rates for all treatments are extreamely high. Talk to patients that have had each treatment and ask them about their recovery time and side affects.
JohnT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 3/5/2010 11:47 AM (GMT -6)   
Worried,

I think you need to find another doctor in a big way. If that was the doctor's answer and attitude, then I agree with John above, find a new doctor. With what you posted so far on your husband's situation, he should have all options available to him, and there doesn't seem to be any time pressure to make a quick decision that may be regretted later on. It's even highly unlikely that an expensive MRI test is going to remotely show anything connected to PC at this point.

Definitely time for a sound second opinion and accessment of his situation. Good luck.

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12  same time, 2/8-Cath #11 out - 21 days, 3/2- Cath #12 out - 41 days, 3/2- Corr Surgery #5, Caths #13 & #14 same time


142
Forum Moderator


Date Joined Jan 2010
Total Posts : 6945
   Posted 3/5/2010 11:55 AM (GMT -6)   
You should always get an opinion from a radiation oncologist. I was sent directly to one from my urologist's office. I didn't like anything the radiation oncologist told me, but I was able to make my own decision that it was not the path for me. I'm sure the Urologist knew what I would hear and what I would decide, but he required me to hear the radiation story before we would talk again.

worried-wife
New Member


Date Joined Feb 2010
Total Posts : 14
   Posted 3/5/2010 11:55 AM (GMT -6)   
Thanks for the responses. The funny thing is that this was a second opinion as the first uro said to wait for another biospy. This doctor we saw today is suppose to be one of the best in the area and was even told in the world. I just got the feeling that he is a surgeon that is what he feels is right. He did mention that he would have us speak with a radiation oncologist but his opinion is that surgery has a better cure rate. He was comfortable with AS as long as the PSA comes down to what it was before the spike.

I told my husband that he should still look into the other options especially since seeds was what he thought he would do first. Does anyone know about cryo for prostate? Where only the effected area is treated?

Thanks,
Angela

tatt2man
Veteran Member


Date Joined Jan 2010
Total Posts : 2842
   Posted 3/5/2010 12:18 PM (GMT -6)   
Angela:

I understand the run-like-hell response from some of the other posters, since your doctor was recommending open radical prostatectomy over robotic, etc.
Mind you, he was stating what he is best at and he knows his success rate of his patients.

The type of operation - surgery -open or robotic, AS, radiation, etc.. would be decided BY you, your husband, the doctor and other specialists in their select fields - with all the successes and pitfalls that can occur.
Once that is decided, then you can decide on the doctor.

A good deal of recovery is knowing in your heart you chose the best way to deal with the prostate cancer AND the best doctor for you (your husband).

In my situation, I was given one option - one surgeon - I asked all my questions - got my answers and then asked even more questions.
I delayed the operation until I was ready to "cross over" - I have had my ups and down since the operation - but content ( a key word) in my choices.

Wishing you and your husband all the love and support this group here at HW and your friends and family can muster.
Hugs.
BRONSON
.................
Age: 54 - gay - with spouse, Steve - 59
PSA: 04/2007- 1.68 - 08/2009 - 3.46 - 10/2009 - 3.86
Confirmation of Prostate Cancer: October 16, 2009 - 6 of 12 cancerous samples , Gleason 7 (4+3)
Doctor: Dr. Mohamed Elharram -Urologist / Surgeon - Peterborough Regional Health Centre
Radical Prostatectomy Operation: November 18, 2009 , home - November 21, 2009
Post Surgery Biopsy: pT3a- gleason 7 - extraprostatic extension - perineural invasion - prostate weight - 34.1gm -
ED Prescription: Jan 8/2010 - started daily 5mg cialis - girth back to normal -but not much length - will go for trimix in April when I see doc
Incontinence: 3-5 pads/1-2 clothes changes/day- finally seeing improvement - March 3, 2010 - week 14 after surgery -
location: Peteborough, Ontario, Canada
Post Surgery-PSA: to be announced - April 8, 2010
............


