Info. on Positive surgical margins

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

dkob131
Regular Member


Date Joined Apr 2008
Total Posts : 364
   Posted 3/20/2010 8:47 AM (GMT -6)   
 
David
 54 y.o.
 Diagnosed 4/10/08
 DRE Normal
 PSA-5.5
 Biopsy- 12 cores, 4 positive highest 4+4=8
 Bone scan, CT scan and Chest X-ray clear 4/16/08
 Urologist suggested surgery 4/16/08
 MRI on 4/24/08 clear no suggestion of lymph node   involvement.
 4/24/08 -Started on Lupron and Casodex preparing for HDRT and IMRT in late July.  This treatment will not preclude me from surgery if I change my mind.
Decide to have DaVinci surgery after another consult with surgeon.
6/19/08- DaVinci surgery at University of Washington.
6/25/08- Path report, clear margins, no noted extension
9/12/08- PSA <0.02 
12/05/08-PSA <0.02 Six months after surgery 
3/02/09-PSA <0.02 Nine months after surgery
5/02/09-PSA .10
8/17/09-PSA .21 Begin HT and set up for SRT to begin in 2 months.
 


60Michael
Veteran Member


Date Joined Jan 2009
Total Posts : 2243
   Posted 3/20/2010 9:29 AM (GMT -6)   
Thanks david. I read and then re-read it. Now I will wait for one of our Doc's on board to help make sense of it for me. Never have liked the word "mortality"
Michael
Dx with PCA 12/08 2 out of 12 cores positive 4.5 psa
59 yo when diagnosed, 61 yo 2010
Robotic surgery 5/09 Atlanta, Ga
Catheter out after 10 days
Gleason upgraded to 3+5, volume less than 10%
2 pads per day, 1 depends but getting better,
 started ED tx 7/17, slow go
Post op dx of neuropathy
T2C left lateral and left posterior margins involved
3 months psa.01, 6 month psa.4, 6 1/2 month psa.5
Starting IMRT on 1/18/10, Completed 39 tx at 72 gys on 3/12/10
Great family and friends
Michael


medved
Veteran Member


Date Joined Nov 2009
Total Posts : 1100
   Posted 3/20/2010 9:50 AM (GMT -6)   
I read this to say PSM makes patient more likely to have local or biochemical recurrence (and thus to need further treatment), but not demonstrably more likely to result in systemic disease or death.  The last finding is interesting/encouraging.
 
I would like to have seen results compared among  adjuvant RT, adjuvant ADT, salvage RT and salvage ADT, and the various combinations of those.
 
 
Age 45.  Father died of p ca. 
My psa starting age 40: 1.4, 1.3, 1.43, 1.74, 1.7, 1.5
 


60Michael
Veteran Member


Date Joined Jan 2009
Total Posts : 2243
   Posted 3/20/2010 11:26 AM (GMT -6)   
Thanks Medved, I like your read on it.
Michael
Dx with PCA 12/08 2 out of 12 cores positive 4.5 psa
59 yo when diagnosed, 61 yo 2010
Robotic surgery 5/09 Atlanta, Ga
Catheter out after 10 days
Gleason upgraded to 3+5, volume less than 10%
2 pads per day, 1 depends but getting better,
 started ED tx 7/17, slow go
Post op dx of neuropathy
T2C left lateral and left posterior margins involved
3 months psa.01, 6 month psa.4, 6 1/2 month psa.5
Starting IMRT on 1/18/10, Completed 39 tx at 72 gys on 3/12/10
Great family and friends
Michael


Ricky2
Regular Member


Date Joined Dec 2009
Total Posts : 97
   Posted 3/20/2010 12:24 PM (GMT -6)   
This is definitely positive news for those of us that have PSM. My Uro was optimistic, I continue to be optimistic about my outcome.

"Get busy living, or get busy dying"

Ricky2
Age 70

PSA 5/2008- 3.6, PSA 7/2009- 6.1, retested 9/2009-5.1.
Biopsy 9/2009. 4 of 12 positive. Gleason 3+4=7
CT and bone scan negative.
Robotic De Vince Surgery 10/29/2009. 1 night in hospital. No pain. Cath out on 11/6
Pathology Report: Gleason score 3+4. Margins slightly involved <.1mm to .25mm. Perineural invasion present, stage pT2c. Tumor 18%. Seminal Vesicle - absent, Lymph Nodes 0 of 6.
Continence- first 4 weeks after cath out Dry at night, rest of time, bladder held nothing. 6-7 pads per day. as of 12/30 no pads most of time. almost dry except for a few drips. I keep doing Kegels.
ED. Started VED on 12/17/2009. Every other day for 15 min. Cialis .20 mm twice a week
PSA 02/08/2010 <.1
02/22/10 Trimex injection .2ml less than 50% just a little discomfort.

New Topic Post Reply Printable Version
Forum Information
Currently it is Tuesday, September 18, 2018 6:46 PM (GMT -6)
There are a total of 3,004,443 posts in 329,145 threads.
View Active Threads


Who's Online
This forum has 161739 registered members. Please welcome our newest member, pinky;spoorback.
256 Guest(s), 7 Registered Member(s) are currently online.  Details
sebreg, jberda1, Serfr, annie42, InTheShop, Aurora2013, straydog