surgical margins vernacular

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Herophilus
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Date Joined Sep 2009
Total Posts : 664
   Posted 3/13/2010 8:41 AM (GMT -6)   

I have spent the last week reading about surgical margins. I have a suggested listed of new abbreviations for this topic.

BCF... Biochemical Failure

DFS... Disease Fee State

EPM... Extensively Positive Margin

FPM... Focally Positive Margin

NM... Negative Margin

PSM...Positive surgical Margin

Hero


Age 51, PSA 08/31/2009= 6.8, DRE Neg.
Biopsy 9/24/09 =10 of 12 positive. Gleason 6. involving up to 75%
da Vinci at Wash U, Barnes on 11/02/09
Modified Pathology, Gleason 4 + 3 = 7. Gleason 7 present throughout Prostate.  Negative surgical margins
4 of 4 periprostatic Lymph Nodes Negative, 10 of 10 pelvic Lymph Nodes Negative. Seminal Vesicles tumor free. No prostate extension
Post-op PSA 12/10/2009, Undetectable
12/12/2009, Pad Free and Started jogging.


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 3/13/2010 9:49 AM (GMT -6)   
Nice and simple, I like that
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12  same time, 2/8-Cath #11 out - 21 days, 3/2- Cath #12 out - 41 days, 3/2- Corr Surgery #5, Caths #13 & #14 same time, 3/6 Cath #13 out - 4 days


Sephie
Veteran Member


Date Joined Jun 2008
Total Posts : 1804
   Posted 3/13/2010 9:53 AM (GMT -6)   
Hero, NED is generally used in cancer terminology to mean no evidence of disease (your DFS). Don't know that we'd need your third acronym - PSM - since the other 2 seem to cover positive margins (whether focal or multifocal). Also curious as to what "extensive positive margin" means - would that refer to the size of the margin or the # of areas where cancer tissue was found? Just curious.
Husband diagnosed in 2/2008 at age 57 with stage T1c. Robotic surgery performed 3/2008. Stage upgraded to T3a (solitary focus of extraprostatic extension). Perineural tumor infiltration present. Apex margin, bladder neck and SVs negative. Final Gleason 3+4. PSA: 0.0 til July 2009. August 2009- 0.1, September 0.3, October back to 0.0, December 0.0. Thank you God!


Herophilus
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Date Joined Sep 2009
Total Posts : 664
   Posted 3/13/2010 10:47 AM (GMT -6)   

Sephie,

These are not my abbreviations (i'm not that clever). They come from the evidence based multi-center studies that I have been pouring over since my brother had his pathology shock last week. So anybody that is currently reading newly published oncology material relating to prostate cancer and positive surgical margins is going to come across these abbreviations frequently. In answer to your question a FPM is less than/equal to 3 mm. EPM was defined as greater than 3 mm.

Hero

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