Has anyone had experience with the seed implant radiation? Was No Subject

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

ridgewalker
New Member


Date Joined Mar 2010
Total Posts : 7
   Posted 4/13/2010 10:31 AM (GMT -6)   
Has anyone had experience with the seed implant radiation?
are side effects such as incontinence common?

65 yrs
3+4=7 Gleason score
6.1 psa
bone and cat scans neg.
diagnosed 3/18/10

Added a Subject for archiving and searching.

Post Edited By Moderator (James C.) : 4/13/2010 10:41:55 AM (GMT-6)


Wigs
Regular Member


Date Joined Mar 2009
Total Posts : 89
   Posted 4/13/2010 10:39 AM (GMT -6)   
Ridgewalker,

While it was over 10 years ago that I had brachytherapy and was 46 at the time, I didn't experience incontinence.

Wigs
Diagnosed @ age 47 - September 1997
PSA 5 / Gleason 3+3
Seed Implant - January 1998 @ Trident Hospital, SC
PSA 2.4 - July 2007
PSA 2.7 - July 2008
PSA 3.0 - November 2008
Diagnosed @ age 57 - December 2007
Gleason 4+3
Salvage Prostatectomy & Colostomy - March 2008 @ MSKCC, NY
Suprapubic cathether installed - July 2008 @ Cleveland Clinic, OH
Urethral-Rectal Fistula Repair - August 2008 @   Cleveland Clinic, OH
PSA < .03 - Aug 2008
Penile catheter removed October 2008
Suprapubic catheter removed December 2008
Colostomy Reversal - January 2009 @ Cleveland Clinic
Urethral stricture removed - January 2009 @ Cleveland Clinic
(Total incontinence - 4 diapers & 6 - 8 pads per 24 hour period)
PSA < .03 - Jan 2009
AUS implant - May 2009 @ Cleveland Clinic
PSA < .03 - May 2009
AUS activated - July 2009
(Wearing a light pad daily.)
PSA < .03 - July 2009
Penile Implant - December 2009 @ Cleveland Clinic
PSA < .03 - December 2009
Penile Implant activated - February 2010
 
 


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 4/13/2010 10:46 AM (GMT -6)   
Ridge, perhaps JohnT and Tudpock can chime in when they see this, they both have good ongoing experiences with "seeding", and there are a couple of others here too.

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery, no problem post SRT
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 43 days, 1/19 - Corr Surgery #4,  Caths #11 and #12  same time, 2/8-Cath #11 out - 21 days, 3/2- Cath #12 out - 41 days, 3/2- Corr Surgery #5, 3/6 Cath #13 out - 4 days, Cath #14 out - 27 days, Cath #15 - 3/29


JoeFL
Regular Member


Date Joined Oct 2009
Total Posts : 420
   Posted 4/13/2010 10:55 AM (GMT -6)   
Ridgewalker,
 
Had seeds implanted on 12/11/09 followed by 25 IGRT sessions (see below). I experienced no incontinence from either one. There are some other side effects but they seem to be clearing up.
 
Joe

Age -67 PSA - 4.5

Biopsy  (9/4/09) - Positive in 5 of 8 cores. In those 5 cores, 5 of 11 samples were positive. Gleason 3+3=6. Stage – T1C  Ct and Bone scans negative.

 

BT performed on 12/11/09. 84 seeds of Palladium 103. Surgery at 7:30 - Home at 12:30 same day with no catheter. Blood in urine for a week. Side effects as expected -  some burning, frequency, urgency.   Resumed daily  1 ½ mile walk after 3 days. 

 

BT followed with 25 IGRT treatments beginning Feb 15 (4500 Gy's). After third week, experienced some fatigue. Now 3 weeks from last treatment - energy level returning. Burning and urgency is improved.

 


Tudpock18
Forum Moderator


Date Joined Sep 2008
Total Posts : 4157
   Posted 4/13/2010 11:34 AM (GMT -6)   

Ridge, specific to your question:

1.  Yes, I have had the seeds and you can read my experience in detail by selecting the link in my signature.

2.  Incontinence is not a usual side effect of bracytherapy.  The most common urinary side effects are urgency and frequency for the first 2-3 months post implantation.  Those SE's are easily controlled with Flomax and adopting a short term diet that limits caffeine, alcohol and spicy foods.

I am personally a big booster of this procedure because, depending on the patient, it delivers cure rates equal to surgery but with significantly less onerous side effects.

Tudpock


Age 62, Gleason 4 +3 = 7, T1C, PSA 4.2, 2 of 16 cores cancerous, 27cc
Brachytherapy December 9, 2008.  73 Iodine-125 seeds.  Procedure went great, catheter out before I went home, only minor discomfort.  Regular activities resumed, everything continues to function normally as of 12/09.  6 month PSA 1.4 and now 1 year PSA at 1.0.  My docs are "delighted"!

John T
Veteran Member


Date Joined Nov 2008
Total Posts : 4229
   Posted 4/13/2010 3:34 PM (GMT -6)   
Incontinence is rare with Brachytherapy. Usual side affects are what Tud has stated. There is about a 5% occurance of rectal bleeding down the road, but most of the time it goes away. Some patients need argone lazer surgery to correct the bleeding.
It is key to get an experienced Brachytherapist who has done at least 500 procedures. As with any treatment the doctor's skill is the most important factor in limiting any side affects.
Other than 4 weeks of urinary frequency and urgency I have had no side affects at all.
JT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT

New Topic Post Reply Printable Version
Forum Information
Currently it is Saturday, June 23, 2018 7:25 PM (GMT -6)
There are a total of 2,974,630 posts in 326,194 threads.
View Active Threads


Who's Online
This forum has 161293 registered members. Please welcome our newest member, Lymegone.
363 Guest(s), 10 Registered Member(s) are currently online.  Details
tarawa, bluelyme, acarined, hennaheather, mattamx, Gear, John T, Sara14, statback, Saipan Paradise