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New Member

Date Joined Mar 2010
Total Posts : 2
   Posted 3/28/2010 3:09 PM (GMT -6)   
Greetings folks,

I've not yet been diagnosed, but will be hearing back from my urologist next week with a report and I'm preparing myself for the worst. Situation: Age 50, baseline PSA screening done in March 2009, Total 2.9 Free PSA 9%. No doctor ever talked to me about those numbers and I didn't think to ask. Repeat test in March 2010: Total PSA 4.3, Free PSA 5%. Over the years I've had a gradual increase of urinary symptoms such as frequency and urgency that I describe as minor but noticeable. I have a small bladder diverticulum (probably congenital) that was d/x in 2009 following a minor UTI that cleared up with a 7 day course of Cipro. I haven't had any problems since.

Following the latest PSA test, my primary care doc recommended I visit a urologist. The local doctor I saw examined me (DRE negative) and recommended the standard 3 week trial of Cipro. However, at the same time I made arrangements to go to UCLA Medical Center to be seen by the very excellent Dr. Leonard A. Marks.

At UCLA Dr. Marks explained that my PSA numbers were troubling and in his experience, he finds the antibiotics are unreliable and told me he would be remiss to send me home without a biopsy. Hence, I was examined, given a repeat PSA test, a PCA3 test, a pelvic MRI using a 3T scanner with contrast and a ultrasound guided 12 core biopsy all in the same week. BTW, my biopsy used image processing software that takes the MR images and overlays them with the live ultrasound to create a 3D reconstruction of the gland in real time. The doctor can then target specific areas of interest to obtain the cores. This was fascinating to watch on the monitor and the biopsy itself was a piece of cake for me. I've had far worse experiences at the dentist!

The good news was there were no "areas of interest" as far as the imaging was concerned. In other words, both the MRI and ultrasounds were negative for any visible abnormalities. Instead the core locations were based more or less on a normal pattern, only in my case, mapped to the specific anatomical shape of my gland. The prostate volume I think was on the small side (30cc I recall hearing him say).

So, I should have a report after the slides are reviewed by the pathology lab and we can decide what to do from there. No matter what they say, I'm not worried, or scared. It's life. It is what it is and whatever happens I can deal with it, especially after finding this great community of knowledgeable PCa warriors.

Heal well!

// Gary

P.S. Still getting some rectal bleeding 2 days after biopsy. Otherwise feel great. Is this normal?

Veteran Member

Date Joined Jan 2009
Total Posts : 2243
   Posted 3/28/2010 3:19 PM (GMT -6)   
Welcome Gary and it sounds like you have been studying prostate "stuff." Good for you but let's hope you get a green light with no problems. Your PSA sounds a little like mine prior to the biopsy however, not sure I would read too much into that at this point given your other health problems which required Cipro. Keep us posted and once again welcome.
Dx with PCA 12/08 2 out of 12 cores positive 4.5 psa
59 yo when diagnosed, 61 yo 2010
Robotic surgery 5/09 Atlanta, Ga
Catheter out after 10 days
Gleason upgraded to 3+5, volume less than 10%
2 pads per day, 1 depends but getting better,
 started ED tx 7/17, slow go
Post op dx of neuropathy
T2C left lateral and left posterior margins involved
3 months psa.01, 6 month psa.4, 6 1/2 month psa.5
Starting IMRT on 1/18/10, Completed 39 tx at 72 gys on 3/12/10
Great family and friends

Elite Member

Date Joined Oct 2008
Total Posts : 25393
   Posted 3/28/2010 3:51 PM (GMT -6)   
Gary, Hello and welcome to HW Prostate Cancer. Glad you found us, and it sounds like you are already in the hands of a good urologist, which is important at this stage.

BTW, the rectal bleeding is not uncommon at this point. Bleeding there, as well as in your urine at first, and in your ejaculate, pretty typical. How long and how much, varies from guy to guy, and also how extensive your biopsy was, I think you said you had a 12 core.

No seeing any areas of "interest" is not conclusive by itself. With a minute speck of PCa, it may not be enough to show up as my dr. called it, "a suspicious shadow". When you get the results of the pathology of this biopsy, please come back and tell us what is going on.

At 30cc, your prostate is a little on the small size, but hey ,who's comparing.

I hope you come up clean, but if you have cancer, this is great place to belong to. A lot of knowledge, a lot of compassion and caring, and the brothers and sisters here, support each other very well.

Good luck,

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12  same time, 2/8-Cath #11 out - 21 days, 3/2- Cath #12 out - 41 days, 3/2- Corr Surgery #5, Caths #13 & #14 same time, 3/6 Cath #13 out - 4 days

Veteran Member

Date Joined Apr 2009
Total Posts : 990
   Posted 3/28/2010 6:38 PM (GMT -6)   
Let us give you a short term welcome with the hope that you will have no reason to be here longer.

