From Dr. Catalona's Urological Research Foundation, www.drcatalona.com
Under the FAQ category, "Biopsy, Digital Rectal Exam, & Gleason Score, the following question was asked.
Q. TOO MANY BIOPSIES? Are there any negatives to having numerous prostate biopsy procedures?
A. Too many biopsy procedures can cause scarring around the prostate gland that can make nerve-sparing surgery more difficult.
I remember reading this a few months ago, and it caused me to think twice about
active surveillance with repetitive prostate biopsies.
1996, Age 48, Stage III Colon Ca, Colon Resection followed by 18 chemo treatments.
2000, Colon Ca Metastasis to upper left lung lobe. Lung lobe surgically removed. 24 chemo treatments scheduled. Took 1, declined the rest.
9/08 PSA is 2.8, 12/08 PSA is 4.56?? Chalk it up to prostatitis due to urinary retention after Nissen Fundo Surgery. VA docs prescribe 30 days of Septra. Prostate feels normal. PSA hovers around 4.1. VA docs want prostate biopsy but can't seem to get me into the schedule. Continue through Spring and Fall of 2009 thinking I have prostatitis. Bacteria cultures are always neg. PSA drops to 3.1 10/09.
12/09 Prostate Biopsy performed
3 of 10 cores positive, 5%, 25%, & 35%, 3 + 3= Gleason Six with perineural invasion.
Doc wants CT Scan due to prior Colon Ca. Findings: "The seminal vesicles are irregular & there is nodularity in the periprostatic fat such that local extension cannot be excluded. Shotty lymph nodes in both groin measuring 2.3 cm."
Doc wants Endo-rectal MRI (OUCH!) Findings: Mild central zone BPH, no discrete focus of carcinoma is identified, no evidience of invasion into the periprostatic fat or seminal vesicles. Normal size iliac chain lymph nodes.
2/08/10 Open RP surgery. Findings: Gleason Six upgraded to Seven. 3 + 4, Stage pT2c, Bilateral w/perineural invasion, No pos lymph nodes, margins uninvolved, no extraprostatic extension, no seminal vesicle extension, 39 grams, blood loss 1200 ml (didn't want a transfusion & didn't get one) nerve bundles spared bilaterally. current age-61