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 3/5/2010 8:54 PM (GMT -6)   
MRI is probably worthless test (especially)if you only have HG-PIN and usually worthless on alot of even higher parameters, it is a money maker for the hospitals and such. I had clear scans with much higher stats than average patients(urinary total blockage)- and plenty of PCa 12/12 biopsies all 75-95% in each one, psa 46.6, Gleasons 7,8,9's found (2-sets of them about identical too). Does clear scans mean no PCa?....no they don't, they can only detect so small like 1-billion cells or such, so if clear, yes is good to hear but doesn't mean it is in stone and definitive,  this is the ugly truth about PCa..no scan especially in the USA right now is that super accurate. Dr. Strum leading reknown PCa oncologist/specialist writes in his book(A Primer on Prostate Cancer) and papers about the wasted money alot of docs are doing on scanning low level disease patients..as it finds nothing and thousands of dollars wasted, better spent on other tests and things. You are not going to like the world of PCa, exceptions, non-definitives, conflicting opinions and such is just the beginning of the jungle...then comes treatments-side effects-monitoring etc.  Learn all you can is in your better interests, use your street smarts for listening to what you are told and varify everything is worth your time, get to know what is the truth of the matter. The Scans thing right away is a clue to look somewhere else, I smell bias, agenda and money spent for nothing, harsh aren't I...also witnessed and seen over the years, enough of cases of railroading patients w/o benefit of advising 2nd opinions(etc.), bad advise from some docs and errors-mistakes made even by my own uro-doc, whom got fired eventually. So, I am harsh for reasonable reasons and not unwarranted and I share this so other realize we are more like in the Twilight Zone, than you may think. There also are some fabulous docs, so how easy is it to pin-point them????

You did not say whom did pathology, you could have your slides sent to Bostwick, OppenHeimer, Epstein as they are the masters of expert pathology. Contact them and arrange their opinion on slides you have.
www.prostatelab.com (Oppenheimer)
www.bostwicklaboratories.com (Bostwick)
Google for Epstein

Dx-2002 March-April   (stats above-been one he__ of journey and still is)


Youth is wasted on the Young-(W.C. Fields)

Post Edited (zufus) : 3/5/2010 8:16:01 PM (GMT-7)


worried-wife
New Member


Date Joined Feb 2010
Total Posts : 14
   Posted 3/6/2010 7:48 AM (GMT -6)   
The pathology was first done by a commercial which the first uro uses which CBL path which they reported 1 core suspicious ASAP they then sent the one core to Hopkins who came back with Small foci of cancer less than 1mm with hgpin attached.

The doctor said the MRI can show if something is actually bigger than the 1mm. Is that true? I asked about the Color Doppler but he felt this was better.

I feel like PC is like a gambling world!

JoeFL
Regular Member


Date Joined Oct 2009
Total Posts : 420
   Posted 3/6/2010 8:14 AM (GMT -6)   
Angela,
 
For what it's worth.....
 
My urogogist did a good job of encouraging me to explore all the options....with one exception. He does not have a high opinion of Cryo. Doesn't mean that it does not work...just find out as much as you can.
 
Joe

Age -67 PSA - 4.5

Biopsy  (9/4/09) - Positive in 5 of 8 cores. In those 5 cores, 5 of 11 samples were positive. Gleason 3+3=6. Stage – T1C  Ct and Bone scans negative.

 

BT performed on 12/11/09. 84 seeds of Palladium 103. Surgery at 7:30 - Home at 12:30 same day with no catheter. Blood in urine for a week. Side effects as expected -  some burning, frequency, urgency.   Resumed daily  1 ½ mile walk after 3 days. Side effects have subsided some in the last week.

 

BT followed with 25 IGRT treatments beginning Feb 15 (4500 Gy's). 

 


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 3/6/2010 9:20 AM (GMT -6)   
Do you have the actual copies of the pathology reports, if not get them yours by law. If it went to Hopkins, did Epstein do the pathology and if so good, he is a reliable expert on pathology, in case you didn't know and you can still have it review by Bostwick or others if one wished such. Correct about the scans and in your case looks like a waste of time and money. Go get second opinions from like an oncologist and especially a PCa oncologist is in your BEST interests, not the docs be$t interests. E-d-u-c-a-t-i-o-n is your empowerment to know what is: Bull and Full in the glass.

www.prostate-help.org
www.yananow.net
www.ustoo.org
www.hypertext.org


Youth is wasted on the Young-(W.C. Fields)


worried-wife
New Member


Date Joined Feb 2010
Total Posts : 14
   Posted 3/6/2010 9:26 AM (GMT -6)   
Yes, we do have the path report from both labs (CBL and Hopkins). Epstein did the path also. It will now be reviewed by University of Pennsylvania path team as the Dr. Wein is there.

Thanks for the information and will continue to do our research.

Sleepless09
Veteran Member


Date Joined Jul 2009
Total Posts : 1267
   Posted 3/6/2010 10:26 AM (GMT -6)   
Hi Angela, sorry we have to meet like this, but welcome. As you've discovered this is a great place for advice and guidance through the murky waters of PCa.

Sounds like you're doing all the right things.

I hope you'll keep checking in and posting updates.