It sounds like you are in very good hands in terms of your medical care. Your stats are at the bottom end of where worry starts so it is likely that, even if PC is diagnosed you will have lots of options and lots of time to decide.

The really scary aftereffect of a biopsy is blood in the semen. It can happen for up to two weeks after -- not a sign of trouble, just normal for the procedure.
Age at diagnosis 66, PSA 5.5
Biopsy 12/08 12 cores, 8 positive
Gleason 3+4=7
CAT scan, Bone scan 1/09 both negative.

Robotic surgery 03/03/09 Catheter Out 03/08/09
Pathology: Lymph nodes & Seminal vesicles negative
Margins positive, Capsular penetration extensive Gleason 4+3=7
6 weeks: 1 pad/day, 1 pad/night -- mostly dry at night.
10 weeks: no pad at night -- slight leakage day/1 pad.
3 mo. PSA 0.0 - now light pads
6 mo. PSA 0.00 -- 1 light pad/day
9 mo. PSA 0.00 -- 1 light pad/day ED remains

John T
Veteran Member

Date Joined Nov 2008
Total Posts : 4269
   Posted 3/28/2010 6:58 PM (GMT -6)   
A 3T mri with contrast should have picked up anything significant. You did much more than any 1st time patient and that is a credit to you. If you do have a small cancer it should be easily taken care of.

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.


English Alf
Veteran Member

Date Joined Oct 2009
Total Posts : 2218
   Posted 3/29/2010 3:57 AM (GMT -6)   
Welcome Gary

Your report of how they tested you at UCLA sounds excellent.

Rectal bleeding should clear up quickly,
blood in urine or the odd blood clot may show up for a few days.
blood in semen mayl continue for at least a month (will be dark brown)

Hope you get good news


James C.
Veteran Member

Date Joined Aug 2007
Total Posts : 4463
   Posted 3/29/2010 1:08 PM (GMT -6)   
Welcome Gary95, to HW.
James C. Age 63
Gonna Make Myself A Better Man
4/07: PSA 7.6, Recheck after 4 weeks Cipro-6.7
7/07 Biopsy: 3 of 16 PCa, 5% invloved, left lobe, GS3+3=6
9/07: Nerve Sparing open RRP, 110gms, Path Report- Stg. pT2c, 10 gms., margins clear
32 Months: PSA's .04 each test since surgery, ED continues: Bimix- .3ml PRN, Trimix- .15ml PRN

New Member

Date Joined Mar 2010
Total Posts : 2
   Posted 3/30/2010 6:29 PM (GMT -6)   
Thank you everybody! You guys are quite an inspiration and have built up an excellent community full of knowledge, information, and support. It has been through here that I began the process of educating myself about PCa. I will certainly share the results of my tests with you. One result came back today - my repeat PSA test from UCLA is unexpectedly lower at 2.1 ng/mL, and Free at 11%. PCA3 and biopsy results to follow...

Keep up the good fight!

// Gary

New Member

Date Joined Nov 2008
Total Posts : 15
   Posted 4/1/2010 3:57 PM (GMT -6)   


My stats are fairly similar to yours, PSA up and down, % free PSA on the low side.  At my last uro appt last December, doc attributed elevated PSA to minor inflammation.  Even with courses of ibuprofin and antibiotics, PSA would rise then fall later.  2 biopsies found nothing.  Uro said to see him again in a year with repeat PSA test.  I'll have my GP retest it 6 months from last test just for some peace of mind.  I really freaked when my PSA/%free PSA tests started to look bad, convinced myself I had cancer.  

In Walsh's book he states that PSA swings are usually indicative of a benign condition, hopefully that's the case for us.


Age 49
PSA 6/2003 1.5
PSA 7/2/2008 4.8, % free PSA 8
PSA 7/14/2008 5.2, % free PSA 8
3 weeks Levaquin
PSA 9/2008 5.8, % free PSA 7
Biopsy 10/08 10-core all neg, no sign of PCa, told prostate was enlarged
PSA 12/2008 5.2, % free PSA 7
PSA 2/2009 4.7, % free PSA 8
PSA 5/2009 5.2, % free PSA 8
Biopsy 6/2009 12-core all neg, no sign of PCa, prostate "slightly enlarged".
PSA 11/2009 4.6, % free PSA 11

Veteran Member

Date Joined Aug 2007
Total Posts : 1015
   Posted 4/1/2010 8:12 PM (GMT -6)   
Hi Gary95,
'Good to see a "brother from another mother" taking care of his health.
Like others, I hope your stay here is only temporary.
All the best to you,
Surgery: Da Vinci; July 31, 2007; 54 on surgery day;
Pathology: PSA: 4.3; Gleason: 3+3=6; T2a; Confined to Prostate;
Post RP PSAs: 09/'07 <0.04; 12/'07 <0.04; 03/'08 <0.04;
06/'08 <0.04; 12/'08 <0.04; 06/'09 =0.06; 09/'09 <0.04; 12/'09 =0.05;
Latest PSA 3/'10 <0.04

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