Sheldon AKA Sleepless
Age 67 in Apil '09 at news of 4 of 12 cores positive T2B and Gleason 3 + 3 and 5% to 25% PSA 1.5
Re-read of slides in June said Gleason 3 + 4 same four cores 5% to 15%
June 29 daVinci prostatectomy, Dr. Eric Estey, at Royal Alexandra Hospital Edmonton one night stay
From "knock out" to wake up in recovery less than two hours.  Actual surgery 70 minutes
Flew home to Winnipeg on July 3 after 5 nights in Ramada Inn  ---  perfect recovery spot!
Catheter out July 9
Final pathology is 3 + 4 Gleason 7, clear margins, clear nodes, T2C, sugeron says report is "excellent"
First post op PSA Sept 09  less than 0.02
PSA on Oct 23 test again less than 0.02
PSA on Jan 8 less than 0.02  
Oct 1st 09 -- dry at night, during day some stress issues.
Oct 31st padless 24/7 
Feel free to email me at:  sheldonprostate@yahoo.com    


worried-wife
New Member


Date Joined Feb 2010
Total Posts : 14
   Posted 4/11/2010 8:51 AM (GMT -6)   
Ok, we met with the doctor from HUP and the path team agreed with Hopkins path report.  My husband  has to go for a bone scan then make decision.  It's just crazy that something that measure .5mm can change your whole life.  We are just trying to make the right decison.  The doctor told my husband to take a few days to think what he whats to do AS or treatment. 

 
Age 54,  PSA = 6.8 on 12/09, DRE negative
Biopsy 1/10: 1 of 12 cores positive - cancer involvement .5mm - 5%
Gleason 3 + 3 = 6
 
 


ChrisR
Veteran Member


Date Joined Apr 2008
Total Posts : 825
   Posted 4/11/2010 10:01 AM (GMT -6)   
If his PSA is under 10 and he is Gleason 6 a bone scan is a waste of money. Johns Hopkins will not even do one with your stats. It is excess radiation you don't need. If u have RP from J. H. and stay Gleason 6 organ confined your chance of cure is 99.6%. Go to J. H. if you can.
Dx 42
Gleason 6 (tertiary score 0)
OPEN RP 10/08  Johns Hopkins
pT2 Organ confined Gleason 6
PSA Undetectable as of 10/15/09
Next PSA 10/15/2010


worried-wife
New Member


Date Joined Feb 2010
Total Posts : 14
   Posted 4/11/2010 12:04 PM (GMT -6)   
Chris...thanks for the info.
 
Age 54,  PSA = 6.8 on 12/09, DRE negative
Biopsy 1/10: 1 of 12 cores positive - cancer involvement .5mm - 5%
Gleason 3 + 3 = 6
 
 


John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4223
   Posted 4/11/2010 5:48 PM (GMT -6)   
Hopkins also has a good As program and you should talk to the head of the AS program before you make any decision. You have plenty of time so don't feel rushed. It's not reasonable for a doctor to tell you you have a few days to make a decision. You have years.

JT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


worried-wife
New Member


Date Joined Feb 2010
Total Posts : 14
   Posted 4/11/2010 5:53 PM (GMT -6)   
John,

We wondering if he offered AS as an option then why did he tell us that if we choose surgery then we need to schedule within the next 3 months.

Ang
 
Age 54,  PSA = 6.8 on 12/09, DRE negative
Biopsy 1/10: 1 of 12 cores positive - cancer involvement .5mm - 5%
Gleason 3 + 3 = 6
 
 


ChrisR
Veteran Member


Date Joined Apr 2008
Total Posts : 825
   Posted 4/11/2010 6:22 PM (GMT -6)   
Read this article. I went to J. H. Because if I stayed G6 organ confined I knew what my future would be. J. H. Not one patient has died of G6 cancer that they have treated. It is worth the trip if you can get there. Call them and ask to see Dr. Partin for a consult. Then I would have him do open RP. He was one of the surgeons that participated in the study below so you know how you will do if you stay organ confined G6. My surgery was 58 min. I was out of the hospital in one day. It could not have gone better. If other institutions have as good a cure rate for G6 organ confined I don't see them publishing it. That's why I went to J. H. Nobody else could show me what to expect.


http://prostatecancerinfolink.net/2009/09/22/surgical-outcomes-for-patients-with-organ-confined-gleason-6-prostate-cancer/
Dx 42
Gleason 6 (tertiary score 0)
OPEN RP 10/08  Johns Hopkins
pT2 Organ confined Gleason 6
PSA Undetectable as of 10/15/09
Next PSA 10/15/2010

New Topic Post Reply Printable Version
37 posts in this thread.
Viewing Page :
 1  2 
Forum Information
Currently it is Monday, June 18, 2018 9:50 AM (GMT -6)
There are a total of 2,972,780 posts in 326,010 threads.
View Active Threads


Who's Online
This forum has 160853 registered members. Please welcome our newest member, afayth.
450 Guest(s), 8 Registered Member(s) are currently online.  Details
hope abounds, GoBucks, tickbite666, 142, Redwing57, songlady, quincy, NotQuiteAntonio